Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yaroslava Karpova"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17205 (2023)
Hepatocellular carcinoma (HCC) is a major global health concern, representing one of the leading causes of cancer-related deaths. Despite various treatment options, the prognosis for HCC patients remains poor, emphasizing the need for a deeper unders
Externí odkaz:
https://doaj.org/article/c0cf1cc541cc4787bd1b3886b82905fd
Autor:
Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metasta
Externí odkaz:
https://doaj.org/article/556c762c69cf449d9c1284bce015a7fb
Autor:
Yaroslava Karpova, Sarah J. Johnson, Guillaume Bordet, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113504- (2022)
Post-translational modification of nuclear proteins through the addition of poly(ADP-ribose) (pADPr) moieties is upregulated in many metastatic cancers, where the high levels of pADPr have often been associated with poor cancer prognosis. Although th
Externí odkaz:
https://doaj.org/article/e3c016fa905c4d1898d9dc31800bb1e7
Autor:
Yaroslava Karpova, Danping Guo, Peter Makhov, Adam M. Haines, Dmitriy A. Markov, Vladimir Kolenko, Alexei V. Tulin
Publikováno v:
Cancers, Vol 13, Iss 19, p 4973 (2021)
Poly(ADP-ribose) polymerase 1 (PARP-1) and glycohydrolase (PARG) enzymes regulate chromatin structure, transcription activation, and DNA repair by modulating poly(ADP-ribose) (pADPr) level. Interest in PARP-1 inhibitors has soared recently with the r
Externí odkaz:
https://doaj.org/article/8aa07d5073ad4a49a4c1d827a8f25c5d
Autor:
Yaroslava Karpova, Alexei V. Tulin
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a83180a341e417f731e128b001360a6e
https://doi.org/10.1007/978-1-0716-2891-1_21
https://doi.org/10.1007/978-1-0716-2891-1_21
Autor:
Yaroslava Karpova, Alexei V. Tulin
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26742ae2fb85b0c1044345db5feefc0f
https://doi.org/10.1007/978-1-0716-2891-1_22
https://doi.org/10.1007/978-1-0716-2891-1_22
Autor:
Yaroslava, Karpova, Alexei V, Tulin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2609
Long-branched negatively charged poly(ADP-ribose) (pADPr) is a posttranslation modification of nuclear proteins that play a key role in many chromatin remodeling events. While several enzymes of PARP family could synthesize it across all multicellula
Autor:
Yaroslava, Karpova, Alexei V, Tulin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2609
Members of PARP family are responsible for poly(ADP-ribose) (pADPr) posttranslational modification synthesis. They are intensively studied proteins with more than 20,500 related papers in PubMed database search to date. PARG, the main enzyme that deg
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2609
According to the most recent data, cancer is among the leading cause of death in the United States and accounted for more than 600,000 deaths in 2021. Around 30% of these cancer-related deaths were caused by breast, prostate, and ovarian cancers. PAR
Autor:
Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin
Publikováno v:
BMC cancer. 22(1)
Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metastasis, and