Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yashiro Koh"'
Autor:
Aran K. Ghosh, Hiroaki Mitsuya, Yuan-Fang Wang, Sandra Gemma, Andrey Kovalevsky, Yashiro Koh, Irene T. Weber, Abigail Baldridge
Publikováno v:
Journal of Medicinal Chemistry. 51:6021-6033
We report the design, synthesis and biological evaluation of a series of novel HIV-1 protease inhibitors. The inhibitors incorporate stereochemically defined flexible cyclic ethers/polyethers as the high affinity P2-ligands. Inhibitors containing sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb66d6fd6c73a43ba7480bc9e071ee9
https://doi.org/10.1021/jm8004543
https://doi.org/10.1021/jm8004543
Autor:
Yashiro Koh, Bruno D. Chapsal, Abigail Baldridge, Kazuhiko Ide, Hiroaki Mitsuya, Arun K. Ghosh
Publikováno v:
Organic letters. 10(22)
The synthesis of a series of stereochemically defined spirocyclic compounds and their use as novel P2-ligands for HIV-1 protease inhibitors are described. The bicyclic core of the ligands was synthesized by an efficient nBu 3SnH-promoted radical cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a3ab24159f6c72ea931c103c502bdb
https://pubmed.ncbi.nlm.nih.gov/18928291
https://pubmed.ncbi.nlm.nih.gov/18928291
Autor:
Hiroaki Mitsuya, Andrey Kovalevsky, Arun K. Ghosh, Abigail Baldridge, Irene T. Weber, Heather B. Miller, Jun Takayama, Sofiya Leshchenko-Yashchuk, Yashiro Koh, Sandra Gemma, Yuan-Fang Wang
Recently, we designed a series of novel HIV-1 protease inhibitors incorporating a stereochemically defined bicyclic fused cyclopentyl (Cp-THF) urethane as the high affinity P2-ligand. Inhibitor 1 with this P2-ligand has shown very impressive potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a90e831426dfceca851333decc6fcf
http://hdl.handle.net/11365/11727
http://hdl.handle.net/11365/11727
Autor:
Oka Ayaka, Kurosaka Hiroshi, Yashiro Kohtaro, Haraguchi Seiji, Lee Donghoon, Aikawa Tomonao, Kogo Mikihiko, Yamashiro Takashi
Publikováno v:
Australasian Orthodontic Journal, Vol 34, Iss 1, Pp 85-93 (2018)
The orthodontic treatment of patients with idiopathic condylar resorption (ICR) remains controversial. The effect of molar intrusion using temporary anchorage devices (TADs) and the consequential gradual counterclockwise rotation of the mandible in p
Externí odkaz:
https://doaj.org/article/153a0f39ea15444b903e5e0a5d2df0a3
Autor:
Arun K. Ghosh, Sandra Gemma, Abigail Baldridge, Yuan-Fang Wang, Andrey Yu. Kovalevsky, Yashiro Koh, Irene T. Weber, Hiroaki Mitsuya
Publikováno v:
Journal of Medicinal Chemistry; Sep2008, Vol. 51 Issue 19, p6021-6033, 13p