Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yaolan Lin"'
Publikováno v:
Journal of Natural Products. 83:3230-3238
Eight new germacranolides, minusolides A–H (1–8), along with two known analogues, 9 and 10, were isolated from the whole plant of Carpesium minus. Their structures were elucidated by spectroscopic ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af0737ec5bb3ed85d5176f1941bb345
https://doi.org/10.1021/acs.jnatprod.0c00428
https://doi.org/10.1021/acs.jnatprod.0c00428
Autor:
Li Zhu, Xiao-Qin Liu, Wen-Li Wang, Ling-Nan Li, Jian-Guang Luo, Chen Chen, Ling-Yi Kong, Yaolan Lin, Dong-Rong Zhu
Publikováno v:
Organic Chemistry Frontiers. 6:3369-3373
A pair of novel C23 terpenoid epimers, officinalins A (1) and B (2), together with a biogenetically related known diterpenoid (3), was isolated from the leaves of Salvia officinalis. The epimers feature an unprecedented carbon skeleton with a tetracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b8463519b2fad92453a0d373d0a068
https://doi.org/10.1039/c9qo00861f
https://doi.org/10.1039/c9qo00861f
Autor:
Xiao-Qin Liu, Yaolan Lin, Chao Han, Ling-Nan Li, Wen-Li Wang, Li Zhu, Jian-Guang Luo, Ling-Yi Kong
Publikováno v:
Journal of chromatography. A. 1625
It is significant to precisely isolate potential active compounds from medicinal herbs containing multiple compounds. Herein, a new strategy for precise separation of lysine-specific demethylase 1 (LSD1) inhibitors from the rhizome of Corydalis yanhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a547ad1ba9e9c599a76940696777fa7a
https://pubmed.ncbi.nlm.nih.gov/32709337
https://pubmed.ncbi.nlm.nih.gov/32709337
Publikováno v:
Journal of Chromatography A. 1575:122-127
Synephrine, a chiral adrenergic agonist, exists as R- (more active) and S-enantiomers (less active) that are difficult to separate because of their alkalinity and high polarity. Herein, we show that although this enantioseparation can hardly be achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45634069fef0275ac3b7c70d3430333
https://doi.org/10.1016/j.chroma.2018.09.012
https://doi.org/10.1016/j.chroma.2018.09.012
Publikováno v:
Bioorganic chemistry. 96
Six new obovatol trimeric neolignans, houpulignans A–F (1–6) were isolated from the leaves of Magnolia officinalis var. biloba. Their structures were determined on the basis of the interpretation of HRESIMS, NMR data, and electronic circular dich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e00fddd2a5558975dd326d503e7ab6
https://pubmed.ncbi.nlm.nih.gov/31982819
https://pubmed.ncbi.nlm.nih.gov/31982819
Publikováno v:
Analytica chimica acta. 1099
In terms of ligand fishing, the amount and the relative activity recovery of enzymes immobilized on magnetic particles and nanoparticles are not preeminent. Therefore, the metal-organic framework (MOF) UiO-66-NH2 was synthesized to immobilize the por
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8c57e7bd96e7372c07716c2b0f4ba0
https://pubmed.ncbi.nlm.nih.gov/31986282
https://pubmed.ncbi.nlm.nih.gov/31986282
Autor:
Wen-Li Wang, Yaolan Lin, Qi-Qi Xu, Dong-Rong Zhu, Ling-Yi Kong, Chao Han, Ling-Nan Li, Jian-Guang Luo
Publikováno v:
Talanta. 206
The ability to separate bioactive compounds from herbal medicines, which contain abundant components, is crucial for drug discovery. Conventional Countercurrent chromatography (CCC) methods for separating bioactive compounds are labor intensive and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c165bf14329941b79a215de5cf5e34
https://pubmed.ncbi.nlm.nih.gov/31514831
https://pubmed.ncbi.nlm.nih.gov/31514831
Autor:
Chao Han, Chunling Ren, Xiao Xu, Xiao-Qin Liu, Dan Yan, Ling-Yi Kong, Yaolan Lin, Dong-Rong Zhu
Publikováno v:
Bioorganic Chemistry. 108:104666
Lysine-specific histone demethylase 1 (LSD1) was the first histone demethylase identified in epigenetics and has recently emerged as an attractive therapeutic target for treating tumors. To date, almost all reported LSD1 inhibitors have been chemosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd0a7cc343fcbabfb5ae3203be05a88
https://doi.org/10.1016/j.bioorg.2021.104666
https://doi.org/10.1016/j.bioorg.2021.104666
Autor:
Ying Li, Chen Chen, Wu-Xi Zhou, Xiu-Tao Wu, Jian-Guang Luo, Yaolan Lin, Xiao-Qin Liu, Ling-Yi Kong
Publikováno v:
European Journal of Medicinal Chemistry. 210:112980
To develop novel GLS1 inhibitors as effective therapeutic agents for triple-negative breast cancer (TNBC), 25 derivatives were synthesized from the natural inhibitor withangulatin A (IC50 = 18.2 μM). Bioassay optimization identified a novel and sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1268f05204259b6401884c0c855765
https://doi.org/10.1016/j.ejmech.2020.112980
https://doi.org/10.1016/j.ejmech.2020.112980
Publikováno v:
Tetrahedron Letters. 61:151385
Hyperpatulones A (1) and B (2), two new polycyclic polyprenylated acylphloroglucinols (PPAPs), were isolated from the leaves of Hypericum patulum. Their unusual 6,7,5-tricyclic system with a peroxide bridge structures were elucidated by comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a211c91c5c1bdf05dd57311cd9e02613
https://doi.org/10.1016/j.tetlet.2019.151385
https://doi.org/10.1016/j.tetlet.2019.151385