The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer’s Disease and Parkinson’s Disease and Models of Mild Cognitive Impairment

Autor: Karen L.G. Farizatto, Sarah Ruiz, Jeannie Hwang, Morgan C. Pait, Yara Abumohsen, Michael F. Almeida, Katherine M. Rentschler, Ben A. Bahr, Nicole Stumbling Bear, James P. Locklear, Cary Mundell, Kaitlan Smith, Lyndsie H. Elliott, Candice Estick, Uzoma S. Ikonne, Cecily M. Ivey, David Butler

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 18, p 4432 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18

Many neurodegenerative disorders have lysosomal impediments, and the list of proposed treatments targeting lysosomes is growing. We investigated the role of lysosomes in Alzheimer&rsquo
s disease (AD) and other age-related disorders, as well as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c4e747618585efd583ce2ce5ea3697
https://www.mdpi.com/1422-0067/20/18/4432