Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yaser A. Mostafa"'
Autor:
Asmaa Abo Elgoud Said, Islam M. Abdel-Rahman, Yaser A. Mostafa, Eman Zekry Attia, Mamdouh Nabil Samy, Usama Ramadan Abdelmohsen, Katsuyoshi Matsunami, Mostafa A. Fouad, Yaser G. Gouda
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-10 (2024)
Abstract Bioassay-guided fractionation approach led to identification of two novel compounds; (4-(hydroxymethyl)-3-methoxy-1H-pyrazol (1) and mycalene (2), alongside with four known metabolites; octadecane (3), hexatriacontane (4), 1-heneicosanol (5)
Externí odkaz:
https://doaj.org/article/66b57031db3543c5b74e16b210449b66
Autor:
Yaser A. Mostafa, Jalil Abdeljalil Assoud, Ahmed Y. Desoky, Samy Mohamady, Nesma M. Mohamed, Ola I. A. Salem, Zainab M. Almarhoon, Stefan Bräse, Bahaa G. M. Youssif
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
IntroductionWe developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2.MethodsThe antiproliferative efficacy of the novel targets was assessed against a panel of 60 NCI cancer cell lines
Externí odkaz:
https://doaj.org/article/6cd27a190de540de84af81cc18e46b04
Autor:
Amira M. Mohamed, Ola M. F. Abou-Ghadir, Yaser A. Mostafa, Kholood A. Dahlous, Stefan Bräse, Bahaa G. M. Youssif
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
IntroductionThe combination of BRAF and tyrosine kinase (TK) inhibitors has been demonstrated to be highly effective in inhibiting tumor development and is an approach for overcoming resistance in clinical trials. Accordingly, a novel series of 1,2,4
Externí odkaz:
https://doaj.org/article/98f7a55fc2064da8956fc3521e91be0a
Autor:
Lamya H. Al-Wahaibi, Mohamed A. Mahmoud, Yaser A. Mostafa, Ali E. Raslan, Bahaa G. M. Youssif
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 376-386 (2023)
A new series of piperine-carboximidamide hybrids VIa-k was developed as a new cytotoxic agent targeting EGFR, BRAF, and CDK2. The antiproliferative effect against four cancer cells was investigated against erlotinib. Hybrids VIc, VIf, VIg, VIi, and V
Externí odkaz:
https://doaj.org/article/c559ed5c7e9741fa8b8460f0a015c67a
Autor:
Nourhan Hisham Shady, Sara Khalid Sobhy, Yaser A. Mostafa, Ramadan Yahia, Stefanie P. Glaeser, Peter Kämpfer, Mo’men H. El-Katatny, Usama Ramadan Abdelmohsen
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Endophytic fungi, particularly from higher plants have proven to be a rich source of antimicrobial secondary metabolites. The purpose of this study is to examine the antimicrobial potential of three endophytic fungi Aspergillus sp. SA1, Aspe
Externí odkaz:
https://doaj.org/article/c6be43a2fcfa467f8548975aa7853650
Autor:
Essmat M. El-Sheref, Hendawy N. Tawfeek, Alaa A. Hassan, S. Bräse, Mohammed A. I. Elbastawesy, Hesham A. M. Gomaa, Yaser A. Mostafa, Bahaa G. M. Youssif
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Novel series of amidines were synthesized via the interaction between alicyclic amines, cyclic ketones, and a highly electrophilic 4-azidoquinolin-2(1H)-ones without any catalyst or additive. All the obtained products were elucidated based on NMR spe
Externí odkaz:
https://doaj.org/article/7838b914297c44ca8a909e8ba6e7764a
Autor:
Hendawy N. Tawfeek, Alaa A. Hassan, S. Bräse, M. Nieger, Yaser A. Mostafa, Hesham A.M. Gomaa, Bahaa G.M. Youssif, Essmat M. El-Shreef
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 11, Pp 104280- (2022)
A series of novel thiazolidine-4-one derivatives was synthesized by reacting 1,4-disubstituted hydrazine carbothioamides with diethyl azodicarboxylate. The structures were confirmed by spectroscopic data as well as single-crystal X-ray analyses. The
Externí odkaz:
https://doaj.org/article/c1cf0f9517054a93a50d4eb5a1322099
Autor:
Noha M. Gamaleldin, Hebatallah S. Bahr, Yaser A. Mostafa, Bryant F. McAllister, Amr El Zawily, Che J. Ngwa, Gabriele Pradel, Hossam M. Hassan, Usama Ramadan Abdelmohsen, Dalal Hussien M. Alkhalifah, Wael N. Hozzein
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1631 (2022)
Malaria is a persistent illness with a great public health concern. To combat this fatal disease, developing effective antimalarial medications has become a necessity. In the present study, we described the actinomycetes associated with the Red Sea s
Externí odkaz:
https://doaj.org/article/4e05a89c6bf44ddbb222c8a5194b63dd
Autor:
Lamya H. Al-Wahaibi, Yaser A. Mostafa, Mostafa H. Abdelrahman, Ali H. El-Bahrawy, Laurent Trembleau, Bahaa G. M. Youssif
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 1006 (2022)
The apoptotic antiproliferative actions of our previously reported CB1 allosteric modulators 5-chlorobenzofuran-2-carboxamide derivatives VIIa–j prompted us to develop and synthesise a novel series of indole-2-carboxamide derivatives 5a–k, 6a–c
Externí odkaz:
https://doaj.org/article/8c4cb635c2f942da82b83131a57bd536
Autor:
Nourhan Hisham Shady, Raya Soltane, Sherif A. Maher, Entesar Ali Saber, Mahmoud A. Elrehany, Yaser A. Mostafa, Ahmed M. Sayed, Usama Ramadan Abdelmohsen
Publikováno v:
Plants, Vol 11, Iss 11, p 1392 (2022)
LC-HRMS-assisted chemical profiling of Zizyphus mauritiana fruit extract (ZFE) led to the dereplication of 28 metabolites. Furthermore, wound healing activity of ZFE in 24 adult male New Zealand Dutch strain albino rabbits was investigated in-vivo su
Externí odkaz:
https://doaj.org/article/50d4b59b14f149ca8a0435e8d21347ce