Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yasemin Sancak"'
Autor:
Timothy M. Locke, Rose Fields, Hayden Gizinski, George M. Otto, Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Peixian He, David M. Shechner, Chris D. McGann, Matthew D. Berg, Judit Villen, Yasemin Sancak, Devin K. Schweppe
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114879- (2024)
Summary: Calcium ions play important roles in nearly every biological process, yet whole-proteome analysis of calcium effectors has been hindered by a lack of high-throughput, unbiased, and quantitative methods to identify protein-calcium engagement.
Externí odkaz:
https://doaj.org/article/83058aefa024485bafa97ed7f25ab95d
Autor:
Juan Jesus Vicente, Kainat Khan, Grant Tillinghast, José L. McFaline-Figueroa, Yasemin Sancak, Nephi Stella
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Microtubule targeting agents (MTAs) are commonly prescribed to treat cancers and predominantly kill cancer cells in mitosis. Significantly, some MTA-treated cancer cells escape death in mitosis, exit mitosis and become malignant polyploid gi
Externí odkaz:
https://doaj.org/article/deafb19afc12476097f2997a23be0b83
Autor:
Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Henok Ermias, Timothy M. Locke, Hayden E. Gizinski, Joseph P. Dexter, Yasemin Sancak
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106146- (2023)
Summary: Activation of myosin light chain kinase (MLCK) by calcium ions (Ca2+) and calmodulin (CaM) plays an important role in numerous cellular functions including vascular smooth muscle contraction and cellular motility. Despite extensive biochemic
Externí odkaz:
https://doaj.org/article/dfa9997666004496bd94070810bacbc7
Autor:
Enrique Balderas, David R. Eberhardt, Sandra Lee, John M. Pleinis, Salah Sommakia, Anthony M. Balynas, Xue Yin, Mitchell C. Parker, Colin T. Maguire, Scott Cho, Marta W. Szulik, Anna Bakhtina, Ryan D. Bia, Marisa W. Friederich, Timothy M. Locke, Johan L. K. Van Hove, Stavros G. Drakos, Yasemin Sancak, Martin Tristani-Firouzi, Sarah Franklin, Aylin R. Rodan, Dipayan Chaudhuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mitochondrial complex I deficiency is frequent in congenital, neurologic and cardiovascular disease. Here the authors demonstrate that Complex I stimulates the turnover of a mitochondrial calcium channel, which becomes stabilized during Complex I def
Externí odkaz:
https://doaj.org/article/c2ef9f77a9ef4d22aad9d8b4d27239a7
Autor:
Enrique Balderas, David R. Eberhardt, Sandra Lee, John M. Pleinis, Salah Sommakia, Anthony M. Balynas, Xue Yin, Mitchell C. Parker, Colin T. Maguire, Scott Cho, Marta W. Szulik, Anna Bakhtina, Ryan D. Bia, Marisa W. Friederich, Timothy M. Locke, Johan L. K. Van Hove, Stavros G. Drakos, Yasemin Sancak, Martin Tristani-Firouzi, Sarah Franklin, Aylin R. Rodan, Dipayan Chaudhuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/375509dbb57e4c128813f2aea63a1296
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1364-1375.e5 (2019)
Summary: The mitochondrial calcium uniporter has been proposed to coordinate the organelle’s energetics with calcium signaling. Uniporter current has previously been reported to be extremely high in brown adipose tissue (BAT), yet it remains unknow
Externí odkaz:
https://doaj.org/article/fd04d9da610c4a0f974cd7a87b412fc3
Publikováno v:
eLife, Vol 2 (2013)
Mitochondrial calcium (Ca2+) import is a well-described phenomenon regulating cell survival and ATP production. Of multiple pathways allowing such entry, the mitochondrial Ca2+ uniporter is a highly Ca2+-selective channel complex encoded by several r
Externí odkaz:
https://doaj.org/article/20c976f344884703ae93a37667fdfe32
Autor:
Molly Plovanich, Roman L Bogorad, Yasemin Sancak, Kimberli J Kamer, Laura Strittmatter, Andrew A Li, Hany S Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner, Nathan Taneja, Jonathan Oshea, Victor Koteliansky, Vamsi K Mootha
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55785 (2013)
Mitochondrial calcium uptake is present in nearly all vertebrate tissues and is believed to be critical in shaping calcium signaling, regulating ATP synthesis and controlling cell death. Calcium uptake occurs through a channel called the uniporter th
Externí odkaz:
https://doaj.org/article/a7337a4d9d914019b479cff21e32b7e5
Autor:
Melissa J.S. MacEwen, Yasemin Sancak
Publikováno v:
Biochemical Society Transactions. 51:665-673
Mitochondrial calcium (Ca2+) signaling has long been known to regulate diverse cellular functions, ranging from ATP production via oxidative phosphorylation, to cytoplasmic Ca2+ signaling to apoptosis. Central to mitochondrial Ca2+ signaling is the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba143c6f1c3e7780356c32f2968cb91c
https://doi.org/10.1042/bst20220317
https://doi.org/10.1042/bst20220317
Autor:
Bhargavi Duvvuri, Lauren M. Pachman, Payton Hermanson, Ting Wang, Richard Moore, Dennis Ding-Hwa Wang, Aaron Long, Gabrielle A. Morgan, Stephen Doty, Rong Tian, Yasemin Sancak, Christian Lood
Publikováno v:
Journal of Autoimmunity. 138:103061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056187df02bad757ff80ad845d2902f7
https://doi.org/10.1016/j.jaut.2023.103061
https://doi.org/10.1016/j.jaut.2023.103061