Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yasmina E. Hernandez Santana"'
Autor:
Eirini Giannoudaki, Yasmina E. Hernandez-Santana, Kelly Mulfaul, Sarah L. Doyle, Emily Hams, Padraic G. Fallon, Arimin Mat, Donal O’Shea, Manfred Kopf, Andrew E. Hogan, Patrick T. Walsh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
IL-36α,β and ɣ are IL-1-related cytokines promoting inflammation in the skin and intestine. Here the authors show they are elevated in individuals with obesity, and that mice lacking the IL-36 receptor antagonist are more resistant to diet-induced
Externí odkaz:
https://doaj.org/article/bc1452cbf30c4db3ab7be1abbb926ebf
Autor:
Gemma Leon, Yasmina E. Hernandez Santana, Naoise Irwin, Eirini Giannoudaki, Sadhbh O'Neill, Ilona Csizmadia, Martina Gogarty, Tae J. Lee, Darren Ruane, Aideen Long, Padraic G. Fallon, Seamus Hussey, Patrick T. Walsh
Publikováno v:
Mucosal Immunology. 15:491-503
Autor:
Graeme P. Sullivan, Pavel Davidovich, Natalia Muñoz-Wolf, Ross W. Ward, Yasmina E. Hernandez Santana, Danielle M. Clancy, Aoife Gorman, Zaneta Najda, Boris Turk, Patrick T. Walsh, Ed C. Lavelle, Seamus J. Martin
Publikováno v:
Science immunology. 7(78)
Interleukin-1 (IL-1) family cytokines are key barrier cytokines that are typically expressed as inactive, or partially active, precursors that require proteolysis within their amino termini for activation. IL-37 is an enigmatic member of the IL-1 fam
Autor:
Rachel M. Horan, Shane E. Russell, Padraic G. Fallon, Patrick T. Walsh, Roger S Preston, Cecilia Garlanda, Hazel Lawler, Anna M. Stefanska, Gemma Leon, Eirini Giannoudaki, Yasmina E Hernandez Santana, Cheryl M. Sweeney, Alberto Mantovani, Najma Hassan
Publikováno v:
The Journal of Immunology. 207:651-660
SIGIRR has been described as a negative regulator of several IL-1R/TLR family members and has been implicated in several inflammatory disease conditions. However, it is unknown whether it can suppress IL-36 family cytokines, which are members of the
Publikováno v:
Expert opinion on therapeutic targets. 26(6)
Autor:
Yasmina E Hernandez-Santana, Eduardo Ontoria, Ana C Gonzalez-García, M Antonieta Quispe-Ricalde, Vicente Larraga, Basilio Valladares, Emma Carmelo
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163219 (2016)
The interaction of Leishmania with BALB/c mice induces dramatic changes in transcriptome patterns in the parasite, but also in the target organs (spleen, liver…) due to its response against infection. Real-time quantitative PCR (qPCR) is an interes
Externí odkaz:
https://doaj.org/article/03516f87e6594d27bbd564cdb8bf4ae6
Publikováno v:
Cytokine. 154
The interleukin-1 (IL-1) family of cytokines and receptors are implicated in the functioning of innate and adaptive immunity and the genesis of inflammation. They are widely expressed in structural and immune cells with marked expression within barri
Autor:
Eirini Giannoudaki, Anna M. Stefanska, Hazel Lawler, Gemma Leon, Yasmina E. Hernandez Santana, Najma Hassan, Shane E. Russell, Rachel Horan, Cheryl Sweeney, Roger S. Preston, Alberto Mantovani, Cecilia Garlanda, Padraic G. Fallon, Patrick T. Walsh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(11)
Autor:
Arimin Mat, Manfred Kopf, Sarah L. Doyle, Andrew E. Hogan, Kelly Mulfaul, Yasmina E. Hernandez-Santana, Donal O'Shea, Eirini Giannoudaki, Emily Hams, Padraic G. Fallon, Patrick T. Walsh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10 (1)
Nature Communications
Nature Communications, 10 (1)
Nature Communications
Members of the interleukin-1 (IL-1) family are important mediators of obesity and metabolic disease and have been described to often play opposing roles. Here we report that the interleukin-36 (IL-36) subfamily can play a protective role against the
Autor:
Gemma, Leon, Yasmina E, Hernandez Santana, Naoise, Irwin, Eirini, Giannoudaki, Sadhbh, O'Neill, Ilona, Csizmadia, Martina, Gogarty, Tae J, Lee, Darren, Ruane, Aideen, Long, Padraic G, Fallon, Seamus, Hussey, Patrick T, Walsh
Publikováno v:
Mucosal immunology. 15(3)
IL-36 cytokines are emerging as potent orchestrators of intestinal inflammation and are being implicated in the pathogenesis of inflammatory bowel diseases (IBD). However, the mechanisms through which these cytokines mediate these effects remain to b