Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yaojiong WU"'
Autor:
Ruiqing Lu, Ke Zheng, Yongjie Zhou, Weibu Wang, Yanan Zhang, Yu Chen, Miaohua Mo, Xiaosong Li, Yankai Dong, Jundong Xie, Haiji Zhang, Qingyang Yang, Guoliang Wang, Yi Zhao, Yaojiong Wu
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110811- (2024)
Summary: Mesenchymal stem cells (MSCs) are heterogeneous in morphology and transcriptome, resulting in varying therapeutic outcomes. In this study, we found that 3D spheroid culture of heterogeneous MSCs, which have undergone conventional 2D monolaye
Externí odkaz:
https://doaj.org/article/0daa3ae51b5c442294d5f9942c9f1bcf
Autor:
Chunyan Feng, Albert Yu, Zhongfu Wang, Kun Wang, Jiawei Chen, Yaojiong Wu, Ting Deng, Huaqing Chen, Yibo Hou, Shaohua Ma, Xiaoyong Dai, Laiqiang Huang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-24 (2024)
Abstract Background Podoplanin (PDPN) is a highly conserved, mucin-type protein specific to the lymphatic system. Overexpression of PDPN is associated with the progression of various solid tumors, and plays an important roles in the tumor microenviro
Externí odkaz:
https://doaj.org/article/cbd72382ce834b898e743362e21b53b9
Autor:
Guang Yang, Haiyan Chen, Qun Chen, Jiayi Qiu, Mulan Qahar, Zhimeng Fan, Weiwei Chu, Edward E. Tredget, Yaojiong Wu
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-18 (2023)
Abstract Background The hair follicles (HFs) are barely regenerated after loss in injuries in mammals as well as in human beings. Recent studies have shown that the regenerative ability of HFs is age-related; however, the relationship between this ph
Externí odkaz:
https://doaj.org/article/7556e82bc33d4ba9a9e34b61d6f1f13d
Autor:
Yuanxiong Cao, Jiayi Tan, Haoran Zhao, Ting Deng, Yunxia Hu, Junhong Zeng, Jiawei Li, Yifan Cheng, Jiyuan Tang, Zhiwei Hu, Keer Hu, Bing Xu, Zitian Wang, Yaojiong Wu, Peter E. Lobie, Shaohua Ma
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Current mesenchymal stem cell (MSC) transplantation practices are limited by the loss or reduced performance of MSCs. Here the authors develop a bead-jet printer for intraoperative formulation and printing of MSCs-laden Matrigel beads to improve skel
Externí odkaz:
https://doaj.org/article/0a68d6a2529540a2ac2e944d9137b981
Autor:
Ye Ran, Yankai Dong, Yuejiao Li, Jundong Xie, Shubin Zeng, Chuanlei Liang, Wei Dai, Wenjing Tang, Yaojiong Wu, Shengyuan Yu
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Mesenchymal stem cells (MSCs) have shown immense therapeutic potential for various brain diseases. Intrathecal administration of MSCs may enhance their recruitment to lesions in the central nervous system, but any impact on cerebr
Externí odkaz:
https://doaj.org/article/7432eb85e51c4b699994460b5a1b28d5
Distinct bulge stem cell populations maintain the pilosebaceous unit in a β-catenin-dependent manner
Autor:
Jimin Han, Kaijun Lin, HuiQin Choo, Yu Chen, Xuezheng Zhang, Ren-He Xu, Xusheng Wang, Yaojiong Wu
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105805- (2023)
Summary: The pilosebaceous unit (PSU) is composed of multiple compartments and the self-renewal of PSU depends on distinct hair follicle stem cell (HFSC) populations. However, the differential roles of the HFSCs in sebaceous gland (SG) renewal have n
Externí odkaz:
https://doaj.org/article/72bcd1dfb7184b8999f56438588616c5
Autor:
Yuejiao Li, Yankai Dong, Ye Ran, Yanan Zhang, Boyao Wu, Jundong Xie, Yanpei Cao, Miaohua Mo, Sen Li, Hao Deng, Wenbo Hao, Shengyuan Yu, Yaojiong Wu
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background We show previously that three-dimensional (3D) spheroid cultured mesenchymal stem cells (MSCs) exhibit reduced cell size thus devoid of lung entrapment following intravenous (IV) infusion. In this study, we determined the therapeu
Externí odkaz:
https://doaj.org/article/55a3d404d76949ba85beea52c4d55a05
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Rationale: β-catenin signaling controls multiple fibroblast subsets, with its overactivity promoting the differentiation of hair follicle dermal stem cells (hfDSCs) and the hyperactivation of interfollicular fibroblasts. Understanding the concept of
Externí odkaz:
https://doaj.org/article/feb4ade19bb0452e88a071b12654da69
Autor:
Xi Chen, Xingyu Liu, Yiou Wang, Ruichen Ma, Shibai Zhu, Shanni Li, Songlin Li, Xiying Dong, Hairui Li, Guangzhi Wang, Yaojiong Wu, Yiling Zhang, Guixing Qiu, Wenwei Qian
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundAccurate preoperative planning is essential for successful total hip arthroplasty (THA). However, the requirements of time, manpower, and complex workflow for accurate planning have limited its application. This study aims to develop a comp
Externí odkaz:
https://doaj.org/article/0a97be8a7cdc480cb58de8c8bd117f55
Autor:
Yu Chen, Zhimeng Fan, Xiaoxiao Wang, Miaohua Mo, Shu Bin Zeng, Ren-He Xu, Xusheng Wang, Yaojiong Wu
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background Cultured epidermal stem cells (Epi-SCs) and skin-derived precursors (SKPs) were capable of reconstituting functional hair follicles after implantation, while the signaling pathways that regulate neogenic hair follicle formation ar
Externí odkaz:
https://doaj.org/article/d80c1faedbd247419aabd642043a5b38