Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Yao-Cheng Li"'
Autor:
Rui Tang, Emily G. Shuldiner, Marcus Kelly, Christopher W. Murray, Jess D. Hebert, Laura Andrejka, Min K. Tsai, Nicholas W. Hughes, Mitchell I. Parker, Hongchen Cai, Yao-Cheng Li, Geoffrey M. Wahl, Roland L. Dunbrack, Peter K. Jackson, Dmitri A. Petrov, Monte M. Winslow
Publikováno v:
Nature Cell Biology. 25:159-169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d57cd5248d3f14dde94a8638efa11d0
https://doi.org/10.1038/s41556-022-01049-w
https://doi.org/10.1038/s41556-022-01049-w
Autor:
Margie N. Sutton, Zhen Lu, Yao-Cheng Li, Yong Zhou, Tao Huang, Albert S. Reger, Amy M. Hurwitz, Timothy Palzkill, Craig Logsdon, Xiaowen Liang, Joe W. Gray, Xiaolin Nan, John Hancock, Geoffrey M. Wahl, Robert C. Bast, Jr.
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3448-3459.e6 (2019)
Summary: Oncogenic RAS mutations drive cancers at many sites. Recent reports suggest that RAS dimerization, multimerization, and clustering correlate strongly with activation of RAS signaling. We have found that re-expression of DIRAS3, a RAS-related
Externí odkaz:
https://doaj.org/article/732fd049e7a34e8a9980c8c274457ff8
Animals have evolved two defense strategies to survive infections. Antagonistic strategies include mechanisms of immune resistance that operate to sense and kill invading pathogens. Cooperative or physiological defenses mediate host adaptation to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c1912fbd5ff59f684cb66473b8aa67
https://doi.org/10.1101/2023.01.22.525099
https://doi.org/10.1101/2023.01.22.525099
Autor:
Yao-Cheng Li, Luo Wei Rodewald, Christian Hoppmann, Ee Tsin Wong, Sylvain Lebreton, Pavel Safar, Marcel Patek, Lei Wang, Kenneth F. Wertman, Geoffrey M. Wahl
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1946-1958 (2014)
Summary: Protein-protein interactions (PPIs) play central roles in orchestrating biological processes. While some PPIs are stable, many important ones are transient and hard to detect with conventional approaches. We developed ReBiL, a recombinase en
Externí odkaz:
https://doaj.org/article/5a4bc3afe47e4b059d3a69fe8d2115f6
Autor:
Christopher J. Murray, Geoffrey M. Wahl, Min Tsai, Laura Andrejka, Nicholas W. Hughes, Emily G. Shuldiner, Mitchell I. Parker, Peter K. Jackson, Hongchen Cai, Dmitri A. Petrov, Rui Tang, Jess D. Hebert, Monte M. Winslow, Roland L. Dunbrack, Yao-Cheng Li, Marcus R. Kelly
Oncogenic KRAS mutations occur in approximately 30% of lung adenocarcinoma. Despite several decades of effort, oncogenic KRAS-driven lung cancer remains difficult to treat, and our understanding of the positive and negative regulators of RAS signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbc6c30416a3613412072052f10cf80
https://doi.org/10.21203/rs.3.rs-900548/v1
https://doi.org/10.21203/rs.3.rs-900548/v1
Autor:
Jennifer L Green, Matthieu Bauer, Kyu Won Yum, Yao-Cheng Li, Miranda L Cox, Karl Willert, Geoffrey M Wahl
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58395 (2013)
Functional and mechanistic studies of Wnt signaling have been severely hindered by the inaccessibility of bioactive proteins. To overcome this long-standing barrier, we engineered and characterized a panel of Chinese hamster ovary (CHO) cell lines wi
Externí odkaz:
https://doaj.org/article/aac915aceeeb4a5aa7104de4b315754a
Autor:
Robert C. Bast, Channing J. Der, Frank McCormick, David Piwnica-Worms, Yao-Cheng Li, Margie N. Sutton, Geoffrey M. Wahl, Luke Wang, Tikvah K. Hayes, Nikki K. Lytle, Seth T. Gammon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 22
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
HRAS, NRAS, and KRAS4A/KRAS4B comprise the RAS family of small GTPases that regulate signaling pathways controlling cell proliferation, differentiation, and survival. RAS pathway abnormalities cause developmental disorders and cancers. We found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69fe92e6ac8ce52b358a84727adaacc
https://escholarship.org/uc/item/7mn5f7xv
https://escholarship.org/uc/item/7mn5f7xv
Autor:
Yao-Cheng Li, Lytle, Nikki K., Gammon, Seth T., Luke Wang, Hayes, Tikvah K., Sutton, Margie N., Bast Jr., Robert C., Der, Channing J., Piwnica-Worms, David, McCormick, Frank, Wahl, Geoffrey M.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/2/2020, Vol. 117 Issue 22, p1-10, 10p
Autor:
Kodye Abbott, Edward C. Stites, Yao-Cheng Li, Thomas McFall, Jianfeng Huang, Geoffrey M. Wahl, Jingting Yu, Gaurav Mendiratta, Maxim N. Shokhirev
RAF kinase inhibitors can, in some conditions, increase RAF kinase signaling. This process, which is commonly referred to as “paradoxical activation” (PA), is incompletely understood. RAF kinases are regulated by autoinhibitory conformational cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599523365eb6359533b6bb0487f5ca10
https://doi.org/10.1101/849489
https://doi.org/10.1101/849489
Autor:
Yao-Cheng Li, Tzu-Hao Cheng
Publikováno v:
Science. 1/26/2001, Vol. 291 Issue 5504, p650-653. 4p. 5 Diagrams, 2 Graphs.