Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yash V. Bhagat"'
Autor:
Kristina M. Garske, Asha Kar, Caroline Comenho, Brunilda Balliu, David Z. Pan, Yash V. Bhagat, Gregory Rosenberg, Amogha Koka, Sankha Subhra Das, Zong Miao, Janet S. Sinsheimer, Jaakko Kaprio, Kirsi H. Pietiläinen, Päivi Pajukanta
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Obesity-induced adipose tissue dysfunction can cause low-grade inflammation and downstream obesity comorbidities. Although preadipocytes may contribute to this pro-inflammatory environment, the underlying mechanisms are unclear. We used huma
Externí odkaz:
https://doaj.org/article/3055f5bb90004824b10bd459d9c63909
Autor:
David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
GWAS have identified numerous genetic loci for BMI and related traits. Here, Pan et al. generate Promoter Capture Hi-C data for human white adipocytes and integrate these with data of transcription factor motifs, RNA-seq and GWAS to identify eQTL-eGe
Externí odkaz:
https://doaj.org/article/133629e0a6304f2f8d3499574a04d269
Autor:
David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, Supplementary Table 10 contained incorrect primer sequences for the mobility shift assay for SNP rs4776984. These errors have now been fixed and the corrected version of the Supplementary Information PDF is av
Externí odkaz:
https://doaj.org/article/308b4a5b39644c838965f23043215756
Publikováno v:
Cureus.
Publikováno v:
Cureus.
Publikováno v:
Cureus.
Publikováno v:
Cureus
In this report, we present a case of exacerbation of cold agglutinin syndrome (CAS) potentially due to severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) pneumonia. An 83-year-old female with a history of cold agglutinin hemolytic anemia p
Publikováno v:
Cureus
A 56-year-old male with a history of non-adherence to HIV anti-retroviral therapy (ART) presented with Elsberg syndrome - varicella reactivation causing fever, painful dermatomal rash, weakness of bilateral lower extremities, and urinary and bowel dy
Autor:
Joseph R. Pisegna, Arthur Ko, Minna U. Kaikkonen, Marcus Alvarez, Jihane N. Benhammou, Jussi Pihlajamäki, Kristina M. Garske, David Padua, Dorota Kaminska, Yash V. Bhagat, Päivi Pajukanta, Vesa Kärjä, Carl R. Rankin
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 3, Iss 10, Pp 1356-1372 (2019)
Hepatology Communications, Vol 3, Iss 10, Pp 1356-1372 (2019)
The global obesity epidemic is driving the concomitant rise in nonalcoholic fatty liver disease (NAFLD). To identify new genes involved in central liver functions, we examined liver RNA‐sequence data from 259 patients who underwent morbidly obese b
Autor:
Kirsi H. Pietiläinen, Teresa Tusié-Luna, Miguel Herrera-Hernandez, Brandon Jew, Sini Heinonen, Markku Laakso, Karen L. Mohlke, Eran Halperin, Marcus Alvarez, Elior Rahmani, Carlos A. Aguilar-Salinas, Yash V. Bhagat, Päivi Pajukanta, Linda Liliana Muñoz-Hernandez, Zong Miao, Arthur Ko
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 9, p e1009018 (2020)
PLoS Genetics, Vol 16, Iss 9, p e1009018 (2020)
Reverse causality has made it difficult to establish the causal directions between obesity and prediabetes and obesity and insulin resistance. To disentangle whether obesity causally drives prediabetes and insulin resistance already in non-diabetic i