Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yaroslava I. Vernikovska"'
Autor:
Janet M. Wood, Robert A. B. Keates, Joan M. Boggs, Doreen E. Culham, Yaroslava I. Vernikovska, Adam Zuiani
Publikováno v:
Biochemistry. 49:8847-8856
Osmoregulatory transporters stimulate bacterial growth by mediating osmoprotectant uptake in response to increasing osmotic pressure. The ProP protein of Escherichia coli transports proline and other osmoprotectants. Like LacY, ProP is a member of th
Autor:
Janet M. Wood, Doreen E. Culham, Robert A. B. Keates, Joan M. Boggs, Feng Liu, Yaroslava I. Vernikovska
Publikováno v:
Biochemistry. 46:5647-5655
Escherichia coli transporter ProP acts as both an osmosensor and an osmoregulator. As medium osmolality rises, ProP is activated and mediates H+-coupled uptake of osmolytes like proline. A homology model of ProP with 12-transmembrane (TM) helices and
Autor:
Feng Liu, Doreen E. Culham, Robert A. B. Keates, Joan M. Boggs, Yaroslava I. Vernikovska, Janet M. Wood, Alexander Hillar
Publikováno v:
Biochemistry. 44:5634-5646
Transporter ProP of Escherichia coli, a member of the major facilitator superfamily (MFS), acts as an osmosensor and an osmoregulator in cells and after purification and reconstitution in proteoliposomes. H(+)-osmoprotectant symport via ProP is activ
Autor:
James Henderson, Anh Ly, Alexander Hillar, Kathleen I. Racher, Joan M. Boggs, Yaroslava I. Vernikovska, Janet M. Wood, Doreen E. Culham
Publikováno v:
Biochemistry. 42:11815-11823
Transporter ProP of Escherichia coli is an osmosensor and an osmoprotectant transporter. Previous results suggest that medium osmolality determines the proportions of ProP in active and inactive conformations. A cysteine-less (Cys-less) variant was c
Autor:
Robert A. B. Keates, Joan M. Boggs, Natalia Tschowri, Doreen E. Culham, Yaroslava I. Vernikovska, Janet M. Wood
Publikováno v:
Biochemistry. 47(51)
ProP is an osmosensory transporter. The activities of ProP and ProP*, a cysteine-less, His(6)-tagged ProP variant, increase with osmotic pressure in cells and proteoliposomes. In proteoliposomes, ProP activity is osmolality-dependent only if the magn
Publikováno v:
Biochemistry. 44:15636-15636
Membrane transporter ProP from Escherichia coli senses extracellular osmolality and responds by mediating the uptake of osmoprotectants such as glycine betaine when osmolality is high. Earlier EPR and NMR studies showed that a peptide replica of the