Does aerobic exercise reduce NASH and liver fibrosis in patients with non-alcoholic fatty liver disease? A systematic literature review and meta-analysis

Autor: Veera Houttu, Julia Bouts, Yasaman Vali, Joost Daams, Aldo Grefhorst, Max Nieuwdorp, Adriaan G. Holleboom

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

BackgroundExercise is an effective strategy for the prevention and regression of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD), but it is unclear whether it can reduce advanced stages of NAFLD, i.e., steatohepatitis and

Externí odkaz: https://doaj.org/article/73680892769540abbd16d46e9eff9039

Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance

Autor: Katherine Johnson, Peter J. Leary, Olivier Govaere, Matthew J. Barter, Sarah H. Charlton, Simon J. Cockell, Dina Tiniakos, Michalina Zatorska, Pierre Bedossa, M. Julia Brosnan, Jeremy F. Cobbold, Mattias Ekstedt, Guruprasad P. Aithal, Karine Clément, Jörn M. Schattenberg, Jerome Boursier, Vlad Ratziu, Elisabetta Bugianesi, Quentin M. Anstee, Ann K. Daly, James Clark, Heather J. Cordell, Rebecca Darlay, Christopher P. Day, Tim Hardy, Yang-Lin Liu, Fiona Oakley, Jeremy Palmer, Rachel Queen, Kristy Wonders, Patrick M. Bossuyt, Adriaan G. Holleboom, Hadi Zafarmand, Yasaman Vali, Jenny Lee, Karine Clement, Raluca Pais, Detlef Schuppan, Michael Allison, Sergio Rodriguez Cuenca, Vanessa Pellegrinelli, Michele Vacca, Antonio Vidal-Puig, Tuulia Hyötyläinen, Aidan McGlinchey, Matej Orešič, Partho Sen, Jose Mato, Óscar Millet, Jean-Francois Dufour, Stephen Harrison, Stefan Neubauer, Michael Pavlides, Ferenc Mozes, Salma Akhtar, Rajarshi Banerjee, Matt Kelly, Elizabeth Shumbayawonda, Andrea Dennis, Charlotte Erpicum, Manuel Romero-Gomez, Rocío Gallego-Durán, Isabel Fernández, Morten Karsdal, Diana Leeming, Mette Juul Fisker, Elisabeth Erhardtsen, Daniel Rasmussen, Per Qvist, Antonia Sinisi, Estelle Sandt, Maria Manuela Tonini, Maurizio Parola, Chiara Rosso, Fabio Marra, Amalia Gastaldelli, Sven Francque, Stergios Kechagias, Hannele Yki-Järvinen, Kimmo Porthan, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Luca Valenti, Salvatore Petta, Luca Miele, Andreas Geier, Christian Trautwein, Paul Hockings, Phil Newsome, David Wenn, Cecília Maria Pereira Rodrigues, Rémy Hanf, Pierre Chaumat, Christian Rosenquist, Aldo Trylesinski, Pablo Ortiz, Kevin Duffin, Carla Yunis, Melissa Miller, Theresa Tuthill, Judith Ertle, Ramy Younes, Leigh Alexander, Rachel Ostroff, Mette Skalshøi Kjær, Lars Friis Mikkelsen, Clifford Brass, Lori Jennings, Maria-Magdalena Balp, Miljen Martic, Guido Hanauer, Sudha Shankar, Richard Torstenson, Céline Fournier, Richard Ehman, Michael Kalutkiewicz, Kay Pepin, Joel Myers, Diane Shevell, Gideon Ho, Henrik Landgren, Rob Myers, Lynda Doward, Diane Whalley, James Twiss

Publikováno v: JHEP Reports, Vol 4, Iss 2, Pp 100409- (2022)

Background & Aims: Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods: We profiled 2,083 s

Externí odkaz: https://doaj.org/article/bf7c90fd285b4e33a8d02523458d147c

Systematic Review with Meta-Analysis: Diagnostic Accuracy of Pro-C3 for Hepatic Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease

