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Multi-target anti-MRSA mechanism and antibiotic synergistic effect of marine alkaloid Ascomylactam A in vitro and in vivo against clinical MRSA strains.

Autor: Wu KY; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China; University of Chinese Academy of Sciences, Beijing 100049, China., Yao FH; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China., Ren XM; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China; University of Chinese Academy of Sciences, Beijing 100049, China., Hang XD; Department of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, China., Bai YF; Department of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, China., Qi SH; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China. Electronic address: shuhuaqi@scsio.ac.cn.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Dec 04; Vol. 232, pp. 116697. Date of Electronic Publication: 2024 Dec 04.

Microascones, Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus Microascus sp. SCSIO 41821.

Autor: Yao FH; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Liang X; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China.; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China., Shen WB; New Drug Research & Development Center of North China Pharmaceutical Group Corporation, National Engineering Research Center of Microbial Medicine, Hebei industry Microbial Metabolic Technology Innovation Centre, Shijiazhuang Microbial Drugs Technology Innovation Center, Hebei Synthetic Biology High-Energy-Level Technology Innovation Center, Shijiazhuang 050015, Hebei, China., Lu XH; New Drug Research & Development Center of North China Pharmaceutical Group Corporation, National Engineering Research Center of Microbial Medicine, Hebei industry Microbial Metabolic Technology Innovation Centre, Shijiazhuang Microbial Drugs Technology Innovation Center, Hebei Synthetic Biology High-Energy-Level Technology Innovation Center, Shijiazhuang 050015, Hebei, China., Li GC; New Drug Research & Development Center of North China Pharmaceutical Group Corporation, National Engineering Research Center of Microbial Medicine, Hebei industry Microbial Metabolic Technology Innovation Centre, Shijiazhuang Microbial Drugs Technology Innovation Center, Hebei Synthetic Biology High-Energy-Level Technology Innovation Center, Shijiazhuang 050015, Hebei, China., Qi SH; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, Guangdong, China.; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China.

Publikováno v: Journal of natural products [J Nat Prod] 2024 Apr 26; Vol. 87 (4), pp. 810-819. Date of Electronic Publication: 2024 Mar 01.

Design, synthesis, and biological evaluation of dinuclear bismuth(III) complexes with Isoniazid-derived Schiff bases.

Autor: Li CH; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China. Electronic address: lichuanhua@xnu.edu.cn., Jiang JH; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Lei YH; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China. Electronic address: leiyh_1823@xnu.edu.cn., Li X; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Yao FH; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Ji MH; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Zhang KW; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Tao LM; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Ye LJ; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China., Li QG; Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, Hunan Province, China.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2022 Oct; Vol. 235, pp. 111931. Date of Electronic Publication: 2022 Jul 16.