Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yaroslav Nikolaev"'
Autor:
Kirill Cherednichenko, Kristina Bardina, Alexandra Vishnevich, Mariia Gablina, Anastasia Gataulina, Yaroslav Nikolaev, Pavel Gushchin, Evgenii Ivanov, Dmitry Kopitsyn, Vladimir Vinokurov
Publikováno v:
Polymers, Vol 15, Iss 21, p 4328 (2023)
The elaboration of a low-cost and effective approach to synthesize hybrid composite materials based on the conventional thermoplastics and natural biopolymers is a sustainable alternative to the production of “traditional” plastics. Cellulose is
Externí odkaz:
https://doaj.org/article/e8f83ae65b344ebf98d6e2d8b2167eb3
Autor:
Ruslan Masharipov, Irina Knyazeva, Yaroslav Nikolaev, Alexander Korotkov, Michael Didur, Denis Cherednichenko, Maxim Kireev
Publikováno v:
Frontiers in Neuroinformatics, Vol 15 (2021)
Classical null hypothesis significance testing is limited to the rejection of the point-null hypothesis; it does not allow the interpretation of non-significant results. This leads to a bias against the null hypothesis. Herein, we discuss statistical
Externí odkaz:
https://doaj.org/article/bb1ad68a0fa34742bb5a7a1707be1a02
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 8, Pp 1-16 (2019)
Abstract Metabolite binding to proteins regulates nearly all cellular processes, but our knowledge of these interactions originates primarily from empirical in vitro studies. Here, we report the first systematic study of interactions between water‐
Externí odkaz:
https://doaj.org/article/4586648bbd6e4aae9d16bfd20a2de217
Autor:
Yaroslav Nikolaev, Christine Deillon, Stefan R K Hoffmann, Laurent Bigler, Sebastian Friess, Renato Zenobi, Konstantin Pervushin, Peter Hunziker, Bernd Gutte
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10765 (2010)
Basic-region leucine zipper (bZIP) proteins are one of the largest transcription factor families that regulate a wide range of cellular functions. Owing to the stability of their coiled coil structure leucine zipper (LZ) domains of bZIP factors are w
Externí odkaz:
https://doaj.org/article/45692af13e28481b9fb07bc0be0f2bd2
Autor:
Markus Blatter, Charlotte Meylan, Antoine Cléry, Roberto Giambruno, Yaroslav Nikolaev, Michel Heidecker, Jessica Arvindbhai Solanki, Manuel O. Diaz, Davide Gabellini, Frédéric H.-T. Allain
Publikováno v:
Science Advances, 9 (16)
Mixed-lineage leukemia 1 (MLL1) is a transcription activator of the HOX family, which binds to specific epigenetic marks on histone H3 through its third plant homeodomain (PHD3) domain. Through an unknown mechanism, MLL1 activity is repressed by cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03131604c531e493919b5477b8954e8
Autor:
Martin Soste, Dominique Kamber, Nadine Dobberstein, Mirjam Zimmermann, Aurelien Rizk, Yuehan Feng, Yaroslav Nikolaev, Nigel Beaton
Publikováno v:
Cancer Research. 83:3847-3847
In drug discovery, target identification (ID) after phenotypic screens is a resource-intensive endeavor aimed to understand compound’s mechanism of action. Target ID for membrane proteins is particularly challenging due to hurdles such as poor prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07a2c643388802333b00bd7a1cd0400c
https://doi.org/10.1158/1538-7445.am2023-3847
https://doi.org/10.1158/1538-7445.am2023-3847
Autor:
Frédéric H.-T. Allain, Yaroslav Nikolaev, Nina Ripin, Dagmar Iber, Martin Soste, Paola Picotti
Publikováno v:
Nature methods
Cellular behavior is controlled by the interplay of diverse biomolecules. Most experimental methods, however, can only monitor a single molecule class or reaction type at a time. We developed an in vitro nuclear magnetic resonance spectroscopy (NMR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10167238259ffca32fc6e02437c5b95
http://europepmc.org/articles/PMC6837886
http://europepmc.org/articles/PMC6837886
Publikováno v:
Applied Soft Computing. 68:162-171
Tracking of signals in Nuclear Magnetic Resonance (NMR) spectra is a basic technique used in drug discovery, systems and structural biology. Current experimental setups allow to measure hundreds of spectra, which require analysis, ideally in an autom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2463ef4bac6ac264655f0a1afcc58879
https://doi.org/10.1016/j.asoc.2018.03.046
https://doi.org/10.1016/j.asoc.2018.03.046
Publikováno v:
Biochemistry. 55:2590-2600
Protein-metabolite interactions play a vital role in the regulation of numerous cellular processes. Consequently, identifying such interactions is a key prerequisite for understanding cellular regulation. However, the noncovalent nature of the bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e59e89bb973d916adba82e7bd280c8e9
https://doi.org/10.1021/acs.biochem.5b01291
https://doi.org/10.1021/acs.biochem.5b01291
Autor:
Ana Paula Oliveira, Patrizia Polverino de Laureto, Paola Picotti, Martin Soste, Abdullah Kahraman, Andre Melnik, Yaroslav Nikolaev, Giorgia De Franceschi, Paul J. Boersema, Yuehan Feng
Publikováno v:
Nature biotechnology
NATURE BIOTECHNOLOGY
NATURE BIOTECHNOLOGY
Changes in protein conformation can affect protein function, but methods to probe these structural changes on a global scale in cells have been lacking. To enable large-scale analyses of protein conformational changes directly in their biological mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abb7145d22c0989532c85236236fbcd