Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yasin Ilkagan Tepeli"'
Publikováno v:
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Vol 10, Iss 3, Pp 1567-1577 (2022)
A gene is considered essential if its function is indispensable for the viability or reproductive success of a cell or an organism. Distinguishing essential genes from non-essential ones is a fundamental question in genetics, and it is key to underst
Externí odkaz:
https://doaj.org/article/f71d776e94ea4253b5fe85268c09c291
Publikováno v:
Bioinformatics. 36:5237-5246
Motivation Accurate classification of patients into molecular subgroups is critical for the development of effective therapeutics and for deciphering what drives these subgroups to cancer. The availability of multiomics data catalogs for large cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d0230636da32841cf12be1479729a
https://doi.org/10.1093/bioinformatics/btaa655
https://doi.org/10.1093/bioinformatics/btaa655
Publikováno v:
Delft University of Technology
Motivation Synthetic lethality (SL) between two genes occurs when simultaneous loss of function leads to cell death. This holds great promise for developing anti-cancer therapeutics that target synthetic lethal pairs of endogenously disrupted genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acde8a96dced6a619c02d1441e981f1
https://pubmed.ncbi.nlm.nih.gov/35876858
https://pubmed.ncbi.nlm.nih.gov/35876858