Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yasser S. Abdel-Ghany"'
Autor:
Yasser S. Abdel-Ghany, Sherine N. Khattab, Omnia M. Ali, Ahmed O. Elzoghby, Mohamed Teleb, Maged W. Helmy, Adnan A. Bekhit
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 188:110824
Despite the clinical approval of few nanomedicines for cancer therapy, some drawbacks still impede their improved efficiency including low drug loading, off-target toxicity and development of multi-drug resistance. Herein, lactoferrin (Lf)-coupled me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0ae85a901aadaa7efa95774623d2f1
https://doi.org/10.1016/j.colsurfb.2020.110824
https://doi.org/10.1016/j.colsurfb.2020.110824
Autor:
Dharmarajan Sriram, Yasser S. Abdel-Ghany, Perihan A. Elzahhar, Soad A.M. El-Hawash, Rasha A. Nassra, Manal N. S. Saudi, Nayera W. Hassan, Marwa M. Abdel-Aziz, Azza Ismail
Publikováno v:
Bioorganic Chemistry. 96:103610
TB continues to be a leading health threat despite the availability of powerful anti-TB drugs. We report herein the design and synthesis of various hybrid molecules comprising pyrazine scaffold and various formerly identified anti-mycobacterial moiet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd163f760335440fa3a05822b950ac0
https://doi.org/10.1016/j.bioorg.2020.103610
https://doi.org/10.1016/j.bioorg.2020.103610
Autor:
Ahmed S.F. Belal, Rasha A. Nassra, Yasser S. Abdel-Ghany, Rana Alaaeddine, Lynn M. Alaeddine, Ahmed F. El-Yazbi, Ghandoura Moussa, Aly A. Hazzaa, Azza Ismail
Publikováno v:
European journal of medicinal chemistry. 144
Click chemistry was used to synthesize a new series of thioquinazolinone molecules equipped with propargyl moiety,1,2,3-triazolyl and isoxazolyl rings. Our design was based on merging pharmacophores previously reported to exhibit COX-2 inhibitory act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a9eda19bc540bb0042d8816e7a3ef7
https://pubmed.ncbi.nlm.nih.gov/29289887
https://pubmed.ncbi.nlm.nih.gov/29289887
Autor:
Yasser S. Abdel-Ghany, Alaa A. El-Tombary, Farid S. G. Soliman, S. A. Shams El-Dine, Ahmad S. F. Belal
Publikováno v:
Medicinal Chemistry Research. 20:865-876
In search for novel anti-cancer and anti-microbial agents with promising pharmacotoxicological profile, the synthesis of some substituted 4-halofuran-2(5H)-ones (8a–l, 9, 11) and derived halogenated quinoxalin-2(1H)-ones (12a–d) is described. Som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8502e68e6845476148c7b7bc58a06dff
https://doi.org/10.1007/s00044-010-9394-2
https://doi.org/10.1007/s00044-010-9394-2
Publikováno v:
Letters in Organic Chemistry. 5:316-318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d17a2e0610df427031d4883ed8bf7f
https://doi.org/10.2174/157017808784049416
https://doi.org/10.2174/157017808784049416
Autor:
Isaac O. Donkor, Yasser S. Abdel-Ghany, Duane D. Miller, Peter F. Kador, Anita Bartoszko-Malik, Tadashi Mizoguchi
Publikováno v:
European Journal of Medicinal Chemistry. 33:15-22
We have synthesized alrestatin derivatives 1–11 possessing acyl benzenesulfonamide groups as surrogates for the carboxylic acid moiety of alrestatin. Most of the compounds were inactive as aldose reductase inhibitors compared to alrestatin, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec414fb0bcf542be8f8195c952e4bf3
https://doi.org/10.1016/s0223-5234(99)80071-3
https://doi.org/10.1016/s0223-5234(99)80071-3
Autor:
Peter F. Kador, Yasser S. Abdel-Ghany, Duane D. Miller, Isaac O. Donkor, Anita Bartoszko-Malik, Tadashi Mizoguchi
Publikováno v:
ChemInform. 29
We have synthesized alrestatin derivatives 1–11 possessing acyl benzenesulfonamide groups as surrogates for the carboxylic acid moiety of alrestatin. Most of the compounds were inactive as aldose reductase inhibitors compared to alrestatin, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c6cb55889d4b1e133cde707fd776737
https://doi.org/10.1002/chin.199828119
https://doi.org/10.1002/chin.199828119
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac5f80892e454305edb778b6575cc58
https://doi.org/10.1002/chin.200840150
https://doi.org/10.1002/chin.200840150
Autor:
Hayam M. A. Ashour, Yasser S. Abdel Ghany, Adnan A. Bekhit, Azza M. Baraka, Alaa El‐Din A. Bekhit
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67f480c68b0d75a4049c01891e9d953c
https://doi.org/10.1002/chin.200830120
https://doi.org/10.1002/chin.200830120
Autor:
Yasser S. Abdel Ghany, Alaa El-Din A. Bekhit, Adnan A. Bekhit, Azza M. Baraka, Hayam M. A. Ashour
Publikováno v:
European journal of medicinal chemistry. 43(3)
Four series of pyrazolyl benzenesulfonamide derivatives have been synthesized. The first series was prepared by cyclization of the intermediate N,N-dimethylaminomethylene-4[3-phenyl-4-(substituted thiosemicarbamoyl hydrazonomethyl)-1H-pyrazol-1-yl]be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca78389d84f076f685add85c4a8db0a
https://pubmed.ncbi.nlm.nih.gov/17532544
https://pubmed.ncbi.nlm.nih.gov/17532544