Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Yarkov Sa"'
1
The first dipeptide ligand of translocator protein: Design and anxiolytic activity
Autor: M. A. Yarkova, Tatiana A Gudasheva, G. V. Mokrov, O. A. Deeva, S. B. Seredenin, Yarkov Sa
Publikováno v: Doklady Biochemistry and Biophysics. 464:290-293
On the basis of the structure of Alpidem, a pyrazolopyrimidine ligand of the translocator protein (TSPO), a dipeptide TSPO ligand, N-carbobenzoxy-L-tryptophanyl-L-isoleucine amide (GD-23), was designed and synthesized using our own original peptide d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52aa49cbea0475b187bb60a6a6873c51
https://doi.org/10.1134/s1607672915050063
Zobrazit plný text záznamu
2
The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities
Autor: Yarkov Sa, Povarnina Py, Tatiana A Gudasheva, Yarkova Ma, S. B. Seredenin
Publikováno v: Acta Naturae
Europe PubMed Central
The translocator protein (TSPO) promotes the translocation of cholesterol to the inner mitochondrial membrane and mediates steroid formation. In this study, we first report on a biological evaluation of the dipeptide GD-23 (N-carbobenzoxy-L tryptopha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0753eb402e5bc7a247de07a2214ef547
https://pubmed.ncbi.nlm.nih.gov/26483966
Zobrazit plný text záznamu
3
Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides
Autor: G. V. Mokrov, O. A. Deeva, Yarkov Sa, T.A. Gudasheva, Yarkova Ma, S.B. Seredenin
Publikováno v: Bioorganicmedicinal chemistry. 23(13)
A series of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides were designed and synthesized as 18 kDa translocator protein (TSPO) ligands. Anxiolytic-like activity of compounds was evaluated in the open field test and elevated plus maze test. Compounds 1a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58573aeb3fe32b84e12ed149eaa422b9
https://pubmed.ncbi.nlm.nih.gov/25937237
Zobrazit plný text záznamu
4
Akademický článek
[PHARMACOLOGICAL STUDY OF NEW COMPOUNDS ACTING AS REGULATORS OF 18-KDA TRANSLOCATOR PROTEIN LIGANDS].
Autor: Yarkov SA, Mokrov GV, Gudasheva TA, Yarkova MA, Seredenin SB
Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2016; Vol. 79 (1), pp. 7-11.
Zobrazit plný text záznamu
5
Akademický článek
The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities.
Autor: Povarnina PY; V.V. Zakusov Research Institute of Pharmacology of RAMS, ul. Baltiyskaya, 8, Moscow, 125315, Russia., Yarkov SA; V.V. Zakusov Research Institute of Pharmacology of RAMS, ul. Baltiyskaya, 8, Moscow, 125315, Russia., Gudasheva TA; V.V. Zakusov Research Institute of Pharmacology of RAMS, ul. Baltiyskaya, 8, Moscow, 125315, Russia., Yarkova MA; V.V. Zakusov Research Institute of Pharmacology of RAMS, ul. Baltiyskaya, 8, Moscow, 125315, Russia., Seredenin SB; V.V. Zakusov Research Institute of Pharmacology of RAMS, ul. Baltiyskaya, 8, Moscow, 125315, Russia.
Publikováno v: Acta naturae [Acta Naturae] 2015 Jul-Sep; Vol. 7 (3), pp. 108-12.
Zobrazit plný text záznamu
6
Akademický článek
Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides.
Autor: Mokrov GV; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia. Electronic address: g.mokrov@gmail.com., Deeva OA; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia., Gudasheva TA; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia., Yarkov SA; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia., Yarkova MA; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia., Seredenin SB; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Baltiyskaya Str., 8, Moscow 125315, Russia.
Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2015 Jul 01; Vol. 23 (13), pp. 3368-78. Date of Electronic Publication: 2015 Apr 23.
Zobrazit plný text záznamu
7
Akademický článek
The first dipeptide ligand of translocator protein: Design and anxiolytic activity.
Autor: Gudasheva TA; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia. tata-sosnovka@mail.ru., Deeva OA; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia., Mokrov GV; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia., Yarkov SA; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia., Yarkova MA; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia., Seredenin SB; Zakusov Research Institute of Pharmacology, ul. Baltiiskaya 8, Moscow, 125315, Russia.
Publikováno v: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2015; Vol. 464, pp. 290-3. Date of Electronic Publication: 2015 Oct 31.
Zobrazit plný text záznamu
8
Akademický článek
Analysis of the Mechanisms of Action of a TSPO Ligand (GML-3 Compound) in a Model of Lipopolysaccharide-Induced Cell Damage.
Autor: Vakhitova, Yu. V.1 (AUTHOR) vakhitova@academpharm.ru, Zainullina, L. F.1 (AUTHOR), Sadovskii, M. S.1 (AUTHOR), Mokrov, G. V.1 (AUTHOR), Seredenin, S. B.1 (AUTHOR)
Publikováno v: Pharmaceutical Chemistry Journal. Aug2022, Vol. 56 Issue 5, p592-596. 5p.
Zobrazit plný text záznamu
9
Akademický článek
Development and Study of Anxiolytic Effect of Gml-1 Tablet Dosage Form.
Autor: Yarkova, M. A.1 (AUTHOR) doctorpharm@mail.ru, Blynskaya, E. V.1 (AUTHOR), Yudina, D. V.1 (AUTHOR), Mokrov, G. V.1 (AUTHOR), Gudasheva, T. A.1 (AUTHOR), Alekseev, K. V.1 (AUTHOR)
Publikováno v: Pharmaceutical Chemistry Journal. Jul2019, Vol. 53 Issue 4, p342-346. 5p.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje