Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Yaozu XIANG"'
Autor:
Baowei Zhang, Yizhang Wu, Chunjiang Zhou, Jiaxi Xie, Youming Zhang, Xingbo Yang, Jing Xiao, Dao Wu Wang, Congjia Shan, Xiujuan Zhou, Yaozu Xiang, Bing Yang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized with progressive cardiac fibrosis and heart failure. However, the exact mechanism driving the progression of cardiac fibrosis and heart failure in AC
Externí odkaz:
https://doaj.org/article/d7914032d6aa4b56bc12cd2bfab1e3a7
Publikováno v:
Pharmacological Research, Vol 205, Iss , Pp 107256- (2024)
Inflammation is a crucial factor in cardiac remodeling after acute myocardial infarction (MI). Neutrophils, as the first wave of leukocytes to infiltrate the injured myocardium, exacerbate inflammation and cardiac injury. However, therapies that depl
Externí odkaz:
https://doaj.org/article/14c03b14486a4b0184464a005282efbf
Autor:
Yixiang Xu, Chao Zhang, Kai Jiang, Xinchun Yang, Feng Chen, Zhiyang Cheng, Jinlong Zhao, Jiaxing Cheng, Xiaokang Li, Xin Chen, Luoyifan Zhou, Hao Duan, Yunyuan Huang, Yaozu Xiang, Jian Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1671-1685 (2023)
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been reapproved for heart failure (HF) therapy in patients with and without diabetes. However, the initial glucose-lowering indication of SGLT2i has impeded their uses in cardiovascular clinical
Externí odkaz:
https://doaj.org/article/cdc0f8d16c074da88208166de8124fc6
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113174- (2023)
Summary: The immune system plays a critical role during myocardial injury, contributing to repair and remodeling post myocardial infarction (MI). The myocardial infarct and border zone exhibit high heterogeneity, in turn leading to reconstructing mac
Externí odkaz:
https://doaj.org/article/41f39bc55ebd47849fd1f0564c8a1bf5
Autor:
Zizhuo TU, Yaozu XIANG
Publikováno v:
Journal of Holistic Integrative Pharmacy, Vol 3, Iss 1, Pp 18-23 (2022)
Cardiovascular disease (CVD) is the leading cause of death worldwide. It has been recognized that specific regulatory factors from peripheral tissues can influence the pathological progression of atherosclerosis, myocardial infarction (MI) and heart
Externí odkaz:
https://doaj.org/article/3101ad4ad4a94365a2e09b44ed41d551
Autor:
Xuyan Gong, Han Zhang, Xiaoqiao Xu, Yunpeng Ding, Xingbo Yang, Zhiyang Cheng, Dike Tao, Congjiao Hu, Yaozu Xiang, Yao Sun
Publikováno v:
International Journal of Oral Science, Vol 14, Iss 1, Pp 1-9 (2022)
Abstract Neural crest-derived mesenchymal stem cells (MSCs) are known to play an essential function during tooth and skeletal development. PRX1+ cells constitute an important MSC subtype that is implicated in osteogenesis. However, their potential fu
Externí odkaz:
https://doaj.org/article/1ee9e6c98d79454483944dd5dec42a2e
Autor:
Guodong Li, Chung-Nga Ko, Dan Li, Chao Yang, Wanhe Wang, Guan-Jun Yang, Carmelo Di Primo, Vincent Kam Wai Wong, Yaozu Xiang, Ligen Lin, Dik-Lung Ma, Chung-Hang Leung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Impaired wound healing is a serious complication in diabetic patients, and is associated with reduced HIF1α stability. Here, the authors design a small molecule that stabilizes HIF1α by blocking its interaction with VHL and show that it promotes wo
Externí odkaz:
https://doaj.org/article/ab01c58730bb45109483db19c65692d4
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3319-3329 (2021)
Mitochondria, as the energy factory of cells, participate in metabolism processes and play a critical role in the maintenance of human life activities. Mitochondria belong to semi-automatic organelles, which have their own genome different from nucle
Externí odkaz:
https://doaj.org/article/a1e78b404d814b48b31712774c3c6b7f
Autor:
Xiaowen Shao, Dandan Wang, Yue Xu, Ling Guo, Hui Yang, Jieru Zhou, Jiayi Liang, Jie Qian, Jiajing Cheng, Lihua Sun, Yaozu Xiang
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 1505-1511 (2021)
AbstractObjectives Early fetal demise (absence of cardiac activity in a visible fetus) is a very common event, but there are no reliable biomarkers to predict it. The purpose of the study was to assess the association of platelet parameters with earl
Externí odkaz:
https://doaj.org/article/50503316f8ee46ae85405d8518dd584d
Autor:
Wenqi Dong, Gaoyan Wang, Jiajia Feng, Pei Li, Rui Wang, Hao Lu, Wenjia Lu, Chenchen Wang, Xiangru Wang, Huanchun Chen, Yaozu Xiang, Chen Tan
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104279- (2022)
Summary: Mycobacterium tuberculosis (Mtb) evades host clearance by inhibiting autophagy. MicroRNA-25 (miR-25) expression was significantly up-regulated in the lung tissues of mice infected with Bacillus Calmette-Guerin (BCG) and macrophages infected
Externí odkaz:
https://doaj.org/article/f1ed3c90fb1c4a1f8de385448b6fc63a