Autor: Anne Linde Mak, Jenny Lee, Anne-Marieke van Dijk, Yasaman Vali, Guruprasad P. Aithal, Jörn M. Schattenberg, Quentin M. Anstee, M. Julia Brosnan, Mohammad Hadi Zafarmand, Dewkoemar Ramsoekh, Stephen A. Harrison, Max Nieuwdorp, Patrick M. Bossuyt, Adriaan G. Holleboom

Publikováno v: Biomedicines, Vol 9, Iss 12, p 1920 (2021)

The prevalence and severity of non-alcoholic fatty liver disease (NAFLD) is increasing, yet adequately validated tests for care paths are limited and non-invasive markers of disease progression are urgently needed. The aim of this work was to summari

Externí odkaz: https://doaj.org/article/650140fd75634937b1944b8b2a9aa833

Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study

Autor: Yasaman Vali, Jenny Lee, Jerome Boursier, Salvatore Petta, Kristy Wonders, Dina Tiniakos, Pierre Bedossa, Andreas Geier, Sven Francque, Mike Allison, Georgios Papatheodoridis, Helena Cortez-Pinto, Raluca Pais, Jean-Francois Dufour, Diana Julie Leeming, Stephen A Harrison, Yu Chen, Jeremy F Cobbold, Michael Pavlides, Adriaan G Holleboom, Hannele Yki-Jarvinen, Javier Crespo, Morten Karsdal, Rachel Ostroff, Mohammad Hadi Zafarmand, Richard Torstenson, Kevin Duffin, Carla Yunis, Clifford Brass, Mattias Ekstedt, Guruprasad P Aithal, Jörn M Schattenberg, Elisabetta Bugianesi, Manuel Romero-Gomez, Vlad Ratziu, Quentin M Anstee, Patrick M Bossuyt

Publikováno v: lancet. Gastroenterology & hepatology. Elsevier Limited
Vali, Yasaman; Lee, Jenny; Boursier, Jerome; Petta, Salvatore; Wonders, Kristy; Tiniakos, Dina; Bedossa, Pierre; Geier, Andreas; Francque, Sven; Allison, Mike; Papatheodoridis, Georgios; Cortez-Pinto, Helena; Pais, Raluca; Dufour, Jean-Francois; Leeming, Diana Julie; Harrison, Stephen A; Chen, Yu; Cobbold, Jeremy F; Pavlides, Michael; Holleboom, Adriaan G; ... (2023). Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study. The lancet. Gastroenterology & hepatology, 8(8), pp. 714-725. Elsevier 10.1016/S2468-1253(23)00017-1

BACKGROUND The reference standard for detecting non-alcoholic steatohepatitis (NASH) and staging fibrosis-liver biopsy-is invasive and resource intensive. Non-invasive biomarkers are urgently needed, but few studies have compared these biomarkers in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5804b97ea21d329f8be39ff3820775
https://pure.amc.nl/en/publications/biomarkers-for-staging-fibrosis-and-nonalcoholic-steatohepatitis-in-nonalcoholic-fatty-liver-disease-the-litmus-project(ec377298-92db-4611-8b8e-8f9f2f3e8216).html

Clinicians’ Perspectives on Barriers and Facilitators for the Adoption of Non-Invasive Liver Tests for NAFLD

Autor: Yasaman Vali, Roel Eijk, Timothy Hicks, William S. Jones, Jana Suklan, Adriaan G. Holleboom, Vlad Ratziu, Miranda W. Langendam, Quentin M. Anstee, Patrick M. M. Bossuyt

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2707
Journal of clinical medicine, 11(10):2707. Multidisciplinary Digital Publishing Institute (MDPI)

(1) Background: Given the high prevalence of non-alcoholic fatty liver disease (NAFLD) and the limitations of liver biopsies, multiple non-invasive tests (NITs) have been developed to identify non-alcoholic fatty liver disease (NAFLD) patients at-ris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7750830f30549feab05c64d07a852b6d
http://www.scopus.com/inward/record.url?scp=85129865465&partnerID=8YFLogxK