Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yasmine, Amitay"'
Autor:
Shira Dorot, James Tankel, Victoria Doviner, Hilary Shmeeda, Yasmine Amitay, Patricia Ohana, Amir Dagan, Menachem Ben-Haim, Petachia Reissman, Alberto Gabizon
Publikováno v:
Cancer Chemotherapy and Pharmacology. 90:109-114
To examine the ex- vivo ability of explanted human tumors and normal tissue to activate liposomal mitomycin C lipidic prodrug (MLP) by releasing the active free drug form, mitomycin C (MMC).We tested conversion of MLP to MMC in an ex vivo assay using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4ea7163790b027a8692803266ced99
https://doi.org/10.1007/s00280-022-04451-1
https://doi.org/10.1007/s00280-022-04451-1
Autor:
Eli Sapir, Raphael Pfeffer, Marc Wygoda, Ofer Purim, Adi Levy, Benjamin Corn, Yasmine Amitay, Patricia Ohana, Alberto Gabizon
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5bfcd7a3d00ed67ab16669e9a45056e
https://doi.org/10.1016/j.ijrobp.2023.03.046
https://doi.org/10.1016/j.ijrobp.2023.03.046
Autor:
Hilary Shmeeda, Yasmine Amitay, Alberto Gabizon, Patricia Ohana, Talia Golan, Ravit Geva, Esther Tahover, Ruth Perets
Publikováno v:
Investigational New Drugs. 38:1411-1420
Background Pegylated liposomal (PL) mitomycin-c lipidic prodrug MLP) may be a useful agent in patients with metastatic colo-rectal carcinoma (CRC). We report here on the pharmacokinetics and clinical observations in a phase 1A/B study with PL-MLP. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55854abbb3aa55087e1cc60601321d35
https://doi.org/10.1007/s10637-020-00897-3
https://doi.org/10.1007/s10637-020-00897-3
Autor:
Patricia Ohana, Yasmine Amitay, Lidia Mak, Hilary Shmeeda, Jenny Gorin, Alberto A. Gabizon, Dina Tzemach
Publikováno v:
Cancer drug resistance (Alhambra, Calif.). 4(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900cafd5344973f035b57aea3c99982a
https://pubmed.ncbi.nlm.nih.gov/35582027
https://pubmed.ncbi.nlm.nih.gov/35582027
Autor:
Yogita Patil, Samuel Zalipsky, Yasmine Amitay, Gleb Kornev, Alberto Gabizon, Esther Tahover, Eli Sapir, Hilary Shmeeda, Patricia Ohana
Publikováno v:
Advanced drug delivery reviews.
Several liposome products have been approved for the treatment of cancer. In all of them, the active agents are encapsulated in the liposome water phase passively or by transmembrane ion gradients. An alternative approach in liposomal drug delivery c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ebe81149863eac6a342825571c6eac
https://pubmed.ncbi.nlm.nih.gov/32777239
https://pubmed.ncbi.nlm.nih.gov/32777239
Autor:
Alberto A, Gabizon, Esther, Tahover, Talia, Golan, Ravit, Geva, Ruth, Perets, Yasmine, Amitay, Hilary, Shmeeda, Patricia, Ohana
Publikováno v:
Investigational new drugs. 38(5)
Background Pegylated liposomal (PL) mitomycin-c lipidic prodrug MLP) may be a useful agent in patients with metastatic colo-rectal carcinoma (CRC). We report here on the pharmacokinetics and clinical observations in a phase 1A/B study with PL-MLP. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62d34fa4a7fd6256204fb29dc4b2e767
https://pubmed.ncbi.nlm.nih.gov/31955309
https://pubmed.ncbi.nlm.nih.gov/31955309
Autor:
Xiaohui Wei, Yechezkel Barenholz, Patricia Ohana, Yogita Patil, Alberto Gabizon, Yasmine Amitay, Hilary Shmeeda
Publikováno v:
