Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yashoda Rajpurohit"'
Autor:
Eric J. Small, Gerhardt Attard, Mark Li, Alexander W. Wyatt, Margaret Yu, Angela Lopez-Gitlitz, Brendan Rooney, Deborah S. Ricci, Karen Urtishak, Yashoda Rajpurohit, Felix Y. Feng, Stéphane Oudard, David Olmos, Simon Chowdhury, Michael Gormley, Shibu Thomas, Matthew R. Smith
Purpose:In the placebo-controlled SPARTAN study, apalutamide added to androgen-deprivation therapy (ADT) improved metastasis-free survival, second progression-free survival (PFS2), and overall survival (OS) in patients with nonmetastatic castration-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248297551068419f1162c93269a9877d
https://doi.org/10.1158/1078-0432.c.6530510
https://doi.org/10.1158/1078-0432.c.6530510
Autor:
Eric J. Small, Gerhardt Attard, Mark Li, Alexander W. Wyatt, Margaret Yu, Angela Lopez-Gitlitz, Brendan Rooney, Deborah S. Ricci, Karen Urtishak, Yashoda Rajpurohit, Felix Y. Feng, Stéphane Oudard, David Olmos, Simon Chowdhury, Michael Gormley, Shibu Thomas, Matthew R. Smith
Supplementary Data for Smith et al SPARTAN AR Aberrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04bc1a99e4939913a547111b0f036ea
https://doi.org/10.1158/1078-0432.22480694.v1
https://doi.org/10.1158/1078-0432.22480694.v1
Autor:
Karen Urtishak, Gerhardt Attard, Michael Gormley, Alexander W. Wyatt, Shibu Thomas, Yashoda Rajpurohit, Brendan Rooney, Angela Lopez-Gitlitz, Mark Li, David Olmos, Simon Chowdhury, Eric J. Small, Matthew R. Smith, Margaret K. Yu, Stéphane Oudard, Deborah Ricci, Felix Y. Feng
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(16)
Purpose: In the placebo-controlled SPARTAN study, apalutamide added to androgen-deprivation therapy (ADT) improved metastasis-free survival, second progression-free survival (PFS2), and overall survival (OS) in patients with nonmetastatic castration-
Autor:
Seth Jeffries, Wei-Ting Hwang, Steven M. Albelda, Matthew V. Lorenzi, Charuhas Deshpande, Vinod Krishna, Raluca Verona, Jeffrey C. Thompson, Christiana Davis, Denis Smirnov, Corey J. Langer, Yashoda Rajpurohit
Publikováno v:
Lung Cancer
Objectives Treatment of non-small cell lung cancer (NSCLC) with immune checkpoint blockade (ICB) has resulted in striking clinical responses, but only in a subset of patients. The goal of this study was to evaluate transcriptional signatures previous
Autor:
Mel Pilar Espaillat, Yashoda Rajpurohit, Mike Gormley, Denis Smirnov, Ian McCaffery, Angela Lopez-Gitlitz, Deborah Ricci, Shibu Thomas
Publikováno v:
Cancer Research. 79:1335-1335
Background: The androgen receptor (AR) is a clinically important driver in prostate cancer. In metastatic castration resistant prostate cancer (mCRPC), increased expression of the ligand-independent AR variant 7 (AR-v7) is a biomarker of hormonal the
Autor:
John F. Palma, Haiying Wang, Yixin Wang, Tatiana Vener, C Lisa Kauffman, Doru T Alexandrescu, Carlo Derecho, Yashoda Rajpurohit, Dan P. Hartmann, Timothy Jatkoe
Publikováno v:
Journal of Investigative Dermatology. 130:1887-1892
Diagnosis of cutaneous melanoma requires accurate differentiation of true malignant tumors from highly atypical lesions, which lack the capacity to develop uncontrolled proliferation and to metastasize. We used melanoma markers from previous work to
Autor:
Tatiana Vener, Carlo Derecho, Dondapati Chowdary, Haiying Wang, Georg Schäfer, Shobha Varde, Sebastian Mannweiler, Peter Amersdorfer, Marco Auprich, Howard Robin, Alexandre E. Pelzer, Yashoda Rajpurohit, Jonathan Baden, Joanne Skelton, Bradley C. Leibovich, Abhijit Mazumder, Jyoti Mehrotra, Walt Stallings
Publikováno v:
Clinical Chemistry. 54:874-882
Background: Several studies have demonstrated the value of DNA methylation in urine-based assays for prostate cancer diagnosis. However, a multicenter validation with a clinical prototype has not been published. Methods: We developed a multiplexed, q
Publikováno v:
American Journal of Veterinary Research. 63:1443-1447
Objective—To develop a molecular genetic test to detect the mutant skeletal muscle chloride channel (ClC-1) allele that causes myotonia congenita in Miniature Schnauzers and to analyze the relationship of affected and carrier dogs. Animals—372 Mi
Autor:
Shibu Thomas, Dong Shen, Deborah Ricci, Yashoda Rajpurohit, Michael Gormley, Denis Smirnov, Jaymala Patel
Publikováno v:
Cancer Research. 77:2755-2755
Approximately 28,000 men die from prostate cancer in the US each year. Predictive biomarkers can provide patient risk assessment to enable therapeutic decision making. Compared to tumor, blood based liquid biopsies offer greater flexibility for nonin
Autor:
Timothy Jatkoe, Sandhya Pruthi, Carlo Derecho, Jian Zheng, John Jiang, Yashoda Rajpurohit, Haiying Wang, Matthew J. Ferber, Julian R. Molina, Yixin Wang
Publikováno v:
Molecular and clinical oncology. 1(6)
Circulating tumor cells (CTCs) have recently attracted attention due to their potential as prognostic and predictive markers for the clinical management of metastatic breast cancer patients. The isolation of CTCs from patients may enable the molecula