Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yaolan Li"'
Autor:
Lifeng Chen, Jingjing Zhang, Weibin Xu, Jiayi Chen, Yujun Tang, Si Xiong, Yaolan Li, Hong Zhang, Manmei Li, Zhong Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Respiratory syncytial virus (RSV) hijacks cholesterol or autophagy pathways to facilitate optimal replication. However, our understanding of the associated molecular mechanisms remains limited. Here, we show that RSV infection blocks cholest
Externí odkaz:
https://doaj.org/article/f9c55b0bc24d44789ac2675caecff681
Autor:
Qiaoyun Song, Haoyue Zhu, Manlan Qiu, Jialiao Cai, Yun Hu, Haixia Yang, Shuwen Rao, Yaolan Li, Manmei Li, Lijun Hu, Shuqin Wang, Jian Hong, Wencai Ye, Heru Chen, Ying Wang, Wei Tang
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Infection with respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract disease in young children and older people. Despite intensive efforts over the past few decades, no direct-acting small-molecule agents agains
Externí odkaz:
https://doaj.org/article/6a579b034b354320b9636abfc352a731
Autor:
Jun He, Huibin Huang, Bo Li, Huanan Li, Yue Zhao, Yaolan Li, Wencai Ye, Wenbao Qi, Wei Tang, Lei Wang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Human infection with highly pathogenic H5N1 influenza virus causes severe respiratory diseases. Currently, the drugs against H5N1 are limited to virus-targeted inhibitors. However, drug resistance caused by these inhibitors is becoming a serious thre
Externí odkaz:
https://doaj.org/article/a8d7ce622efd4a1dbd8ca13dd42b2ff4
Autor:
Shaomin Yang, Xiaolian Liu, Mei Wang, Di Cao, Dabbu Kumar Jaijyan, Nicole Enescu, Jian Liu, Songbin Wu, Sashuang Wang, Wuping Sun, Lizu Xiao, Alison Gu, Yaolan Li, Hong Zhou, Sanjay Tyagi, Jianguo Wu, Qiyi Tang, Hua Zhu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Human cytomegalovirus (HCMV) infects a large portion of the human population globally. Several HCMV-derived noncoding RNAs are involved in the regulation of viral gene expression and the virus life cycle. Here, we reported that circRNAs are
Externí odkaz:
https://doaj.org/article/7e0bdef9ffba4424ae73d7c6ad87e447
Autor:
Ding Luo, Zhenchao Tu, Wenjing Yin, Chunlin Fan, Nenghua Chen, Zhongnan Wu, Weilong Ding, Yaolan Li, Guocai Wang, Yubo Zhang
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Four new alkaloids (1–4) belonging to rare examples of bis-amide matrine-type were isolated from the seeds of sophora alopecuroides. Their structures including absolute configuration were determined by extensive spectroscopic analysis, electronic c
Externí odkaz:
https://doaj.org/article/bbee8676971341ccbb061399f513f8ab
Autor:
Canjie Li, Xin Sun, Wenjing Yin, Zhaochun Zhan, Qing Tang, Wenzhi Wang, Xuefang Zhuo, Zhongnan Wu, Haipeng Zhang, Yaolan Li, Yubo Zhang, Guocai Wang
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Seven new clerodane diterpenoids, crassifolins Q−W (1–7), along with five known analogues (8–12), were isolated from the roots of Croton crassifolius. Their structures were identified by comprehensive spectroscopic analysis (UV, IR, NMR, and HR
Externí odkaz:
https://doaj.org/article/bd458014710c458e897ff67b4ea70899
Publikováno v:
Viruses, Vol 11, Iss 9, p 835 (2019)
With the emergence of drug-resistant strains of influenza A viruses (IAV), new antivirals are needed to supplement the existing counter measures against IAV infection. We have previously shown that brevilin A, a sesquiterpene lactone isolated from C.
Externí odkaz:
https://doaj.org/article/1713d94680f64c91a5c16916ddeb72b0
Publikováno v:
Molecules, Vol 14, Iss 6, Pp 2135-2146 (2009)
Centipeda minima is a medicinal plant reputed in China as a remedy for nasopharyngeal carcinoma (NPC). In this study, bioactivity-guided fractionation of the anti-NPC compound(s) from C. minima led to the isolation of 2β-(isobutyryloxy)florilenalin
Externí odkaz:
https://doaj.org/article/a53af77e8afc48318f88c658d8e84046
Publikováno v:
Molecules, Vol 22, Iss 1, p 126 (2017)
Anti-angiogenesis targeting vascular endothelial growth factor receptor-2 (VEGFR-2) has been considered as an important strategy for cancer therapy. Penduliflaworosin is a diterpenoid isolated from the plant Croton crassifolius. Our previous study sh
Externí odkaz:
https://doaj.org/article/0cfb1d9f5d834a60bf74d7656a68ee2d
Autor:
Zhongnan Wu, Xiaoyong Dai, Wenzhi Wang, Xianfang Zhang, Jiawei Chen, Jing Liu, Laiqiang Huang, Yaolan Li, Shuixing Zhang, Guocai Wang, Yubo Zhang
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:10506-10520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b07d101d2ce11b746cc04c22ea926d1
https://doi.org/10.1021/acs.jafc.2c04216
https://doi.org/10.1021/acs.jafc.2c04216