Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Yaqing Jiao"'
Autor:
Yaqing Jiao, Cindy S. W. Tong, Lingyun Zhao, Yilin Zhang, John M. Nicholls, Timothy H. Rainer
Publikováno v:
Laboratory Animal Research, Vol 40, Iss 1, Pp 1-7 (2024)
Abstract Community-acquired respiratory infection is the commonest cause of sepsis presenting to emergency departments. Yet current experimental animal models simulate peritoneal sepsis with intraperitoneal (I.P.) injection of lipopolysaccharide (LPS
Externí odkaz:
https://doaj.org/article/d91fe190c2a04f89bfea12f86eb0c161
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17770- (2023)
Introduction: Clinicians need reliable outcome predictors to improve the prognosis of septic patients. Mouse models are widely used in sepsis research. We aimed to review how mouse models were used to search for novel prognostic biomarkers of sepsis
Externí odkaz:
https://doaj.org/article/84ef99569fe5456c82e5a90f553a276e
Autor:
Qianyun Li, Lingyun Zhao, Ching Long Chan, Yilin Zhang, See Wai Tong, Xiaodan Zhang, Joshua Wing Kei Ho, Yaqing Jiao, Timothy Hudson Rainer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13821 (2023)
Blood biomarkers hold potential for the early diagnosis of ischaemic stroke (IS). We aimed to evaluate the current weight of evidence and identify potential biomarkers and biological pathways for further investigation. We searched PubMed, EMBASE, the
Externí odkaz:
https://doaj.org/article/77efde0bda084802a449af10df431044
Publikováno v:
Atmospheric Environment: X, Vol 14, Iss , Pp 100175- (2022)
Soil freeze-thaw cycles are associated with nitrous oxide (N2O) emissions, and climate warming changes the freeze-thaw process of permafrost and delays the starting period of soil freezing. However, it remains unclear how freeze-thaw cycles of the au
Externí odkaz:
https://doaj.org/article/9747d769c2bd460ca2cf6ae8c4d480c9
Autor:
Yaqing Jiao, Sarah Preston, Jose F. Garcia-Bustos, Jonathan B. Baell, Sabatino Ventura, Thuy Le, Nicole McNamara, Nghi Nguyen, Antony Botteon, Cameron Skinner, Jill Danne, Sarah Ellis, Anson V. Koehler, Tao Wang, Bill C.H. Chang, Andreas Hofmann, Abdul Jabbar, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 9, Iss , Pp 59-71 (2019)
In the present study, the anthelmintic activity of a human tyrosine kinase inhibitor, AG-1295, and 14 related tetrahydroquinoxaline analogues against Haemonchus contortus was explored. These compounds were screened against parasitic larvae - exsheath
Externí odkaz:
https://doaj.org/article/caac004597e54aa1a78f4bf273595773
Autor:
Sarah Preston, Yaqing Jiao, Jonathan B. Baell, Jennifer Keiser, Simon Crawford, Anson V. Koehler, Tao Wang, Moana M. Simpson, Ray M. Kaplan, Karla J. Cowley, Kaylene J. Simpson, Andreas Hofmann, Abdul Jabbar, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 286-294 (2017)
The discovery and development of novel anthelmintic classes is essential to sustain the control of socioeconomically important parasitic worms of humans and animals. With the aim of offering novel, lead-like scaffolds for drug discovery, Compounds Au
Externí odkaz:
https://doaj.org/article/8ba8ab2468e24449941e1de9e44ab2d5
Autor:
Yaqing Jiao, Sarah Preston, Anson V. Koehler, Andreas J. Stroehlein, Bill C. H. Chang, Kaylene J. Simpson, Karla J. Cowley, Michael J. Palmer, Benoît Laleu, Timothy N. C. Wells, Abdul Jabbar, Robin B. Gasser
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Background In partnership with the Medicines for Malaria Venture (MMV), we screened a collection (‘Stasis Box’) of 400 compounds (which have been in clinical development but have not been approved for illnesses other than neglected infec
Externí odkaz:
https://doaj.org/article/42151eb5042e4f648e96208755c17b05
Autor:
Yaqing Jiao, Sarah Preston, Hongjian Song, Abdul Jabbar, Yuxiu Liu, Jonathan Baell, Andreas Hofmann, Dana Hutchinson, Tao Wang, Anson V. Koehler, Gillian M. Fisher, Katherine T. Andrews, Benoît Laleu, Michael J. Palmer, Jeremy N. Burrows, Timothy N. C. Wells, Qingmin Wang, Robin B. Gasser
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Background In this study, we tested five series of pyrazole-5-carboxamide compounds (n = 55) for activity against parasitic stages of the nematode Haemonchus contortus (barber’s pole worm), one of the most pathogenic parasites of ruminants
Externí odkaz:
https://doaj.org/article/23c9a23e634d4f5fa18d8f7b336a309d
Autor:
Sarah Preston, Yaqing Jiao, Abdul Jabbar, Sean L. McGee, Benoît Laleu, Paul Willis, Timothy N.C. Wells, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 329-334 (2016)
There is a substantial need to develop new medicines against parasitic diseases via public-private partnerships. Based on high throughput phenotypic screens of largely protozoal pathogens and bacteria, the Medicines for Malaria Venture (MMV) has rece
Externí odkaz:
https://doaj.org/article/db3a431160a7488cabe0d23839f5dadc
Publikováno v:
Environmental Science and Pollution Research. 29:31700-31712