Výsledky vyhledávání - "Yara Bou Saada"

Akademický článek

A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools

Autor: Diego Germini, Yara Bou Saada, Tatiana Tsfasman, Kristina Osina, Chloé Robin, Nikolay Lomov, Mikhail Rubtsov, Nikolajs Sjakste, Mar≿ Lipinski, Yegor Vassetzky

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 43-50 (2017)

Despite rapid progress, many problems and limitations persist and limit the applicability of gene-editing techniques. Making use of meganucleases, TALENs, or CRISPR/Cas9-based tools requires an initial step of pre-screening to determine the efficienc

Externí odkaz: https://doaj.org/article/75548c5b5bbf4c23b30fe063ceefe615

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Akademický článek

Protective effect of Rhus coriaria fruit extracts against hydrogen peroxide-induced oxidative stress in muscle progenitors and zebrafish embryos

Autor: Fadia Najjar, Francine Rizk, Gilles Carnac, Rim Nassar, Sara Jabak, Anatoly Petrovich Sobolev, Yara Bou Saada, Marwan El Sabban, Aline Hamade

Publikováno v: PeerJ, Vol 5, p e4144 (2017)

Background and Purpose Oxidative stress is involved in normal and pathological functioning of skeletal muscle. Protection of myoblasts from oxidative stress may improve muscle contraction and delay aging. Here we studied the effect of R. coriaria sum

Externí odkaz: https://doaj.org/article/427e6c898f324bcba1620bfb18fffde7

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Effects of cellular senescence on metabolic pathways in non-immune and immune cells

Autor: Yara Bou Saada, Daniela Frasca, Bertrand Friguet, Denisse Garcia

Publikováno v: Mech Ageing Dev

Many cellular stresses induce cellular senescence and the irreversible arrest of cell proliferation in different cell types. Although blocked in their capacity to divide, senescent cells are metabolically active and are characterized by a different m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247a49c2ba796429f65dded1c4d3b5fa
https://doi.org/10.1016/j.mad.2020.111428

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Uncoupling of oxidative phosphorylation and antioxidants affect fusion of primary human myoblasts in vitro

Autor: Vlada V. Zakharova, Boris V. Chernyak, E. N. Popova, Carla Dib, Yara Bou Saada, Yegor S. Vassetzky, Ivan I. Galkin

Publikováno v: Biopolymers and Cell, Vol 32, Iss 2, Pp 111-117 (2016)

Reactive oxygen species are at the origin of muscular fatigue and atrophy. They are also linked to muscular dystrophies, a group of human genetic diseases. Several studies point to the benefits of application of antioxidants and uncouplers of oxidati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6bbbc5b8b3abc1fe0958f80f9548e2
http://biopolymers.org.ua/pdf/32/2/111/

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Correction of the FSHD myoblast differentiation defect by fusion with healthy myoblasts

Autor: Yara Bou Saada, Catherine Richon, Petr Dmitriev, Yegor S. Vassetzky, Marc Lipinski, Dalila Laoudj-Chenivesse, Carla Dib, Gilles Carnac, Philippe Dessen

Publikováno v: Journal of Cellular Physiology. 231:62-71

Facioscapulohumeral dystrophy (FSHD) is a neuromuscular disease with a prevalence that could reach 1 in 8,000 characterized by progressive asymmetric muscle weakness. Myoblasts isolated from FSHD muscles exhibit morphological differentiation defects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3528a990327cabc54dcfa3af0d8244c
https://doi.org/10.1002/jcp.25110

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Protective effect of Rhus coriaria fruit extracts against hydrogen peroxide-induced oxidative stress in muscle progenitors and zebrafish embryos

Autor: Aline Hamade, Rim Nassar, Francine Rizk, Sara Jabak, Marwan El Sabban, Yara Bou Saada, Fadia Najjar, Anatoly Petrovich Sobolev, Gilles Carnac

