NO protects alveolar type II cells from stretch-induced apoptosis. A novel role for macrophages in the lung

Autor: Yasmin S. Edwards, Leanne M. Sutherland, Andrew W. Murray

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 279:L1236-L1242

We have previously shown that mechanical distortion or stretch of alveolar type II (ATII) cells induces both surfactant release and the induction of apoptosis. We hypothesize that nitric oxide (NO) secreted from alveolar macrophages (AMs) prevents cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ed94b4af1d9893183ec533d38b418
https://doi.org/10.1152/ajplung.2000.279.6.l1236

Activation of Mitogen-activated Protein Kinase by Arachidonic Acid in Rat Liver Epithelial WB Cells by a Protein Kinase C-dependent Mechanism

Autor: Zhi H. Huang, Perry J. Hartfield, Alf Poulos, Yasmin S. Edwards, Deborah Ann Rathjen, Andrew W. Murray, Charles S. T. Hii, A. Ferrante

Publikováno v: Journal of Biological Chemistry. 270:4201-4204

Arachidonic acid (20:4(n-6)), which is released by cells responding to a wide range of stimuli, may play an important role in intracellular signaling. We now report that incubation of WB cells with 20:4(n-6) resulted in the appearance of several tyro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1015853972675faf0f9ed54834678e5a
https://doi.org/10.1074/jbc.270.9.4201

Stretch stimulation: its effects on alveolar type II cell function in the lung

Autor: Yasmin S Edwards

Publikováno v: Comparative biochemistry and physiology. Part A, Molecularintegrative physiology. 129(1)

Mechanical stimuli regulate cell function in much the same way as chemical signals do. This has been studied in various cell types, particularly those with defined mechanical roles. The alveolar type II cell (ATII) cell, which is part of the alveolar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9618a518c78c1dcb8bb428cfe193e5ff
https://pubmed.ncbi.nlm.nih.gov/11369549

Stretch stimulation: Its effects on alveolar type II cell function in the lung

Autor: Leanne M. Sutherland, Andrew W. Murray, Yasmin S. Edwards

Publikováno v: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 126:S31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1a9bba8d165a05df72210a2ce8e483f
https://doi.org/10.1016/s0305-0491(00)80062-0

NO protects alveolar type II cells from stretch-induced apoptosis. A novel role for macrophages in the lung.

Autor: Edwards, Yasmin S., Sutherland, Leanne M.

Publikováno v: American Journal of Physiology: Lung Cellular & Molecular Physiology; Dec2000, Vol. 23 Issue 6, pL1236, 7p, 1 Black and White Photograph, 3 Graphs