Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Yash B. Joshi"'
Autor:
Peter E. Clayson, Yash B. Joshi, Michael L. Thomas, Joyce Sprock, John Nungaray, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 6, Iss , Pp 100046- (2022)
Patients with schizophrenia have impairments in early auditory system functioning that relate to clinical, cognitive, and psychosocial functioning. Some neurophysiological biomarkers of auditory information processing are sensitive to and predictive
Externí odkaz:
https://doaj.org/article/de04e0159dc04e088e523d1d3a6b521b
Autor:
Juan L. Molina, Michael L. Thomas, Yash B. Joshi, William C. Hochberger, Daisuke Koshiyama, John A. Nungaray, Lauren Cardoso, Joyce Sprock, David L. Braff, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Cognitive impairments are pervasive and disabling features of schizophrenia. Targeted cognitive training (TCT) is a “bottom-up” cognitive remediation intervention with efficacy for neurocognitive outcomes in schizophrenia, yet individual
Externí odkaz:
https://doaj.org/article/2c39f8ad4f0a4638af9528bc001829f8
Autor:
Daisuke Koshiyama, Makoto Miyakoshi, Kumiko Tanaka-Koshiyama, Yash B. Joshi, Juan L. Molina, Joyce Sprock, David L. Braff, Gregory A. Light
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Background: Patients with schizophrenia show abnormal spontaneous oscillatory activity in scalp-level electroencephalographic (EEG) responses across multiple frequency bands. While oscillations play an essential role in the transmission of informatio
Externí odkaz:
https://doaj.org/article/14cb990c64ba4a559bd799325753c4ec
Autor:
Kumiko Tanaka-Koshiyama, Daisuke Koshiyama, Makoto Miyakoshi, Yash B. Joshi, Juan L. Molina, Joyce Sprock, David L. Braff, Gregory A. Light
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
BackgroundSchizophrenia patients exhibit cognitive deficits across multiple domains, including verbal memory, working memory, and executive function, which substantially contribute to psychosocial disability. Gamma oscillations are associated with a
Externí odkaz:
https://doaj.org/article/1b1e668692584f8082b8572d095fdefc
Autor:
Gregory A. Light, Yash B. Joshi, Juan L. Molina, Savita G. Bhakta, John A. Nungaray, Lauren Cardoso, Juliana E. Kotz, Michael L. Thomas, Neal R. Swerdlow
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 2, Iss , Pp 100012- (2020)
Chronic psychotic disorders, including schizophrenia (SZ), are highly heterogeneous at many levels of analysis, from genetics to clinical presentation and treatment sensitivity. This heterogeneity reflects both a divergence of shared biological pathw
Externí odkaz:
https://doaj.org/article/a65e737d3cb24ee881e64baf6d9fefe4
Autor:
Yash B. Joshi, Gregory A. Light
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to un
Externí odkaz:
https://doaj.org/article/029c1d88dd9e4f6ba79b34108887d92b
Autor:
Yash B. Joshi, Juan L. Molina, David L. Braff, Michael F. Green, Ruben C. Gur, Raquel E. Gur, Keith H. Nuechterlein, William S. Stone, Tiffany A. Greenwood, Laura C. Lazzeroni, Allen D. Radant, Jeremy M. Silverman, Joyce Sprock, Catherine A. Sugar, Debby W. Tsuang, Ming T. Tsuang, Bruce I. Turetsky, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
American Journal of Psychiatry.
Autor:
Yash B, Joshi
Publikováno v:
Current topics in behavioral neurosciences.
Acetylcholine (ACh) signaling is critical for central nervous function and is known to be abnormal in schizophrenia (SZ), a chronic neuropsychiatric disorder in which cognitive deficits persist, despite treatment. This review provides a summary of th
Autor:
Neal R. Swerdlow, Yash B. Joshi, Joyce Sprock, Jo Talledo, Juan L. Molina, Lisa Delano-Wood, Dylan Iwanaga, Juliana E. Kotz, Steven Huege, Gabriel C. Léger, Gregory A. Light
Publikováno v:
Journal of Alzheimer's disease : JAD. 91(1)
Background: The uncompetitive NMDA antagonist, memantine (MEM), enhances prepulse inhibition of startle (PPI) across species. MEM is used to treat Alzheimer’s disease (AD); conceivably, its acute impact on PPI might be used to predict a patient’s
Autor:
Joyce Sprock, Debby W. Tsuang, Raquel E. Gur, Yash B. Joshi, Catherine A. Sugar, Laura C. Lazzeroni, Allen D. Radant, William S. Stone, Neal R. Swerdlow, Ming T. Tsuang, David L. Braff, Keith H. Nuechterlein, Bruce I. Turetsky, Michael F. Green, Juan L. Molina, Laura R MacDonald, Michael L. Thomas, Ruben C. Gur, Gregory A. Light, Tiffany A. Greenwood, Jeremy M. Silverman, John Nungaray
Publikováno v:
Am J Psychiatry
OBJECTIVE: Many psychotropic medications used to treat schizophrenia have significant anticholinergic properties, which are linked to cognitive impairment and dementia risk in healthy subjects. Clarifying the impact of cognitive impairment attributab