Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yashodhan Chinchore"'
Publikováno v:
eLife, Vol 6 (2017)
Vertebrate photoreceptors are among the most metabolically active cells, exhibiting a high rate of ATP consumption. This is coupled with a high anabolic demand, necessitated by the diurnal turnover of a specialized membrane-rich organelle, the outer
Externí odkaz:
https://doaj.org/article/d2e5cbd568674a0eb1cfc16c6b734f07
Publikováno v:
PLoS Genetics, Vol 5, Iss 2, p e1000377 (2009)
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocyt
Externí odkaz:
https://doaj.org/article/45ab9916311b4865be51c6618aa9b5bd
Autor:
Constance L. Cepko, Christelle Guillermeir, Matthew L. Steinhauser, Claudio Punzo, Yashodhan Chinchore, Tedi Begaj
The hereditary nature of many retinal degenerative disorders makes them potentially amenable to corrective gene therapies. Numerous clinical trials are ongoing with the goal to rectify the genetic defect in the afflicted cell types. However, the pers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e506f43913aa3d8f8aeb0b6a2fbbf5c
https://doi.org/10.1101/569665
https://doi.org/10.1101/569665
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Vertebrate photoreceptors are among the most metabolically active cells, exhibiting a high rate of ATP consumption. This is coupled with a high anabolic demand, necessitated by the diurnal turnover of a specialized membrane-rich organelle, the outer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b8950f6e58fda7727437c58b7820e6
https://doi.org/10.7554/elife.25946
https://doi.org/10.7554/elife.25946
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(10)
Photoreceptor cell death accompanying many retinal degenerative disorders results in irreversible loss of vision in humans. However, the precise molecular pathway that executes cell death is not known. Our results from a Drosophila model of retinal d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493f3ce88b7799cd876e7b10d0bef4f7
https://pubmed.ncbi.nlm.nih.gov/22328149
https://pubmed.ncbi.nlm.nih.gov/22328149
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 5, Iss 2, p e1000377 (2009)
PLoS Genetics, Vol 5, Iss 2, p e1000377 (2009)
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa84d42ed2ca389d2fcd41ac06390ab
https://pubmed.ncbi.nlm.nih.gov/19214218
https://pubmed.ncbi.nlm.nih.gov/19214218