Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasemin van Heuvel"'
Autor:
Yasemin van Heuvel, Stefanie Schatz, Marc Hein, Tanya Dogra, Daniel Kazenmaier, Natalie Tschorn, Yvonne Genzel, Jörn Stitz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
To date, the establishment of high-titer stable viral packaging cells (VPCs) at large scale for gene therapeutic applications is very time- and cost-intensive. Here we report the establishment of three human suspension 293-F-derived ecotropic MLV-bas
Externí odkaz:
https://doaj.org/article/8c77412358714224822d96c752627bca
Publikováno v:
Toxins, Vol 14, Iss 2, p 138 (2022)
Different mechanisms mediate the toxicity of RNA. Genomic retroviral mRNA hijacks infected host cell factors to enable virus replication. The viral genomic RNA of the human immunodeficiency virus (HIV) encompasses nine genes encoding in less than 10
Externí odkaz:
https://doaj.org/article/5c7d361651e4436ab2ca69930536b16d
Publikováno v:
Molecular biotechnology.
The use of two-component transposon plasmid vector systems, namely, a transposase construct and a donor vector carrying the gene of interest (GOI) can accelerate the development of recombinant cell lines. However, the undesired stable transfection of
Publikováno v:
Journal of virological methods. 297
Retroviral vectors derived from murine leukemia virus (MLV) are amongst the most frequently utilized vectors in gene therapy approaches such as the genetic modification of hematopoietic cells. Currently, vector particles are mostly produced employing
Autor:
Tim Clarner, Christian Beißel, Anand Goswami, Felix Fischbach, Christoph Schmitz, Patrizia Leopold, Marion Victor, Cordian Beyer, Tanja Hochstrasser, Yasemin van Heuvel, Lara Nellessen, Joachim Weis, Jiangshan Zhan, Julia Nedelcu, Stella Nyamoya, Bernd Denecke, Markus Kipp
Publikováno v:
Glia. 67(2)
Oligodendrocytes are integral to efficient neuronal signaling. Loss of myelinating oligodendrocytes is a central feature of many neurological diseases, including multiple sclerosis (MS). The results of neuropathological studies suggest that oligodend
Autor:
Annageldi Tayyrov, Andreas Essig, Anja Kombrink, Pauli T. Kallio, Natalia Dürig, John Hintze, Sebastian Micheller, Markus Aebi, Yasemin van Heuvel, Markus Künzler, Chia-Wei Lin, Martina Stöckli
Publikováno v:
The ISME Journal
Bacteria are the main nutritional competitors of saprophytic fungi during colonization of their ecological niches. This competition involves the mutual secretion of antimicrobials that kill or inhibit the growth of the competitor. Over the last years
Autor:
Pauli T. Kallio, Andreas Essig, Susanne Thomann, Paola Venier, Marco Franzoi, Nadia Schürch, Yasemin van Heuvel
Publikováno v:
Biochemistry. 56(37)
Defensins make up a class of cysteine-rich antimicrobial peptides, expressed by virtually all eukaryotes as part of their innate immune response. Because of their unique mode of action and rapid killing of pathogenic microbes, defensins are considere
Autor:
Moritz Daniel, Markus Kipp, Johannes Goldberg, Yasemin van Heuvel, Tim Clarner, Cordian Beyer, Marion Victor
Publikováno v:
Cellular and Molecular Neurobiology. 33:1087-1098
Cuprizone [bis(cyclohexylidenehydrazide)]-induced toxic demyelination is an experimental approach frequently used to study de- and re-myelination in the central nervous system. In this model, mice are fed with the copper chelator cuprizone which lead