Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yaqun Zhou"'
Autor:
Longqing Zhang, Xi Tan, Fanhe Song, Danyang Li, Jiayi Wu, Shaojie Gao, Jia Sun, Daiqiang Liu, Yaqun Zhou, Wei Mei
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 687-696 (2024)
[INLINE:1] Activated G-protein-coupled receptor 39 (GPR39) has been shown to attenuate inflammation by interacting with sirtuin 1 (SIRT1) and peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α). However, whether GPR39 attenuates n
Externí odkaz:
https://doaj.org/article/ca49ab450884405cab71986702925e8d
Autor:
Jian Huang, Luxin Wang, Yunli Shen, Shengqi Zhang, Yaqun Zhou, Jimin Du, Xiue Ma, Yi Liu, Dandan Liang, Dan Shi, Honghui Ma, Li Li, Qi Zhang, Yi-Han Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Phosphorylation catalyzed by kinases is a key event in signaling pathways involved in cardiomyocyte hypertrophy. Here the authors show that the kinase CLK4 ameliorates cardiac hypertrophy by phosphorylating NEXN.
Externí odkaz:
https://doaj.org/article/36d9e20912b44883a99753a01abd9262
Autor:
Changhong Lu, Xiao Guo, Xianghui He, Yu Chang, Fa Zheng, Chenji Xu, Shuwen Zhang, Yaqun Zhou, Junfang Li
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 6, Pp 669-678 (2022)
Background: Ischemia reperfusion (I/R) play an imperative role in the expansion of cardiovascular disease. Sinomenine (SM) has been exhibited to possess antioxidant, anticancer, anti-inflammatory, antiviral and anticarcinogenic properties. The aim of
Externí odkaz:
https://doaj.org/article/f74ee67dd49e44889202426ed5f0eab8
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Sorting nexin 17 (SNX17), a member of sorting nexin (SNX) family, acts as a modulator for endocytic recycling of membrane proteins. Results from our previous study demonstrated the embryonic lethality of homozygous defect of SNX17. In this study, we
Externí odkaz:
https://doaj.org/article/807d6f369efa4d01a42ffe4a53ca60cf
Publikováno v:
Brain Sciences, Vol 12, Iss 12, p 1732 (2022)
Sepsis-Associated Encephalopathy (SAE) is common in sepsis patients, with high mortality rates. It is believed that neuroinflammation is an important mechanism involved in SAE. High mobility group box 1 protein (HMGB1), as a late pro-inflammatory fac
Externí odkaz:
https://doaj.org/article/3713382ace3141b780815885b216e266
Autor:
Daiqiang Liu, Yaqun Zhou, Yawen Peng, Peng Su, Zheng Li, Qiaoqiao Xu, Ye Tu, Xuebi Tian, Hui Yang, Zhen Wu, Wei Mei, Feng Gao
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Morphine tolerance remains an intractable problem, which hinders its prolonged use in clinical practice. Endoplasmic reticulum (ER) stress has been proved to play a fundamental role in the pathogenesis of Alzheimer’s disease, diabetes, atherosclero
Externí odkaz:
https://doaj.org/article/f5f82a4e1a5845419b118b43e1238ad8
Publikováno v:
Journal of Neurophysiology. 129:1145-1156
Dex inhibits hippocampal neuroinflammation and attenuates early cognitive impairment by enhancing autophagy following surgery in rats. Dex may protect postoperative cognitive function by activating the LKB1/AMPK/ULK-1 signaling pathway.
Autor:
YaQun, Zhou, Justin, Chin, Abigail, Evangelista, Blake, Podger, Peter J, Wan, Christine M, Lomiguen
Publikováno v:
Cureus.
Total knee arthroplasty (TKA) is a very common surgical treatment approach for severe osteoarthritis. Complications of TKA include loss of range of motion and prolonged analgesic requirement for pain control. Osteopathic manipulative techniques (OMT)
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Dermatofibrosarcoma protuberans (DFSP) is a rare tumor that behaves in a benign manner during its early stages and has a potential for metastasis. • DFSP can occur under previous surgical scars which can mask its development from lac
Publikováno v:
Biochemical and Biophysical Research Communications. 510:97-103
SRPIN340, a selective serine-arginine protein kinase 1/2 (SRPK1/2) inhibitor, has been shown to have antiviral and anti-angiogenesis effects. However, its role in the heart is unknown. The present study explored the role of SRPIN340 in myocardial pro