Zobrazeno 1 - 10
of 1 628
pro vyhledávání: '"Yashpal S"'
Autor:
Don W. Coulter, Yashpal S. Chhonker, Devendra Kumar, Varun Kesherwani, Wafaa N. Aldhafiri, Erin M. McIntyre, Gracey Alexander, Sutapa Ray, Shantaram S. Joshi, Rongshi Li, Daryl J. Murry, Nagendra K. Chaturvedi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Medulloblastoma (MB) patients with MYC oncogene amplification or overexpression exhibit extremely poor prognoses and therapy resistance. However, MYC itself has been one of the most challenging targets for cancer treatment. Here,
Externí odkaz:
https://doaj.org/article/1f0fbd593c6a46b394d3ab29ce868b00
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2610 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/260ce32e574941c18c7f0278055bba7f
Autor:
Wafaa N. Aldhafiri, Yashpal S. Chhonker, Nusrat Ahmed, Sandeep K. Singh, Staci L. Haney, James B. Ford, Sarah A. Holstein, Daryl J. Murry
Publikováno v:
Molecules, Vol 29, Iss 18, p 4424 (2024)
A rapid, selective, and sensitive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantitation of MO-OH-Nap tropolone (MO-OH-Nap) in mouse plasma. MO-OH-Nap is an α-substituted tropol
Externí odkaz:
https://doaj.org/article/a3947e3b0236400cbf99b523a869dac5
Autor:
Yashpal S. Chhonker, Wafaa N. Aldhafiri, Dhruvkumar Soni, Neerja Trivedi, Claire Steinbronn, Christine Johnson, Helen C. Stankiewicz Karita, Michael K. Paasche-Orlow, Ruanne Barnabas, Samuel L. Arnold, Daryl J. Murry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a global pandemic of coronavirus disease 2019 (COVID-19). Early in the pandemic, efforts were made to test the SARS-CoV-2 antiviral efficacy of repurposed medications that w
Externí odkaz:
https://doaj.org/article/d9282289d6214c0bb65f9b3353a11d61
Publikováno v:
Viruses, Vol 16, Iss 8, p 1269 (2024)
Applying a pan-astrovirus (AstV) RT-hemi-nested PCR assay, we report here high detection rates (28.3%, 15/53) of AstVs in the small Indian mongoose (Urva auropunctata) on the Caribbean Island of St. Kitts. Based on deduced amino acid (aa) identities
Externí odkaz:
https://doaj.org/article/141a9467e51a44f8b6bcadcd00ea8144
Publikováno v:
Separations, Vol 11, Iss 7, p 197 (2024)
Millions of individuals throughout the world suffer from lymphatic filariasis (LF), which is a morbid disease caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori. These infections belong to tissue-invading nematodes and are one of the ma
Externí odkaz:
https://doaj.org/article/30048d32e5b847ceacc1cf5940cf90dc
Autor:
Claire Steinbronn, Yashpal S. Chhonker, Jenell Stewart, Hannah Leingang, Kate B. Heller, Meighan L. Krows, Michael Paasche‐Orlow, Anna Bershteyn, Helen C. Stankiewicz Karita, Vaidehi Agrawal, Miriam Laufer, Raphael Landovitz, Mark Wener, Daryl J. Murry, Christine Johnston, Ruanne V. Barnabas, Samuel L. M. Arnold
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1243-1257 (2023)
Abstract Hydroxychloroquine (HCQ) is Food and Drug Administration (FDA)‐approved for malaria, systemic and chronic discoid lupus erythematosus, and rheumatoid arthritis. Because HCQ has a proposed multimodal mechanism of action and a well‐establi
Externí odkaz:
https://doaj.org/article/c262333ec9864e1bafb196068bee7040
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d236a51f05a44556a1269ee9464fa374
Autor:
Yashpal S Chhonker, Catherine Bjerum, Veenu Bala, Allassane F Ouattara, Benjamin G Koudou, Toki P Gabo, Abdullah Alshehri, Abdoulaye Meïté, Peter U Fischer, Gary J Weil, Christopher L King, Philip J Budge, Daryl J Murry
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011567 (2023)
Moxidectin (MOX) is a milbemycin endectocide recently approved by the U.S. FDA for the treatment of onchocerciasis in persons at least 12 years of age. MOX has been shown to have a good safety profile in recent clinical trials. The efficacy of MOX fo
Externí odkaz:
https://doaj.org/article/45c8d8f3e90f418f857ef227ccaa3519
Autor:
Abdullah Alshehri, Yashpal S Chhonker, Veenu Bala, Constant Edi, Catherine M Bjerum, Benjamin G Koudou, Lucy N John, Oriol Mitjà, Michael Marks, Christopher L King, Daryl J Murry
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011319 (2023)
BackgroundIvermectin (IVM) is a broad-spectrum anthelmintic drug used to treat diseases caused by filarial worms, such as onchocerciasis and lymphatic filariasis (LF). IVM is part of a triple-drug therapy used by the Mass Drug Administration (MDA) as
Externí odkaz:
https://doaj.org/article/9da492fef0d3471fa97d575993da18c9