In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species

Autor: Lauriane Serpa Silva Bosquiroli, Ana Caroline dos Santos Ferreira, Katyuce Souza Farias, Eduarda Carneiro da Costa, Maria de Fátima Cepa Matos, Mônica Cristina Toffoli Kadri, Yasmin Silva Rizk, Flávio Macedo Alves, Renata Trentin Perdomo, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda

Publikováno v: Pharmaceutical Biology, Vol 55, Iss 1, Pp 2285-2291 (2017)

Context: New antileishmanias are needed because of toxicity, high cost and resistance problems associated with available drugs. Nectandra (Lauraceae) produces several classes of compounds but its essential oil has not previously been reported to have

Externí odkaz: https://doaj.org/article/eaee9d74fee84409b8dc25a5ac6cf199

In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii

Autor: Dayane Priscilla de Souza Queiroz, Carlos Alexandre Carollo, Mônica Cristina Toffoli Kadri, Yasmin Silva Rizk, Vanessa Carneiro Pereira de Araujo, Paulo Eduardo de Oliveira Monteiro, Patrik Oening Rodrigues, Elisa Teruya Oshiro, Maria de Fátima Cepa Matos, Carla Cardozo Pinto de Arruda

Publikováno v: Memorias do Instituto Oswaldo Cruz, Iss 0 (2016)

The polar hydroethanolic extract from Selaginella sellowii(SSPHE) has been previously proven active on intracellular amastigotes (in vitro test) and now was tested on hamsters infected with Leishmania (Leishmania) amazonensis (in vivo test). SSPHE su

Externí odkaz: https://doaj.org/article/1e0e765f8c29473398548d8deb94e66e

Amentoflavone isolated from Selaginella sellowii Hieron induces mitochondrial dysfunction in Leishmania amazonensis promastigotes

Autor: Kaique Bertrand Almeida Santos, Marcos A. Vannier-Santos, Tânia Zaverucha-do-Valle, Kátia da Silva Calabrese, Daiana de Jesus Hardoim, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda, Yasmin Silva Rizk, Noemi Nosomi Taniwaki, Fernando Almeida-Souza

Publikováno v: Parasitology International. 86:102458

Leishmaniasis chemotherapy is a bottleneck in disease treatment. Although available, chemotherapy is limited, toxic, painful, and does not lead to parasite clearance, with parasite resistance also being reported. Therefore, new therapeutic options ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f003d3078ae05df4c08353fc3dc7bd3
https://doi.org/10.1016/j.parint.2021.102458

A Triazole Hybrid of Neolignans as a Potential Antileishmanial Agent by Triggering Mitochondrial Dysfunction

Autor: Adriano Cesar de Morais Baroni, Diego B. Carvalho, Daiana de Jesus Hardoim, Carla Cardozo Pinto de Arruda, Tânia Zaverucha do Valle, Yasmin Silva Rizk, Kátia da Silva Calabrese, Celeste da Silva Freitas de Souza, Noemi Nosomi Taniwaki

Publikováno v: Molecules
Volume 25
Issue 1

In the search for new compounds with antileishmanial activity, we synthesized a triazole hybrid analogue of the neolignans grandisin and machilin G (LASQUIM 25), which was previously found highly active against both promastigotes and intracellular am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae0b7ea0abea272ab8bcae93bdffaf2
https://doi.org/10.3390/molecules25010037

In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) amazonensis

Autor: Mônica Cristina Toffoli Kadri, Carla Cardozo Pinto de Arruda, Patrik Oening Rodrigues, Carlos Alexandre Carollo, Alice Fischer, Yasmin Silva Rizk, Marillin de Castro Cunha, Maria Carolina Silva Marques, Maria de Fatima Cepa Matos

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 109, Issue: 8, Pages: 1050-1056, Published: DEC 2014
Memórias do Instituto Oswaldo Cruz., Vol 109, Iss 8, Pp 1050-1056 (2014)
Memórias do Instituto Oswaldo Cruz

This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from this plant (SSHE), as well as of the biflavonoids amentoflavone and robustaflavone, isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314c7423fdd60d9d72d707bb4ed5ed27
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000801050&lng=en&tlng=en