Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.

Autor: Yarwood RE; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Imlach WL; Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.; Department of Physiology, Monash University, Melbourne, VIC 3800, Australia., Lieu T; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Veldhuis NA; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Jensen DD; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Klein Herenbrink C; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Aurelio L; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Cai Z; Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.; Department of Physiology, Monash University, Melbourne, VIC 3800, Australia., Christie MJ; Discipline of Pharmacology, University of Sydney, Sydney, NSW 2006, Australia., Poole DP; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia.; Department of Anatomy and Cell Biology, University of Melbourne, Parkville, VIC 3010, Australia., Porter CJH; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., McLean P; Takeda Pharmaceuticals Inc., Cambridge, MA 02139., Hicks GA; Takeda Pharmaceuticals Inc., Cambridge, MA 02139., Geppetti P; Department of Health Sciences, Clinical Pharmacology Unit, University of Florence, 50139 Florence, Italy., Halls ML; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Canals M; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia; meri.canals@monash.edu nb2733@cumc.columbia.edu.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia., Bunnett NW; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia; meri.canals@monash.edu nb2733@cumc.columbia.edu.; The Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC 3052, Australia.; Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Surgery, Columbia University, New York, NY 10032.; Department of Pharmacology, Columbia University, New York, NY 10032.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Nov 14; Vol. 114 (46), pp. 12309-12314. Date of Electronic Publication: 2017 Oct 30.

Hypervigilance, Allostatic Load, and Migraine Prevention: Antibodies to CGRP or Receptor.

Autor: Blumenfeld, Andrew¹ (AUTHOR) andrew.blumenfeld@neurocenter.com, Durham, Paul L.² (AUTHOR), Feoktistov, Alexander³ (AUTHOR), Hay, Debbie L.^4,5 (AUTHOR), Russo, Andrew F.^6,7 (AUTHOR), Turner, Ira⁸ (AUTHOR)

Publikováno v: Neurology & Therapy. Dec2021, Vol. 10 Issue 2, p469-497. 29p.

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells.

Autor: Clark, Ashley J.¹, Mullooly, Niamh², Safitri, Dewi^1,3, Harris, Matthew¹, de Vries, Tessa⁴, MaassenVanDenBrink, Antoinette⁴, Poyner, David R.⁵, Gianni, Davide², Wigglesworth, Mark⁶, Ladds, Graham¹ grl30@cam.ac.uk

Publikováno v: Communications Biology. 6/23/2021, Vol. 4 Issue 1, p1-12. 12p.

Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice.

Autor: Hashikawa-Hobara, Narumi¹ hobara@dls.ous.ac.jp, Mishima, Shuta¹, Okujima, Chihiro¹, Shitanishi, Youdai¹, Hashikawa, Naoya¹

Publikováno v: Scientific Reports. 3/26/2021, Vol. 11 Issue 1, p1-13. 13p.

Current aspects of small extracellular vesicles in pain process and relief.

Autor: Zhang, Lanyu, Liu, Jin, Zhou, Cheng

Publikováno v: Biomaterials Research; 8/10/2023, Vol. 27 Issue 1, p1-30, 30p