Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yasmine Driege"'
Autor:
Domien Vanneste, Jens Staal, Mira Haegman, Yasmine Driege, Marieke Carels, Elien Van Nuffel, Pieter De Bleser, Yvan Saeys, Rudi Beyaert, Inna S. Afonina
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 2008 (2022)
Prostate cancer (PCa) is one of the most common cancer types in men and represents an increasing global problem due to the modern Western lifestyle. The signalling adapter protein CARD14 is specifically expressed in epithelial cells, where it has bee
Externí odkaz:
https://doaj.org/article/f78b7b27b5104564903b8efdc49a5593
Autor:
Annelies Demeyer, Yasmine Driege, Ioannis Skordos, Julie Coudenys, Kelly Lemeire, Dirk Elewaut, Jens Staal, Rudi Beyaert
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101557- (2020)
Summary: The protease MALT1 is a key regulator of NF-κB signaling and a novel therapeutic target in autoimmunity and cancer. Initial enthusiasm supported by preclinical results with MALT1 inhibitors was tempered by studies showing that germline MALT
Externí odkaz:
https://doaj.org/article/337e806179514497a3fa9465289da0f0
Autor:
Annelies Demeyer, Elien Van Nuffel, Griet Baudelet, Yasmine Driege, Marja Kreike, David Muyllaert, Jens Staal, Rudi Beyaert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
MALT1 plays an important role in innate and adaptive immune signaling by acting as a scaffold protein that mediates NF-κB signaling. In addition, MALT1 is a cysteine protease that further fine tunes proinflammatory signaling by cleaving specific sub
Externí odkaz:
https://doaj.org/article/d20973f6d50e422aabc6d8f4e9ac7160
Autor:
Annelies Demeyer, Ioannis Skordos, Yasmine Driege, Marja Kreike, Tino Hochepied, Mathijs Baens, Jens Staal, Rudi Beyaert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-κB and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions. Because of its role in lymp
Externí odkaz:
https://doaj.org/article/d60c8053741f489185924cb3921ba44f
Autor:
Jens Staal, Yasmine Driege, Mira Haegman, Alice Borghi, Paco Hulpiau, Laurens Lievens, Ismail Sahin Gul, Srividhya Sundararaman, Amanda Gonçalves, Ineke Dhondt, Jorge H. Pinzón, Bart P. Braeckman, Ulrich Technau, Yvan Saeys, Frans van Roy, Rudi Beyaert
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The CARD–coiled coil (CC)/Bcl10/MALT1-like paracaspase (CBM) signaling complexes composed of a CARD–CC family member (CARD-9, -10, -11, or -14), Bcl10, and the type 1 paracaspase MALT1 (PCASP1) play a pivotal role in immunity, inflammation, and c
Externí odkaz:
https://doaj.org/article/901db44026754a8195006993055bd50c
Autor:
Laura Meloni, Lynn Verstrepen, Marja Kreike, Jens Staal, Yasmine Driege, Inna S. Afonina, Rudi Beyaert
Publikováno v:
Molecules, Vol 23, Iss 12, p 3144 (2018)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an intracellular cysteine protease (paracaspase) that plays an integral role in innate and adaptive immunity. The phenothiazine mepazine has been shown to inhibit the prote
Externí odkaz:
https://doaj.org/article/9d245db533fa4859b36b751093580da1
Autor:
Susan Broughton, Nazif Alic, Cathy Slack, Timothy Bass, Tomoatsu Ikeya, Giovanna Vinti, Anna Maria Tommasi, Yasmine Driege, Ernst Hafen, Linda Partridge
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3721 (2008)
The insulin/IGF-like signalling (IIS) pathway has diverse functions in all multicellular organisms, including determination of lifespan. The seven insulin-like peptides (DILPs) in Drosophila are expressed in a stage- and tissue-specific manner. Parti
Externí odkaz:
https://doaj.org/article/2895aaf0759d463a8f468891ef7cca47
Autor:
Janne M Toivonen, Glenda A Walker, Pedro Martinez-Diaz, Ivana Bjedov, Yasmine Driege, Howard T Jacobs, David Gems, Linda Partridge
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e95 (2007)
To investigate whether alterations in mitochondrial metabolism affect longevity in Drosophila melanogaster, we studied lifespan in various single gene mutants, using inbred and outbred genetic backgrounds. As positive controls we included the two mos
Externí odkaz:
https://doaj.org/article/841d7fe4ba734c9f8d7416dde90f89c4
CARD9, -10, -11 and -14 all belong to the CARD-coiled coil (CC) protein family and originated from a single common ancestral protein early in vertebrate evolution. All four proteins form CARD-CC/BCL10/MALT1 (CBM) complexes leading to NF-κB activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52927101b7ac689a58acb625bba84811
https://doi.org/10.1101/2023.03.06.531260
https://doi.org/10.1101/2023.03.06.531260
Autor:
Aurora Holgado, Zhuangzhuang Liu, Aigerim Aidarova, Christina Mueller, Mira Haegman, Yasmine Driege, Marja Kreike, Charlotte L. Scott, Inna S. Afonina, Rudi Beyaert
Publikováno v:
Journal of Allergy and Clinical Immunology.