Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yasmina Abdiche"'
Autor:
Sabarinath V. Radhakrishnan, Tim Luetkens, Sandra D. Scherer, Patricia Davis, Erica R. Vander Mause, Michael L. Olson, Sara Yousef, Jens Panse, Yasmina Abdiche, K. David Li, Rodney R. Miles, William Matsui, Alana L. Welm, Djordje Atanackovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
CD229 is expressed on the surface of multiple myeloma cells, as well as B and T lymphocytes. Here, the authors engineer CD229-specific CAR T cells and, using patient samples and mouse models, show that treatment with these cells reduces tumour burden
Externí odkaz:
https://doaj.org/article/4e432057e84c4bb2853dee941535a21e
Autor:
Beatrice Cameron, Tarik Dabdoubi, Laurence Berthou-Soulié, Marie Gagnaire, Isabelle Arnould, Anne Severac, Fabienne Soubrier, Jacqueline Morales, Philip A Leighton, William Harriman, Kathryn Ching, Yasmina Abdiche, Katarina Radošević, Thomas Bouquin
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235815 (2020)
Monoclonal antibodies (mAbs) for therapeutic applications should be as similar to native human antibodies as possible to minimize their immunogenicity in patients. Several transgenic animal platforms are available for the generation of fully human mA
Externí odkaz:
https://doaj.org/article/b3aae057ef3a411694da6d530728276c
Autor:
Yik Andy Yeung, Davide Foletti, Xiaodi Deng, Yasmina Abdiche, Pavel Strop, Jacob Glanville, Steven Pitts, Kevin Lindquist, Purnima D. Sundar, Marina Sirota, Adela Hasa-Moreno, Amber Pham, Jody Melton Witt, Irene Ni, Jaume Pons, David Shelton, Arvind Rajpal, Javier Chaparro-Riggers
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Staphylococcus aureuscan both cause disease in humans and be present with no discernible effect. Here, the authors look in detail at the memory immune response against a protein involved in iron acquisition.
Externí odkaz:
https://doaj.org/article/2761e2c97b344bc6b55beb67dcda4616
Autor:
John C Lin, David Tsao, Paul Barras, Raul A Bastarrachea, Bob Boyd, Joyce Chou, Rodnie Rosete, Hua Long, Alison Forgie, Yasmina Abdiche, Jeanette Dilley, Jennifer Stratton, Carlos Garcia, David L Sloane, Anthony G Comuzzie, Arnon Rosenthal
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1900 (2008)
Loss of function mutations in the receptor tyrosine kinase TrkB pathway resulted in hyperphagia and morbid obesity in human and rodents. Conversely, peripheral or central stimulation of TrkB by its natural ligands BDNF or NT4 reduced body weight and
Externí odkaz:
https://doaj.org/article/6efe3da8a10f430793c6095c8907968a
Autor:
Shahram Salek-Ardakani, John C. Lin, Arvind Rajpal, Eugenia Kraynov, Jeffrey Chou, Jerry D. Clark, Allison Xu, Christopher P. Dillon, Natalija Budimir, Brent Kern, Bart Jessen, Cris Kamperschroer, Sherman M. Chin, Christopher R. Kimberlin, Joyce Chou, HoangKim Nguyen, Yasmina Abdiche, Sawsan Youssef, Amir A. Al-Khami
Supplementary Figure 10 shows the selectivity of sasanlimab binding to human and cynomolgus monkey PD-1 using HEK-293T transiently transfected cells and flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570baa904bc39c4217dce06d7f70f261
https://doi.org/10.1158/1535-7163.22521613.v1
https://doi.org/10.1158/1535-7163.22521613.v1
Autor:
Shahram Salek-Ardakani, John C. Lin, Arvind Rajpal, Eugenia Kraynov, Jeffrey Chou, Jerry D. Clark, Allison Xu, Christopher P. Dillon, Natalija Budimir, Brent Kern, Bart Jessen, Cris Kamperschroer, Sherman M. Chin, Christopher R. Kimberlin, Joyce Chou, HoangKim Nguyen, Yasmina Abdiche, Sawsan Youssef, Amir A. Al-Khami
Development of antagonistic mAbs that specifically target the immune checkpoint receptor, programmed cell death protein-1 (PD-1), is of great interest for cancer immunotherapy. Here, we report the biophysical characteristics and nonclinical antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a605a4f9fbc692ff14dc6e0fb35295da
https://doi.org/10.1158/1535-7163.c.6543064
https://doi.org/10.1158/1535-7163.c.6543064