Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies

Autor: Eli Hatchwell, Edward B. Smith, Shapour Jalilzadeh, Christopher D. Bruno, Yassine Taoufik, Houria Hendel-Chavez, Roland Liblau, David Brassat, Guillaume Martin-Blondel, Heinz Wiendl, Nicholas Schwab, Irene Cortese, Maria Chiara Monaco, Luisa Imberti, Ruggero Capra, Jorge R. Oksenberg, Jacques Gasnault, Bruno Stankoff, Todd A. Richmond, David M. Rancour, Igor J. Koralnik, Barbara A. Hanson, Eugene O. Major, Christina R. Chow, Peggy S. Eis

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

BackgroundProgressive multifocal leukoencephalopathy (PML) is a rare and often lethal brain disorder caused by the common, typically benign polyomavirus 2, also known as JC virus (JCV). In a small percentage of immunosuppressed individuals, JCV is re

Externí odkaz: https://doaj.org/article/1490902a359c49238be460026325caaf

Follicular CD4 T Cells Tutor CD8 Early Memory Precursors: An Initiatory Journey to the Frontier of B Cell Territory

Autor: Marie-Ghislaine de Goër de Herve, Maïsa Abdoh, Salma Jaafoura, Deniz Durali, Yassine Taoufik

Publikováno v: iScience, Vol 20, Iss , Pp 100-109 (2019)

Summary: The early events of CD8 memory generation remain largely unknown. Here we report that as early as 2 days after antigen priming, very early memory precursors can be identified by their expression of the chemokine receptor CXCR5. These early p

Externí odkaz: https://doaj.org/article/f8097d9a864140a9b86920bdaa647a43

Increased Production of B-Cell Activating Cytokines and Altered Peripheral B-Cell Subset Distribution during HIV-Related Classical Hodgkin Lymphoma

Autor: Raphael, Lievin, Houria, Hendel-Chavez, Aliou, Baldé, Rémi, Lancar, Michèle, Algarte-Génin, Roman, Krzysiek, Dominique, Costagliola, Lambert, Assoumou, Yassine, Taoufik, Caroline, Besson

Publikováno v: Cancers, Vol 14, Iss 128, p 128 (2022)
Cancers
Cancers, 2022, 14 (1), pp.128. ⟨10.3390/cancers14010128⟩

Simple Summary Patients with HIV are at high risk of developing Hodgkin’s lymphoma. This is potentially due to alterations in blood circulating B-lymphocytes and their activating cytokines. We analyzed the distribution of circulating B-lymphocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9cfcafe87e73370087e4adcec42207f7
https://www.mdpi.com/2072-6694/14/1/128

Prolonged in‐hospital stay and higher mortality after Covid‐19 among patients with non‐Hodgkin lymphoma treated with B‐cell depleting immunotherapy

Autor: Roberta Di Blasi, Laure Philippe, Thomas Hueso, Catherine Thieblemont, Karine Lacombe, Bénédicte Deau Fischer, Serge Bologna, Caroline Besson, Guillemette Fouquet, Sylvain Choquet, Milena Kohn, Rémy Duléry, Carole Soussain, Bernard Drenou, Pierre Feugier, Etienne Daguindau, Marc Delord, Nicolas Noel, Adrien Chauchet, Sylvain Lamure, Sandra Malak, Cédric Rossi, Bertrand Joly, Guillaume Cartron, Yassine Taoufik

Publikováno v: American Journal of Hematology
American Journal of Hematology, Wiley, 2021, 96 (8), pp.934-944. ⟨10.1002/ajh.26209⟩
American Journal of Hematology, 2021, 96 (8), pp.934-944. ⟨10.1002/ajh.26209⟩

International audience; Prolonged Covid-19 is an emerging issue for patients with lymphoma or immune deficiency. We aimed to examine prolonged length of in-hospital stay (LOS) due to Covid-19 among patients with lymphoma and assess its determinants a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c93552a83f08f61d53fc23e10bf133
https://doi.org/10.1002/ajh.26209

Frequent altered distribution of peripheral B-lymphocyte subsets in pediatric and adolescent patients with classical Hodgkin lymphoma

Autor: Leila Hamdi, Roman Krzysiek, Thierry Leblanc, Rita Creidy, Houria Hendel-Chavez, Patricia Hugues, S. Boudjemaa, Caroline Besson, Judith Landman-Parker, Aurore Coulomb, Yassine Taoufik

Publikováno v: Leukemia & Lymphoma. 62:300-307

Peripheral lymphopenia is a well-known negative prognostic marker in classical Hodgkin lymphoma (cHL). We characterized the peripheral B-cell compartment in a prospective cohort of 83 pediatric cHL patients. We observed significantly low total B-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5093bc588afae1b5402f308b68cb2f2
https://doi.org/10.1080/10428194.2020.1834090