Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Yasmin, Husaini"'
Autor:
Yasmin Husaini, Vicky Wang-Wei Tsai, Rakesh Manandhar, Hong Ping Zhang, Ka Ki Michelle Lee-Ng, Hélène Lebhar, Christopher P Marquis, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233846 (2020)
Growth Differentiation Factor-15 (GDF15) is a divergent TGF-beta superfamily cytokine that is overexpressed by most cancers and is induced by anticancer therapy. Transgenic and induced animal models suggest that it protects from cancer development bu
Externí odkaz:
https://doaj.org/article/c03491e8a640495c96e487c633b150be
Autor:
Kanin Salao, Lele Jiang, Hui Li, Vicky W.-W. Tsai, Yasmin Husaini, Paul M. G. Curmi, Louise J. Brown, David A. Brown, Samuel N. Breit
Publikováno v:
Biology Open, Vol 5, Iss 5, Pp 620-630 (2016)
Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendr
Externí odkaz:
https://doaj.org/article/f319230c8c664cfd895040d0dc894b41
Supplementary Data from Cytosine Deaminase-Uracil Phosphoribosyltransferase and Interleukin (IL)-12 and IL-18: A Multimodal Anticancer Interface Marked by Specific Modulation in Serum Cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf917b50ff3276de49c152891f6cccb
https://doi.org/10.1158/1078-0432.22440049.v1
https://doi.org/10.1158/1078-0432.22440049.v1
Purpose: To test the effects of a new combination, cytosine deaminase (CD) + uracil phosphoribosyltransferase (UPRT)–mediated gene-directed enzyme prodrug therapy (GDEPT) with interleukin (IL)-12 and IL-18, on (a) growth of murine prostate and remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40deafae4837238c9b72b6cd6d2fbb05
https://doi.org/10.1158/1078-0432.c.6517426
https://doi.org/10.1158/1078-0432.c.6517426
Autor:
Vicky Wang-Wei Tsai, Laurence Macia, Christine Feinle-Bisset, Rakesh Manandhar, Arne Astrup, Anne Raben, Janne Kunchel Lorenzen, Peter T Schmidt, Fredrik Wiklund, Nancy L Pedersen, Lesley Campbell, Adamandia Kriketos, Aimin Xu, Zhou Pengcheng, Weiping Jia, Paul M G Curmi, Christopher N Angstmann, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Christopher P Marquis, Yasmin Husaini, Christoph Beglinger, Shu Lin, Herbert Herzog, David A Brown, Amanda Sainsbury, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133362 (2015)
The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct
Externí odkaz:
https://doaj.org/article/737ad1ed5f8142afac832eb05e943fb9
Autor:
Yasmin Husaini, Glen P Lockwood, Trung V Nguyen, Vicky Wang-Wei Tsai, Mohammad G Mohammad, Pamela J Russell, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115189 (2015)
The divergent TGF-β superfamily member, macrophage inhibitory cytokine-1 (MIC-1/GDF15), is overexpressed by most cancers, including prostate cancer (PCa). Whilst its circulating levels are linked to cancer outcome, the role MIC-1/GDF15 plays in canc
Externí odkaz:
https://doaj.org/article/2be7ba62d1c4450bbace7239dda15025
Autor:
Vicky Wang-Wei Tsai, Rakesh Manandhar, Sebastian Beck Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Christopher Peter Marquis, Lele Jiang, Yasmin Husaini, Shu Lin, Amanda Sainsbury, Paul E Sawchenko, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100370 (2014)
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) modulates food intake and body weight under physiological and pathological conditions by acting on the hypothalamus and brainstem. When overexpressed in disease, such as in advanced cancer, elevated seru
Externí odkaz:
https://doaj.org/article/5e99da808d224bdbb2047faf1def0d0f
Autor:
Vicky Wang-Wei Tsai, Laurence Macia, Heiko Johnen, Tamara Kuffner, Rakesh Manadhar, Sebastian Beck Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Liyun Wu, Christopher Peter Marquis, Lele Jiang, Yasmin Husaini, Shu Lin, Herbert Herzog, David A Brown, Amanda Sainsbury, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55174 (2013)
The TGF-b superfamily cytokine MIC-1/GDF15 circulates in all humans and when overproduced in cancer leads to anorexia/cachexia, by direct action on brain feeding centres. In these studies we have examined the role of physiologically relevant levels o
Externí odkaz:
https://doaj.org/article/4ebdfbedb0784895822349eac65958ab
Autor:
Yasmin Husaini, Min Ru Qiu, Glen P Lockwood, Xu Wei Luo, Ping Shang, Tamara Kuffner, Vicky Wang-Wei Tsai, Lele Jiang, Pamela J Russell, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43833 (2012)
Macrophage inhibitory cytokine-1 (MIC-1/GDF15), a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa) and its expression is linked to cancer outcome. We have evaluated the effect
Externí odkaz:
https://doaj.org/article/3d7060ec5f124fee97f3961731fdecb7
Publikováno v:
Cell Metabolism. 28:353-368
MIC-1/GDF15 is a stress response cytokine and a distant member of the transforming growth factor beta (TGFb) superfamily, with no close relatives. It acts via a recently identified receptor called glial-derived neurotrophic factor (GDNF) receptor alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616037d11c4d0a312de65c9305bdc2de
https://doi.org/10.1016/j.cmet.2018.07.018
https://doi.org/10.1016/j.cmet.2018.07.018