Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Yaron Mosesson"'
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Akademický článek
Divergence and selectivity of expression-coupled histone modifications in budding yeasts.
Autor: Yaron Mosesson, Yoav Voichek, Naama Barkai
Publikováno v: PLoS ONE, Vol 9, Iss 7, p e101538 (2014)
Various histone modifications are widely associated with gene expression, but their functional selectivity at individual genes remains to be characterized. Here, we identify widespread differences between genome-wide patterns of two prominent marks,
Externí odkaz: https://doaj.org/article/7eb5823ce4ee4cff92e9c8a5d16b2514
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2
Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
Autor: Nicole A. Traphagen, Gary N. Schwartz, Steven Tau, Amanda Jiang, Sarah R. Hosford, Abigail E. Goen, Alyssa M. Roberts, Bianca A. Romo, Anneka L. Johnson, Emily-Claire K. Duffy, Eugene Demidenko, Paul Heverly, Yaron Mosesson, Shannon M. Soucy, Fred Kolling, Todd W. Miller
Publikováno v: bioRxiv
PurposeClinical evidence indicates that treatment with estrogens elicits anti-cancer effects in ∼30% of patients with advanced endocrine-resistant estrogen receptor alpha (ER)-positive breast cancer. Despite the proven efficacy of estrogen therapy,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6ad7bfdcd85b16f240bcc6b1b8624a
https://europepmc.org/articles/PMC10055145/
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4
Abstract 854: A pharmaco-pheno-multiomic integration analysis of pancreatic cancer: A highly predictive biomarker model of biomarkers of Gemcitabine/Abraxane sensitivity and resistance
Autor: Gilad Silberberg, Clare Killick-Cole, Yaron Mosesson, Haia Khoury, Xuan Ren, Mara Gilardi, Daniel Ciznadija, Paolo Schiavini, Marianna Zipeto, Michael Ritchie
Publikováno v: Cancer Research. 83:854-854
The overall survival of patients diagnosed with Pancreatic Cancer remains low. Initial responses to current therapeutic interventions are below 50%, leading to a high mortality rate shortly after diagnosis. To date, only a companion diagnostic, non-s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b90ad1dea12b27953a52b11e215b2393
https://doi.org/10.1158/1538-7445.am2023-854
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6
Dynamic lineage priming is driven via direct enhancer regulation by ERK
Autor: Joshua M. Brickman, Teresa E. Knudsen, Yaron Mosesson, Kristina B. Emdal, Rita S. Monteiro, Naama Barkai, Chiara Francavilla, William B. Hamilton, Jesper V. Olsen
Publikováno v: Hamilton, W B, Mosesson, Y, Monteiro, R S, Emdal, K B, Knudsen, T E, Francavilla, C, Barkai, N, Olsen, J V & Brickman, J M 2019, ' Dynamic lineage priming is driven via direct enhancer regulation by ERK ', Nature, vol. 575, pp. 355-360 . https://doi.org/10.1038/s41586-019-1732-z
Hamilton, W B, Mosesson, Y, Monteiro, R S, Emdal, K B, Knudsen, T E, Francavilla, C, Barkai, N, Olsen, J V & Brickman, J M 2019, ' Dynamic lineage priming is driven via direct enhancer regulation by ERK ', Nature, vol. 575, no. 7782, pp. 355-360 . https://doi.org/10.1038/s41586-019-1732-z
Central to understanding cellular behaviour in multi-cellular organisms is the question of how a cell exits one transcriptional state to adopt and eventually become committed to another. Fibroblast growth factor-extracellular signal-regulated kinase
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfaa5add7d8c6570d404b0c4e9f23e0
https://curis.ku.dk/portal/da/publications/dynamic-lineage-priming-is-driven-via-direct-enhancer-regulation-by-erk(440bb80d-9602-46ab-9d10-6d00f67cbd8c).html
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7
Hsp90 restrains ErbB‐2/HER2 signalling by limiting heterodimer formation
Autor: Ami Citri, Yosef Yarden, Judith Gan, János Szöllosi, Yaron Mosesson, Gyorgi Vereb
Publikováno v: EMBO reports. 5:1165-1170
ErbB-2/HER2 is an oncogenic tyrosine kinase that regulates a signalling network by forming ligand-induced heterodimers with several growth factor receptors of the ErbB family. Hsp90 and co-chaperones regulate degradation of ErbB-2 but not other ErbB
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7072345663f17142072b818398525b1
https://doi.org/10.1038/sj.embor.7400300
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8
Polar Expression of ErbB-2/HER2 in Epithelia
Autor: Yaron Mosesson, Ami Citri, Yosef Yarden, Yaara Zwang, Naomi Melamed-Book, Sara Lavi, Maya Shelly, Benjamin Aroeti
Publikováno v: Developmental Cell. 5(3):475-486
ErbB-2/HER2 drives epithelial malignancies by forming heterodimers with growth factor receptors. The primordial invertebrate receptor is sorted to the basolateral epithelial surface by binding of the PDZ domain of Lin-7 to the receptor's tail. We sho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa938e9a864e1b9c37da51dbd43a7f
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9
Ligand-Independent Degradation of Epidermal Growth Factor Receptor Involves Receptor Ubiquitylation and Hgs, an Adaptor Whose Ubiquitin-Interacting Motif Targets Ubiquitylation by Nedd4
Autor: Yossi Machluf, Yaron Mosesson, Liat Yakir, Menachem Katz, Hironobu Asao, Keren Shtiegman, Daniel Harari, Thomas M. Jovin, Pazit Tal-Or, Kazuo Sugamura, Yosef Yarden
Publikováno v: Traffic. 3:740-751
Ligand-dependent endocytosis of the epidermal growth factor receptor (EGFR) involves recruitment of a ubiquitin ligase, and sorting of ubiquitylated receptors to lysosomal degradation. By studying Hgs, a mammalian homolog of a yeast vacuolar-sorting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::447456dbb08db0258b0fffba262b3ca8
https://doi.org/10.1034/j.1600-0854.2002.31006.x
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10
Divergence and selectivity of expression-coupled histone modifications in budding yeasts
Autor: Naama Barkai, Yaron Mosesson, Yoav Voichek
Publikováno v: PLoS ONE, Vol 9, Iss 7, p e101538 (2014)
PLoS ONE
Various histone modifications are widely associated with gene expression, but their functional selectivity at individual genes remains to be characterized. Here, we identify widespread differences between genome-wide patterns of two prominent marks,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59262926438ec64f711ca9baea944110
http://europepmc.org/articles/PMC4090005?pdf=render
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