Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yashas, Rajendra"'
Autor:
Shababa T. Masoud, Mohammad Jafarnejad, Hoang Nguyen, Buyankhishig Tsogtbaatar, Yashas Rajendra, Alexander Seay, Elliot R. Thomsen, Kensuke Yamanokuchi, Annie Arguello, Meng Fang, Cathal S. Mahon, Pascal Sanchez, Dolo Diaz, Anna Bakardjiev, Kirk Henne
Publikováno v:
Molecular Genetics and Metabolism. 138:107223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf95d87959ec98f4011eeacf9ee0962a
https://doi.org/10.1016/j.ymgme.2022.107223
https://doi.org/10.1016/j.ymgme.2022.107223
Autor:
Ryan J. Watts, Kathryn M. Monroe, Junhua Wang, Melina Lenser, Jennifer Hsiao-Nakamoto, Hoang Nguyen, Todd P. Logan, Do Jin Kim, Fen Huang, Ritesh Ravi, Gilbert Di Paolo, Anil Rana, Kannan Gunasekaran, Yaneth Robles-Colmenares, Gerald M. Cherf, Buyankhishig Tsogtbaatar, Ceyda Llapashtica, Kirk R. Henne, Hilda Solanoy, Pascal E. Sanchez, Yashas Rajendra, Mihalis Kariolis, Ray Lieh Yoon Low, Roni Chau, Laralynne Przybyla, Michelle E. Pizzo, Chi-Lu Chiu, Meng Fang, Anastasia G. Henry, Giuseppe Astarita, Mark S. Dennis, Adam L. Boxer, Sarah L. DeVos, Sonnet S. Davis, Hilary W. Heuer, René Meisner, Joseph W. Lewcock, Devendra B. Srivastava, Bradley F. Boeve, Meredith E. K. Calvert, Katrina W. Lexa, Rachel Prorok, Lukas L. Skuja, Dolores Diaz, Akhil Bhalla, Matthew Simon, Jung H. Suh, Ankita Srivastava, Timothy K. Earr, Howard J. Rosen, Joseph Duque, Bettina Van Lengerich, Elizabeth W. Sun
Publikováno v:
Cell
Cell, vol 184, iss 18
Cell, vol 184, iss 18
GRN mutations cause frontotemporal dementia (GRN-FTD) due to deficiency in progranulin (PGRN), a lysosomal and secreted protein with unclear function. Here, we found that Grn(−/−) mice exhibit a global deficiency in bis(monoacylglycero)phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e8760616b55660b5a69ea73b7ad6da
https://europepmc.org/articles/PMC8489356/
https://europepmc.org/articles/PMC8489356/
Autor:
Hoang Nguyen, Elizabeth Sun, Yashas Rajendra, Gerald Maxwell Cherf, Jennifer Hsiao-Nakamoto, Todd P. Logan, Joseph Duque, Anil Rana, Fen Huang, Matthew J. Simon, Kannan Gunasekaran, Pascal E. Sanchez, Junhua Wang, Mihalis Kariolis, Kirk R. Henne, Zachary Kevin Sweeney, Sofia Mosesova, Sonnet S. Davis, Bettina Van Lengerich, Do Jin Kim, Hai L. Tran, Rachel Prorok, Darren Chan, Mark S. Dennis, Kathryn M. Monroe, Yuda Zhu, Ray Low, Akhil Bhalla, Gilbert Di Paolo, Ankita Srivastava, Giuseppe Astarita, Timothy K. Earr, Joseph W. Lewcock, Roni Chau, Sarah L. DeVos, Ryan J. Watts, Melina Lenser
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f95591018dafb0313abe879816362d9
https://doi.org/10.1002/alz.040602
https://doi.org/10.1002/alz.040602
Publikováno v:
Biotechnology Progress. 33:1393-1400
Most biopharmaceutical drugs, especially monoclonal antibodies (mAbs), bispecific antibodies (BsAbs) and Fc-fusion proteins, are expressed using Chinese Hamster Ovary (CHO) cell lines. CHO cells typically yield high product titers and high product qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0cdeaaacd2a0aff4bf89493c865cea
https://doi.org/10.1002/btpr.2527
https://doi.org/10.1002/btpr.2527
Publikováno v:
Biotechnology Progress. 32:1301-1307
Chinese hamster ovary (CHO) cells remain the default production host for many biopharmaceutical drugs, particularly monoclonal antibodies (mAb). Production of gram and kilogram quantities of protein typically requires the generation of stable CHO clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7562b99c55dc026b1959092d2b405b55
https://doi.org/10.1002/btpr.2307
https://doi.org/10.1002/btpr.2307
Publikováno v:
Biotechnology and Bioengineering. 113:1234-1243
Several naturally occurring vertebrate transposable elements have been genetically modified to enable the transposition of recombinant genes in mammalian cells. We compared three transposons-piggyBac, Tol2, and Sleeping Beauty-for their ability to ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c6738ff03cbf651b802597522fd46a
https://doi.org/10.1002/bit.25888
https://doi.org/10.1002/bit.25888
Autor:
Yashas, Rajendra
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1850
We describe a method for polyethyleneimine (PEI) mediated transient transfection of suspension-adapted Chinese hamster ovary (CHO-DG44) cells for protein expression applicable at scales from 2 mL to 2 L. The method involves transfection at a high cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a3385e643fa99ea5f05a6fa4c834140
https://pubmed.ncbi.nlm.nih.gov/30242678
https://pubmed.ncbi.nlm.nih.gov/30242678
Autor:
Yashas Rajendra
Publikováno v:
Methods in Molecular Biology ISBN: 9781493987290
We describe a method for polyethyleneimine (PEI) mediated transient transfection of suspension-adapted Chinese hamster ovary (CHO-DG44) cells for protein expression applicable at scales from 2 mL to 2 L. The method involves transfection at a high cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f30384f67b705def42b4139433deda5
https://doi.org/10.1007/978-1-4939-8730-6_3
https://doi.org/10.1007/978-1-4939-8730-6_3
Publikováno v:
Biotechnology and Bioengineering. 112:977-986
Transient gene expression (TGE) is a rapid method for the production of recombinant proteins in mammalian cells. While the volumetric productivity of TGE has improved significantly over the past decade, most methods involve extensive cell line engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1505b292d3bd0fb1d4a7d7ecca652da0
https://doi.org/10.1002/bit.25514
https://doi.org/10.1002/bit.25514