Molecular Pharmaceutics. 14:4339-4345
The effect of a lipidated prodrug of mitomycin C (MLP) on the membrane of a pegylated liposome formulation (PL-MLP), also known as Promitil, was characterized through high-sensitivity differential scanning calorimetry (DSC) and cryo-TEM. The thermody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab0229ae3d412297982644400bcace8
https://doi.org/10.1021/acs.molpharmaceut.6b00865
https://doi.org/10.1021/acs.molpharmaceut.6b00865
Autor:
Esben Christensen, Yasmine Amitay, Jonas Rosager Henriksen, Alberto Gabizon, Thomas Lars Andresen, Andreas Kjaer, Jesper Tranekjær Jørgensen, Anders Elias Hansen, Hilary Schmeeda
Publikováno v:
Christensen, E, Henriksen, J R, Jorgensen, J T, Amitay, Y, Shmeeda, H, Gabizon, A A, Kjaer, A, Andresen, T L & Hansen, A E 2018, ' Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts ', International Journal of Nanomedicine, vol. 13, pp. 7647-7656 . https://doi.org/10.2147/IJN.S182579
Christensen, E, Henriksen, J R, Jørgensen, J T, Amitay, Y, Schmeeda, H, Gabizon, A A, Kjær, A, Andresen, T L & Hansen, A E 2018, ' Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts ', International Journal of Nanomedicine, vol. 13, pp. 7647-7656 . https://doi.org/10.2147/IJN.S182579
International Journal of Nanomedicine
Christensen, E, Henriksen, J R, Jørgensen, J T, Amitay, Y, Schmeeda, H, Gabizon, A A, Kjær, A, Andresen, T L & Hansen, A E 2018, ' Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts ', International Journal of Nanomedicine, vol. 13, pp. 7647-7656 . https://doi.org/10.2147/IJN.S182579
International Journal of Nanomedicine
Esben Christensen,1–3 Jonas R Henriksen,2,4 Jesper T Jørgensen,3 Yasmine Amitay,5 Hilary Shmeeda,5 Alberto A Gabizon,5 Andreas Kjær,3 Thomas L Andresen,1,2 Anders E Hansen1–3 1Department of Micro- and Nanotechnology, DTU Nanotech, Technical Uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fade3dc7c07da645c1c067b7021cde00
https://curis.ku.dk/ws/files/218084314/Folate_receptor_targeting_of_radiolabeled_liposomes_reduces_111718.pdf
https://curis.ku.dk/ws/files/218084314/Folate_receptor_targeting_of_radiolabeled_liposomes_reduces_111718.pdf
Autor:
Patricia Ohana, Yogita Patil, Lidia Mak, Hilary Shmeeda, Alberto Gabizon, Jenny Gorin, Yasmine Amitay, Dina Tzemach
Publikováno v:
Pharmaceutical Research. 33:686-700
Pegylated liposomal (PL) mitomycin C lipid-based prodrug (MLP) has recently entered clinical testing. We studied here the preclinical pharmacology of PL-MLP. The stability, pharmacokinetics, biodistribution, and other pharmacologic parameters of PL-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657f9bb7a802d733255e7636ce30c8c3
https://doi.org/10.1007/s11095-015-1819-7
https://doi.org/10.1007/s11095-015-1819-7
Autor:
Ninh M. La-Beck, Patricia Ohana, Esther Tahover, Hilary Shmeeda, Yasmine Amitay, Alberto Gabizon, Talia Golan, Raanan Berger, Tal Grenader
Publikováno v:
Cancer Medicine
Mitomycin C (MMC) has potent cytotoxicity but cumulative toxicity limits widespread use. In animals, pegylated liposomal mitomycin C lipid-based prodrug (PL-MLP) was well tolerated and more effective than free MMC. We evaluated PL-MLP in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96f6059009d8a51eb530872589e8d82
http://europepmc.org/articles/PMC4618618
http://europepmc.org/articles/PMC4618618