Zobrazeno 1 - 10
of 4 621
pro vyhledávání: '"Yap1"'
Autor:
Luca Gelsomino, Amanda Caruso, Emine Tasan, Adele Elisabetta Leonetti, Rocco Malivindi, Giuseppina Daniela Naimo, Francesca Giordano, Salvatore Panza, Guowei Gu, Benedetta Perrone, Cinzia Giordano, Loredana Mauro, Bruno Nardo, Gianfranco Filippelli, Daniela Bonofiglio, Ines Barone, Suzanne A. W. Fuqua, Stefania Catalano, Sebastiano Andò
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Background Endocrine therapy (ET) has improved the clinical outcomes of Estrogen receptor alpha-positive (ERɑ +) breast cancer (BC) patients, even though resistance to ET remains a clinical issue. Mutations in the hormone-binding domain of
Externí odkaz:
https://doaj.org/article/a15205f3fedd411da50e8592ece8c6cf
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Myocardial infarction (MI) remains a significant global health concern, characterized by cardiomyocyte apoptosis and adverse ventricular remodeling. Nevertheless, the interplay between exosomal miR-21-5p and Yes-associated protein
Externí odkaz:
https://doaj.org/article/bfa5f5ce4d7f49448c727442d4d2292a
Autor:
Leiming Wang, Lei Cheng, Yongjuan Fu, Hua Dong, Yanlei Xiong, Dehong Lu, Yueshan Piao, Lianghong Teng
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/f5e30ac4673b4ecfbc9dfd6d20a3532e
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 148771-810 (2024)
Sepsis triggers myocardial injury and dysfunction, leading to a high mortality rate in patients. Cardiomyocyte apoptosis plays a positive regulatory role in septic myocardial injury and dysfunction. However, the mechanism is unclear.
Externí odkaz:
https://doaj.org/article/07d293630b2a460e998f1a20a6041b3d
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 3197-3214 (2024)
Caige Li,1,2 Yu Xue,1 Yiwei Liu,1 Kangning Zheng,1 Yuting Gao,1,3 Yi Gong,1 Junlan Lu,1 Yuman Zhang,1 Jingmin Ji,1 Zhiqin Zhang,1 Xinli Shi1 1Department of Pathobiology and Immunology, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, People
Externí odkaz:
https://doaj.org/article/98a8f6aaf1df4af992dd628129da80c3
Autor:
Lixia Li, Dewei Liu, Tingting Chen, Chunhui Wei, Youping Qiao, Weiliang Liu, Yanmei Liang, Zhu Liang, Chunyuan Chen, Dongming Li, Bin Wu, Xuanna Zhao, Dan Huang, Dong Wu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background The progression of non-small cell lung cancer (NSCLC) is significantly influenced by circular RNAs (circRNAs), especially in tumor hypoxia microenvironment. However, the precise functions and underlying mechanisms of dysregulated
Externí odkaz:
https://doaj.org/article/760dc153586746b181592c6568a22e27
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Depression is a complex mood disorder whose pathogenesis involves multiple cell types and molecular pathways. The prefrontal cortex, as a key brain region for emotional regulation, plays a crucial role in depression. Microglia, as
Externí odkaz:
https://doaj.org/article/9240ae0385f14c39ae068ddaae6e2986
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT High-risk human papillomavirus (HPV) oncoproteins inactivate cellular tumor suppressors to reprogram host cell signaling pathways. HPV E7 proteins bind and degrade the tumor suppressor PTPN14, thereby promoting the nuclear localization of th
Externí odkaz:
https://doaj.org/article/3ac950327bc74d55a5d29001a0f35c0c
Autor:
Osorio Lopes Abath Neto, Leonardo Furtado Freitas, Martha Quezado, Zied Abdullaev, Kenneth Aldape
Publikováno v:
Free Neuropathology, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/65218a6b315b4a65a5eb16f45baa3dba
Autor:
Naoe Jimbo, Chiho Ohbayashi, Tomomi Fujii, Maiko Takeda, Suguru Mitsui, Yugo Tanaka, Tomoo Itoh, Yoshimasa Maniwa
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 5, Pp n/a-n/a (2024)
Abstract Lineage plasticity in small cell lung carcinoma (SCLC) causes therapeutic difficulties. This study aimed to investigate the pathological findings of plasticity in SCLC, focusing on combined SCLC, and elucidate the involvement of YAP1 and oth
Externí odkaz:
https://doaj.org/article/04acd36db1f54c938bb02d76e284c29c