Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yasin Oduk"'
Autor:
Shinobu Yamaguchi, Randee Sedaka, Chintan Kapadia, Jifeng Huang, Jung-Shan Hsu, Taylor F. Berryhill, Landon Wilson, Stephen Barnes, Caleb Lovelady, Yasin Oduk, Ryan M. Williams, Edgar A. Jaimes, Daniel A. Heller, Takamitsu Saigusa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Rapamycin slows cystogenesis in murine models of polycystic kidney disease (PKD) but failed in clinical trials, potentially due to insufficient drug dosing. To improve drug efficiency without increasing dose, kidney-specific drug delivery ma
Externí odkaz:
https://doaj.org/article/280c5588929545ad941f6861d8fa44d3
Autor:
Andrew E. Pollard, Ramaswamy Kannappan, Saidulu Mattapally, Jianyi Zhang, Vladimir G. Fast, Ying Ge, Ling Gao, Anton V. Borovjagin, Gregory P. Walcott, Xinyang Hu, Wuqiang Zhu, Xi Lou, Zachery R. Gregorich, Steven G. Lloyd, Yasin Oduk
Publikováno v:
Circulation. 137:1712-1730
Background: Here, we generated human cardiac muscle patches (hCMPs) of clinically relevant dimensions (4 cm × 2 cm × 1.25 mm) by suspending cardiomyocytes, smooth muscle cells, and endothelial cells that had been differentiated from human induced-p
Autor:
Jianyi Zhang, Yawen Tang, Mani T. Valarmathi, Yasin Oduk, Gregory P. Walcott, Chengming Fan, Danielle Pretorius, Prasanna Krishnamurthy, Wuqiang Zhu, Jinfu Yang, Xi Lou, Philippe Menasché, Meng Zhao
Publikováno v:
JCI Insight
The mortality of patients suffering from acute myocardial infarction is linearly related to the infarct size. As regeneration of cardiomyocytes from cardiac progenitor cells is minimal in the mammalian adult heart, we have explored a new therapeutic
Abstract 17122: Cardioprotection With Proangiogenic Nanomaterials Formulated With CHIR99021 and FGF1
Autor:
Chengming Fan, Yasin Oduk, Meng Zhao, Yawen Tang, Gregory P. Walcott, Jianyi Zhang, Wuqiang Zhu
Publikováno v:
Circulation. 138
Introduction: We aimed at to investigate whether activation of both FGF1 and Wnt1 synergistically enhances angiogenesis and render the cardioprotection in hearts with post infarction LV remodeling. Materials and methods: CHIR99021 (a Wnt1 activator)
Autor:
Yasin Oduk, Anton V. Borovjagin, Lufang Zhou, Meng Zhao, Hanxi Zhu, Saidulu Mattapally, Chengming Fan, Jianyi Zhang, Patrick Ernst, Wuqiang Zhu, Yawen Tang
Publikováno v:
Cardiovascular research. 115(2)
AIMS : The effectiveness of cell-based treatments for regenerative myocardial therapy is limited by low rates of cell engraftment. Y-27632 inhibits Rho-associated protein kinase (ROCK), which regulates the cytoskeletal changes associated with cell ad
Autor:
Yasin Oduk, Suzanne Oparil, Ramaswamy Kannappan, Wuqiang Zhu, Meng Zhao, Anton V. Borovjagin, Jianyi Jay Zhang
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 314(2)
Vascular endothelial growth factor (VEGF) is a well-characterized proangiogenic cytokine that has been shown to promote neovascularization in hearts of patients with ischemic heart disease but can also lead to adverse effects depending on the dose an