Výsledky vyhledávání - "Yasaman Mahdavi-Amiri"

Photoredox-catalysed Hydroaminoalkylation of on-DNA N- Arylamines

Autor: Yasaman Mahdavi-Amiri, Nicole Frias, Adam Csakai, Lisa Marcaurelle, Ryan Hili

An efficient approach to the photoredox-catalysed hydroaminoalkylation between on-DNA secondary N-substituted (hetero)arylamines and vinylarenes has been developed and explored. The methodology was examined with a broad scope of vinylarenes and secon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68e681e1d029e940645a805afa39cf22
https://doi.org/10.26434/chemrxiv-2022-cs7rj

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Single-nucleotide resolution of N6-adenine methylation sites in DNA and RNA by nitrite sequencing

Autor: Yasaman Mahdavi-Amiri, Ryan Hili, Kimberley Chung Kim Chung

Publikováno v: Chemical Science

A single-nucleotide resolution sequencing method of N6-adenine methylation sites in DNA and RNA is described. Using sodium nitrite under acidic conditions, chemoselective deamination of unmethylated adenines readily occurs, without competing deaminat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a762af2ab47df9a069442bb3c4ae13
https://doi.org/10.1039/d0sc03509b

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PhOxi-Seq: Single-Nucleotide Resolution Sequencing of

Autor: Kimberley, Chung Kim Chung, Yasaman, Mahdavi-Amiri, Christopher, Korfmann, Ryan, Hili

Publikováno v: Journal of the American Chemical Society. 144(13)

Chemical modifications regulate the fate and function of cellular RNAs. Newly developed sequencing methods have allowed a deeper understanding of the biological role of RNA modifications; however, the vast majority of post-transcriptional modificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e099244faa275d041d16453073964402
https://pubmed.ncbi.nlm.nih.gov/35316019

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PhOxi-Seq: Single-nucleotide resolution sequencing of N2-methylation at guanosine in RNA by photoredox catalysis

Autor: Kimberley Chung, Yasaman Mahdavi-Amiri, Christopher Korfmann, Ryan Hili

Chemical modifications regulate the fate and function of cellular RNA. Newly developed sequencing methods have allowed a deeper understanding of the biological role of RNA modifications; however, the vast majority of post-transcriptional modification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3588f2113acc0a6771d1072207f53b8f
https://doi.org/10.26434/chemrxiv-2022-nx2gg

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Evolutionary Outcomes of Diversely Functionalized Aptamers Isolated from in Vitro Evolution

Autor: Wayland Yeung, Tristan Tiburcio, Dickson Chen, Yasaman Mahdavi-Amiri, Matina Movahedi, Ryan Hili, Dehui Kong

Publikováno v: ACS Synthetic Biology. 9:43-52

Expanding the chemical diversity of aptamers remains an important thrust in the field in order to increase their functional potential. Previously, our group developed LOOPER, which enables the inco...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::522a93f37bc10a27fa6e4a45ecacad3d
https://doi.org/10.1021/acssynbio.9b00222

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Evolutionary Outcomes of Diversely Functionalized Aptamers Isolated from

Autor: Dehui, Kong, Matina, Movahedi, Yasaman, Mahdavi-Amiri, Wayland, Yeung, Tristan, Tiburcio, Dickson, Chen, Ryan, Hili

Publikováno v: ACS synthetic biology. 9(1)

Expanding the chemical diversity of aptamers remains an important thrust in the field in order to increase their functional potential. Previously, our group developed LOOPER, which enables the incorporation of up to 16 unique modifications throughout

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1b7edd49fa20439024521245dfd2db3
https://pubmed.ncbi.nlm.nih.gov/31774997

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Influence of Linker Length on Ligase-Catalyzed Oligonucleotide Polymerization

Autor: Chun Guo, Yasaman Mahdavi-Amiri, Ryan Hili

Publikováno v: Chembiochem : a European journal of chemical biology. 20(6)

Ligase-catalyzed oligonucleotide polymerization (LOOPER) that enables the sequence-defined generation of DNA with up to 16 different modifications has recently been developed. This approach was used to develop new classes of diversely modified DNA ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2d5082fd4bb2cd0e351dbb31850f6c
https://pubmed.ncbi.nlm.nih.gov/30458067

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