Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yao-Yao Yan"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractIt has been reported that CDK8 plays a key role in acute myeloid leukaemia. Here, a total of 40 compounds were rational designed and synthesised based on the previous SAR. Among them, compound 12 (3-(3-(furan-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-
Externí odkaz:
https://doaj.org/article/c640f4ab38284665aee61e6a6e5813b7
Autor:
Yao Yao, Yan, Xing Xing, Zhang, Yun, Xiao, Xiao Bao, Shen, Yu Jie, Jian, Yu Meng, Wang, Zi Hao, She, Ming Ming, Liu, Xin Hua, Liu
Publikováno v:
Journal of Medicinal Chemistry. 65:13216-13239
CDK8 is a transcriptional cyclin-dependent kinase and considered as a potential target in colon cancer therapeutics. Here, a novel selective CDK8 inhibitor was identified against colon cancer
Autor:
Xing Xing Zhang, Yun Xiao, Yao Yao Yan, Yu Meng Wang, Han Jiang, Lei Wu, Jing-bo Shi, Xin Hua Liu
Publikováno v:
Journal of Medicinal Chemistry. 65:12095-12123
Autor:
Xing Xing Zhang, Yao Yao Yan, Xiao Ma, Yun Xiao, Cen Cen Lei, Yu Meng Wang, Chao Liu, Quan Wang, Xing Tao Zhang, Wen Dan Cheng, Xin Hua Liu
Publikováno v:
European Journal of Medicinal Chemistry. 251:115214
Autor:
Xi-Shuang Liu, Shi-Chao Xing, Dong-Mei Meng, Changgui Li, Na Li, Jiang Gang, Yao-Yao Yan, Ying Chen
Publikováno v:
Cell biochemistry and biophysics. 71(2)
To analyze the diversity of both Bacteroides and Clostridium in patients with primary gout and the difference from that of normal individuals. And to investigate the relationship between the primary gout and the intestinal flora. Fecal samples of 90