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Publikováno v:
Biospectroscopy. 2:1-8
Amphotericin B (AmB) is a macrolide polyene antibiotic with an asymmetrical distribution of hydrophobic and hydrophilic groups (Fig. 1). Due to this chemical structure AmB is poorly soluble water as well as in many organic solvent [1]. Amphotericin B
Publikováno v:
Spectroscopy of Biological Molecules: New Directions ISBN: 9789401059190
Amphotericin B (AmB) is the drug of choice for many serious systemic fungal infections in immune-compromised individuals, which, owing to AIDS and improved organ transplant immunosupression drugs, are becoming frequent [1]. Unfortunately severe side-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dea17a9183db2b84785002804efd75d
https://doi.org/10.1007/978-94-011-4479-7_222
https://doi.org/10.1007/978-94-011-4479-7_222
Publikováno v:
Pigment cell research. 6(3)
Electron Paramagnetic Resonance (EPR) spectroscopy was employed in the study of the interaction between L-3,4-dihydroxyphenylalanine (L-Dopa) melanin and the cat-ionic porphyrins meso-tetrakis(1-methylpyridinium-4yl)-porphyrin (TMPyP), meso-tetrakis-
Publikováno v:
FEBS Letters. (2-3):283-286
Using surface enhanced Raman spectroscopy (SERS) which enables us to specifically detect traces of monomeric amphotericin B (AmB), we were able to show that in a 10(-5) M AmB suspension, the concentration of free drug was below 10(-8) M in the presen