Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Yasar Torres-Yaghi"'
Autor:
Rajesh Pahwa, Stuart H. Isaacson, Gary W. Small, Yasar Torres-Yaghi, Fernando Pagan, Marwan Sabbagh
Publikováno v:
Neurology and Therapy, Vol 11, Iss 4, Pp 1571-1582 (2022)
Abstract Introduction Hallucinations and delusions present with psychosis are debilitating non-motor symptoms of Parkinson’s disease, with a prevalence of up to 50–70% at some point during the course of the disease. Often patients and caregivers
Externí odkaz:
https://doaj.org/article/0d29cac55e9f4247a204d784a34a3963
Autor:
Yasar Torres-Yaghi, Nobutaka Hattori, Olivier Rascol, Yu Nakajima, Shelby M. King, Akihisa Mori, Fernando Pagan
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100224- (2023)
Background: In patients with Parkinson’s Disease (PD), two distinct motor subtypes, tremor dominant (TD) and postural instability and gait difficulty (PIGD), can be differentiated using Unified Parkinson’s Disease Rating Scale (UPDRS) sub-scores.
Externí odkaz:
https://doaj.org/article/37d194e6dc424dd7a3cce9a6f61c24a4
Autor:
Rajesh Pahwa, Stuart H. Isaacson, Gary W. Small, Yasar Torres-Yaghi, Fernando Pagan, Marwan Sabbagh
Publikováno v:
Neurology and Therapy, Vol 12, Iss 5, Pp 1803-1803 (2023)
Externí odkaz:
https://doaj.org/article/63504c91169f425f9c890395721c500e
Autor:
Fernando L. Pagan, Yasar Torres‐Yaghi, Michaeline L. Hebron, Barbara Wilmarth, R. Scott Turner, Sara Matar, Dalila Ferrante, Jaeil Ahn, Charbel Moussa
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Bosutinib, a dual Abelson/Src inhibitor, was investigated in individuals with dementia with Lewy bodies (DLB). Methods A single site, randomized, double‐blind, placebo‐controlled study of the effects of oral bosutinib, 100 m
Externí odkaz:
https://doaj.org/article/003e9803bd3344659874b1f34a070969
Autor:
Bethany Peterson, Melissa Armstrong, Douglas Galasko, James E. Galvin, Jennifer Goldman, David Irwin, Henry Paulson, Daniel Kaufer, James Leverenz, Angela Lunde, Ian G. McKeith, Andrew Siderowf, Angela Taylor, Katherine Amodeo, Matt Barrett, Kimiko Domoto-Reilly, John Duda, Stephen Gomperts, Neill Graff-Radford, Samantha Holden, Lawrence Honig, Daniel Huddleston, Carol Lippa, Irene Litvan, Carol Manning, Karen Marder, Charbel Moussa, Chiadi Onyike, Fernando Pagan, Alexander Pantelyat, Victoria Pelak, Kathleen Poston, Joseph Quinn, Irene Richard, Liana S. Rosenthal, Marwan Sabbagh, Douglas Scharre, Sharon Sha, Holly Shill, Yasar Torres-Yaghi, Tina Christie, Todd Graham, Ian Richards, Mike Koehler, Brad Boeve
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-4 (2019)
Abstract The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator’s meeting was held on December 14, 2017, in New Orleans. The program was established to increase patient access to clinical experts on Lewy
Externí odkaz:
https://doaj.org/article/78d82e5caeeb47d5b89d124143fa80b8
Publikováno v:
Toxins, Vol 12, Iss 11, p 691 (2020)
Sialorrhea, or excessive saliva beyond the margin of the lip, is a common problem in many neurological diseases. Previously, sialorrhea has been underrecognized in Parkinson’s disease (PD) patients. Despite this, many patients rank sialorrhea as on
Externí odkaz:
https://doaj.org/article/e2cb649c59d14e1cbf06316fd71d9b1c
Autor:
Marwan, Sabbagh, Gary W, Small, Stuart H, Isaacson, Yasar, Torres-Yaghi, Fernando, Pagan, Rajesh, Pahwa
Publikováno v:
International Journal of Psychiatry in Clinical Practice. 27:69-81
Dementia due to Parkinson's disease and Alzheimer's disease are associated with behavioural and psychological symptoms, including psychosis. Long-term management presents a challenge for health care providers and caregivers. Symptoms of psychosis inc
Autor:
Yasar, Torres-Yaghi, Amelia, Carwin, Jacob, Carolan, Steven, Nakano, Fahd, Amjad, Fernando, Pagan
Publikováno v:
Neuropsychiatric Disease and Treatment
In addition to the classic motor symptoms of Parkinson’s disease (PD), people with PD frequently experience nonmotor symptoms that can include autonomic dysfunction and neuropsychiatric symptoms such as PD psychosis (PDP). Common patient characteri
Autor:
Yasar Torres-Yaghi, Jaeil Ahn, Clementina Ullman, Charbel Moussa, Timothy L Chiu, Michaeline Hebron, Christian Wolf, Kaluvu Balaraman, Ethan Weatherdon, Alexander A Missner, Fernando Pagan, Alan J. Fowler, Val Duka, Habtom W. Ressom, Wangke Shi, Xiaoguang Liu, Jonathan D Greenzaid
Publikováno v:
Hum Mol Genet
The role of Discoidin Domain Receptors (DDRs) is poorly understood in neurodegeneration. DDRs are upregulated in Alzheimer’s and Parkinson’s disease (PD), and DDRs knockdown reduces neurotoxic protein levels. Here we show that potent and preferen
Autor:
Xiaoguang Liu, Jaeil Ahn, Sanjana Mulki, Dalila Ferrante, Abigail Lawler, Wangke Shi, Xiong Jiang, Muhammad Anjum, Michaeline Hebron, Giuseppe Esposito, J. Nathan Starr, Nadia Yusuf, Yasar Torres-Yaghi, Sara Matar, Raymond Scott Turner, Elizabeth E. Mundel, Frank Berkowitz, Fernando Pagan, Charbel Moussa
Publikováno v:
Annals of Neurology
Objective Preclinical evidence with nilotinib, a US Food and Drug Administration (FDA)-approved drug for leukemia, indicates improvement in Alzheimer's disease phenotypes. We investigated whether nilotinib is safe, and detectable in cerebrospinal flu