Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Yaowen Gu"'
1
Akademický článek
Study on tumour cell-derived hybrid exosomes as dasatinib nanocarriers for pancreatic cancer therapy
Autor: Xiaofei Zhou, Yuetang Zhuang, Xiaohong Liu, Yaowen Gu, Junting Wang, Yuchen Shi, Li Zhang, Rui Li, Yelin Zhao, Hebing Chen, Jiao Li, Hongjuan Yao, Liang Li
Publikováno v: Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 532-546 (2023)
AbstractPancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death. Therefore, we intend to explore novel strategies against PDAC. The exosomes-based biomimetic nanoparticle is an appealing candidate served as a drug
Externí odkaz: https://doaj.org/article/398b986dd7c84ee08bf60d529f47ce86
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2
Akademický článek
Developing a Personalized Meal Recommendation System for Chinese Older Adults: Observational Cohort Study
Autor: Zidu Xu, Yaowen Gu, Xiaowei Xu, Maxim Topaz, Zhen Guo, Hongyu Kang, Lianglong Sun, Jiao Li
Publikováno v: JMIR Formative Research, Vol 8, p e52170 (2024)
BackgroundChina’s older population is facing serious health challenges, including malnutrition and multiple chronic conditions. There is a critical need for tailored food recommendation systems. Knowledge graph–based food recommendations offer co
Externí odkaz: https://doaj.org/article/03b2eb72a0fa434c8e23721ec4d4f3f1
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3
Akademický článek
Prediction of Medical Disputes Between Health Care Workers and Patients in Terms of Hospital Legal Construction Using Machine Learning Techniques: Externally Validated Cross-Sectional Study
Autor: Min Yi, Yuebin Cao, Lin Wang, Yaowen Gu, Xueqian Zheng, Jiangjun Wang, Wei Chen, Liangyu Wei, Yujin Zhou, Chenyi Shi, Yanlin Cao
Publikováno v: Journal of Medical Internet Research, Vol 25, p e46854 (2023)
BackgroundMedical disputes are a global public health issue that is receiving increasing attention. However, studies investigating the relationship between hospital legal construction and medical disputes are scarce. The development of a multicenter
Externí odkaz: https://doaj.org/article/50b4fc584670493d978111ff585556fe
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4
Akademický článek
Drug–disease association prediction with literature based multi-feature fusion
Autor: Hongyu Kang, Li Hou, Yaowen Gu, Xiao Lu, Jiao Li, Qin Li
Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Exploring the potential efficacy of a drug is a valid approach for drug development with shorter development times and lower costs. Recently, several computational drug repositioning methods have been introduced to learn multi-features
Externí odkaz: https://doaj.org/article/0536d371463b469f93369cb83f1f4b4e
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5
Akademický článek
Employing Molecular Conformations for Ligand-Based Virtual Screening with Equivariant Graph Neural Network and Deep Multiple Instance Learning
Autor: Yaowen Gu, Jiao Li, Hongyu Kang, Bowen Zhang, Si Zheng
Publikováno v: Molecules, Vol 28, Iss 16, p 5982 (2023)
Ligand-based virtual screening (LBVS) is a promising approach for rapid and low-cost screening of potentially bioactive molecules in the early stage of drug discovery. Compared with traditional similarity-based machine learning methods, deep learning
Externí odkaz: https://doaj.org/article/05a6da4172b04a1796e73e5df53eb3e6
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7
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction
Autor: Yaowen Gu, Si Zheng, Qijin Yin, Rui Jiang, Jiao Li
Publikováno v: Computers in biology and medicine. 150
Computational drug repositioning is an effective way to find new indications for existing drugs, thus can accelerate drug development and reduce experimental costs. Recently, various deep learning-based repurposing methods have been established to id
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce218ef3b2cd4ab46134dbd6cca0981d
https://pubmed.ncbi.nlm.nih.gov/36182762
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8
Developing a Siamese Network for UTIs Risk Prediction in Immobile Patients Undergoing Stroke
Autor: Zidu Xu, Chen Zhu, Yaowen Gu, Si Zheng, Xiangyu Sun, Jing Cao, Xinjuan Wu, Jiao Li
Stroke patients tend to suffer from immobility, which increases the possibility of post-stroke complications. Urinary tract infections (UTIs) are one of the complications as an independent predictor of poor prognosis of stroke patients. However, the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::170ee356f6a8eb8a1c348641a3f6fedf
https://doi.org/10.3233/shti220171
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10
An efficient curriculum learning-based strategy for molecular graph learning
Autor: Yaowen Gu, Si Zheng, Zidu Xu, Qijin Yin, Liang Li, Jiao Li
Publikováno v: Briefings in bioinformatics. 23(3)
Computational methods have been widely applied to resolve various core issues in drug discovery, such as molecular property prediction. In recent years, a data-driven computational method-deep learning had achieved a number of impressive successes in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c1001bf52a14ab7992fa1a933fda7b
https://pubmed.ncbi.nlm.nih.gov/35368074
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