Publikováno v: PeerJ
PeerJ, Vol 5, p e4144 (2017)
PeerJ, PeerJ, 2017, 5, pp.e4144. ⟨10.7717/peerj.4144⟩
PeerJ 5 (2017): 1–27. doi:10.7717/peerj.4144
info:cnr-pdr/source/autori:Fadia Najjar, Francine Rizk, Gilles Carnac, Rim Nassar, Sara Jabak, Anatoly Petrovich Sobolev, Yara Bou Saada, Marwan El Sabban and Aline Hamade/titolo:Protective effect of Rhus coriaria fruit extracts against hydrogen peroxide-induced oxidative stress in muscle progenitors and zebrafish embryos/doi:10.7717%2Fpeerj.4144/rivista:PeerJ/anno:2017/pagina_da:1/pagina_a:27/intervallo_pagine:1–27/volume:5
PeerJ, 2017, 5, pp.e4144. ⟨10.7717/peerj.4144⟩

Background and PurposeOxidative stress is involved in normal and pathological functioning of skeletal muscle. Protection of myoblasts from oxidative stress may improve muscle contraction and delay aging. Here we studied the effect ofR. coriariasumac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0493b99d78bfded3e4d7466b91a1bff2

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Control of DNA integrity in skeletal muscle under physiological and pathological conditions

Autor: Svetlana Dokudovskaya, Boris V. Chernyak, Yara Bou Saada, Vlada V. Zakharova, Gilles Carnac, Yegor S. Vassetzky, Carla Dib

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2017, 74 (19), pp.3439-3449. ⟨10.1007/s00018-017-2530-0⟩

International audience; Skeletal muscle is a highly oxygen-consuming tissue that ensures body support and movement, as well as nutrient and temperature regulation. DNA damage induced by reactive oxygen species is present in muscles and tends to accum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d848ba80ceeef0928be91dd480aab819
https://pubmed.ncbi.nlm.nih.gov/28444416

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Facioscapulohumeral dystrophy myoblasts efficiently repair moderate levels of oxidative DNA damage

Autor: Yara Bou Saada, Yegor S. Vassetzky, Petr Dmitriev, Marc Lipinski, Dalila Laoudj-Chenivesse, Carla Dib, Gilles Carnac, Aline Hamade

Publikováno v: Histochemistry and Cell Biology
Histochemistry and Cell Biology, Springer Verlag, 2016, 145 (4), pp.475-483. ⟨10.1007/s00418-016-1410-2⟩

Facioscapulohumeral dystrophy (FSHD) is a progressive muscular dystrophy linked to a deletion of a subset of D4Z4 macrosatellite repeats accompanied by a chromatin relaxation of the D4Z4 array on chromosome 4q. In vitro, FSHD primary myoblasts show a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e8869984378c001b6c6263a477a236
https://hal.umontpellier.fr/hal-01803643

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DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients

Autor: Yegor S. Vassetzky, Vlada V. Zakharova, Philippe Dessen, Ruy A. N. Louzada, Carla Dib, Petr Dmitriev, Yara Bou Saada, Aline Hamade, Marc Lipinski, Eugénie Ansseau, Vladimir Lazar, Gilles Carnac, Corinne Dupuy, Thomas Robert, Ana Barat

Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2016, 99, pp.244-258. ⟨10.1016/j.freeradbiomed.2016.08.007⟩

International audience; Facioscapulohumeral dystrophy (FSHD) is one of the three most common muscular dystrophies in the Western world, however, its etiology remains only partially understood. Here, we provide evidence of constitutive DNA damage in i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dd1cb7520b4b9bde4de7877da6df9f
https://pubmed.ncbi.nlm.nih.gov/27519269

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Correction of the FSHD myoblast differentiation defect by fusion with healthy myoblasts

Autor: Carla, Dib, Yara, Bou Saada, Petr, Dmitriev, Catherine, Richon, Philippe, Dessen, Dalila, Laoudj-Chenivesse, Gilles, Carnac, Marc, Lipinski, Yegor S, Vassetzky

Publikováno v: Journal of Cellular Physiology
Journal of Cellular Physiology, Wiley, 2016, 231 (1), pp.62-71. ⟨10.1002/jcp.25110⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b0b93d38e877b421b61bfbb469803306
https://hal.umontpellier.fr/hal-01804854

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