Výsledky vyhledávání - "Yasmine Zerdoumi"

Akademický článek

Role of the LytSR Two-Component Regulatory System in Staphylococcus lugdunensis Biofilm Formation and Pathogenesis

Autor: Sandrine Dahyot, Virginie Oxaran, Maïté Niepceron, Eddy Dupart, Stéphanie Legris, Laurie Destruel, Jennifer Didi, Thomas Clamens, Olivier Lesouhaitier, Yasmine Zerdoumi, Jean-Michel Flaman, Martine Pestel-Caron

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Staphylococcus lugdunensis is a coagulase negative Staphylococcus recognized as a virulent pathogen. It is responsible for a wide variety of infections, some of which are associated with biofilm production, such as implanted medical device infections

Externí odkaz: https://doaj.org/article/9ebca7eb9af340beaa80a2b894305902

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Akademický článek

Proteomic and transcriptomic study of brain microvessels in neonatal and adult mice.

Autor: Baptiste Porte, Clémence Chatelain, Julie Hardouin, Céline Derambure, Yasmine Zerdoumi, Michèle Hauchecorne, Nicolas Dupré, Soumeya Bekri, Bruno Gonzalez, Stéphane Marret, Pascal Cosette, Philippe Leroux

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0171048 (2017)

Infants born before 29 weeks gestation incur a major risk of preterm encephalopathy and subependymal/intracerebral/intraventricular haemorrhage. In mice, an ontogenic window of haemorrhage risk was recorded up to 5 days after birth in serpine1 knock-

Externí odkaz: https://doaj.org/article/3a6f268746c4485996ae40b3d7770170

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Role of the LytSR Two-Component Regulatory System in Staphylococcus lugdunensis Biofilm Formation and Pathogenesis

Autor: Yasmine Zerdoumi, Laurie Destruel, Maïté Niepceron, Thomas Clamens, Jean-Michel Flaman, Olivier Lesouhaitier, Virginie Oxaran, Stéphanie Legris, Jennifer Didi, Eddy Dupart, Sandrine Dahyot, Martine Pestel-Caron

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25de6389a9442bae06586b3d578de7
https://doi.org/10.3389/fmicb.2020.00039

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A new genotoxicity assay based on p53 target gene induction

Autor: Jean-Michel Flaman, Gaëlle Bougeard, Soubigou F, Edwige Kasper, Thierry Frebourg, Yasmine Zerdoumi, Sahil Adriouch

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2015, 789-790, pp.28-35. ⟨10.1016/j.mrgentox.2015.05.010⟩

The p53 tumor suppressor protein has emerged as a universal sensor of genotoxic stress that regulates the transcription of numerous genes required for appropriate cellular response to DNA damage. Therefore, transcriptional induction of p53 target gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826f5991a926c38855e01a66ac7de759
https://doi.org/10.1016/j.mrgentox.2015.05.010

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PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks

Autor: Dominique Duterte-Boucher, Jean-Michel Flaman, Hélène Lacaille, Hubert Vaudry, Hitoshi Hashimoto, David Vaudry, Yasmine Zerdoumi

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2017, 54 (9), pp.7534-7548. ⟨10.1007/s12035-016-0204-9⟩
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Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid neuropeptide which has been shown to exert various neuroprotective actions in vitro and in vivo; however, the ability of endogenous PACAP to prevent cell death in vivo rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a222e8a02bb1f62094339549bb31420c
https://hal-normandie-univ.archives-ouvertes.fr/hal-01928339

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Major remodeling of brain microvessels during neonatal period in the mouse: A proteomic and transcriptomic study

Autor: Antoine Obry, Baptiste Porte, Thierry Lequerré, Soumeya Bekri, Yasmine Zerdoumi, Bruno J. Gonzalez, Céline Derambure, Philippe Leroux, Julie Hardouin, Pascal Cosette, Nicolas Dupré, Jean-Michel Flaman, Michèle Hauchecorne, Stéphane Marret

Publikováno v: Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2016, 37 (2), pp.495-513. ⟨10.1177/0271678X16630557⟩

Preterm infants born before 29 gestation weeks incur major risk of subependymal/intracerebral/intraventricular hemorrhage. In mice, neonate brain endothelial cells are more prone than adult cells to secrete proteases under glutamate challenge, and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199839f997a80727229436c7e537df87
https://hal-normandie-univ.archives-ouvertes.fr/hal-02445344

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Changements métaboliques dans la microcirculation cérébrale du nouveau-né à l’adulte : une étude protéomique et transcriptomique

Autor: Philippe Leroux, Pascal Cosette, Nicolas Dupré, Yasmine Zerdoumi, Bruno Jose Gonzales, Baptiste Porte, Soumeya Bekri, Julie Hardouin, Michèle Hauchecorne, Stéphane Marret, Céline Derambure

Publikováno v: Morphologie. 101:247

But Les lesions cerebrales perinatales entrainent des handicaps durables entrainant une prise en charge couteuse et longue des patients. Le type de lesion va dependre du stade de developpement du cerveau. Ainsi, des hemorragies sub-ependymaire/intrac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2236cea9a512f88825bd0aed1517a7db
https://doi.org/10.1016/j.morpho.2017.07.021

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Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage

Autor: Yasmine Zerdoumi, Raphaël Lanos, Sabine Raad, Jean-Michel Flaman, Gaëlle Bougeard, Thierry Frebourg, Isabelle Tournier

Publikováno v: Human Molecular Genetics
Publons
Human Molecular Genetics, Oxford University Press (OUP), 2017, 26 (14), pp.2591-2602. ⟨10.1093/hmg/ddx165⟩

Li-Fraumeni Syndrome (LFS) results from heterozygous germline mutations of TP53, encoding a key transcriptional factor activated in response to DNA damage. We have recently shown, from a large LFS series, that dominant-negative missense mutations are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b043f2a7ebb691dcc11f07d6720798c
http://europepmc.org/articles/PMC5886279

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Drastic Effect of Germline TP53 Missense Mutations in Li-Fraumeni Patients

Autor: Richard Sesboüé, Thierry Frebourg, Juliette Aury-Landas, Yasmine Zerdoumi, Mariette Renaux-Petel, Gaëlle Bougeard, Céline Derambure, Catherine Bonaïti-Pellié, Jean-Michel Flaman

Publikováno v: Human Mutation
Human Mutation, Wiley, 2013, 34 (3), pp.453-461. ⟨10.1002/humu.22254⟩

International audience; In contrast to other tumor suppressor genes, the majority of TP53 alterations are missense mutations. We have previously reported that in the Li–Fraumeni syndrome (LFS), germline TP53 missense mutations are associated with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecca92d74bf1d28e309de712f540f37
https://hal.archives-ouvertes.fr/hal-02329548

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