Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yao E Wang"'
Autor:
Preeti Bharaj, Yao E Wang, Brian E Dawes, Tatyana E Yun, Arnold Park, Benjamin Yen, Christopher F Basler, Alexander N Freiberg, Benhur Lee, Ricardo Rajsbaum
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005880 (2016)
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system. Nipah virus (NiV), a highly pathogenic member of the Paramyxoviridae family (genus Henipavirus),
Externí odkaz:
https://doaj.org/article/ba0da777b7ea4d80b4ea6b3307a3d2e3
Autor:
Mickey Pentecost, Ajay A Vashisht, Talia Lester, Tim Voros, Shannon M Beaty, Arnold Park, Yao E Wang, Tatyana E Yun, Alexander N Freiberg, James A Wohlschlegel, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004739 (2015)
The paramyxovirus matrix (M) protein is a molecular scaffold required for viral morphogenesis and budding at the plasma membrane. Transient nuclear residence of some M proteins hints at non-structural roles. However, little is known regarding the mec
Externí odkaz:
https://doaj.org/article/e0e16e96e7c14b2eb3f3d427fa4a45e5
Autor:
Yao E Wang, Arnold Park, Michael Lake, Mickey Pentecost, Betsabe Torres, Tatyana E Yun, Mike C Wolf, Michael R Holbrook, Alexander N Freiberg, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001186 (2010)
Paramyxoviruses are known to replicate in the cytoplasm and bud from the plasma membrane. Matrix is the major structural protein in paramyxoviruses that mediates viral assembly and budding. Curiously, the matrix proteins of a few paramyxoviruses have
Externí odkaz:
https://doaj.org/article/6b21b19e495a41a9bde4c6acd5afe674
Autor:
Jingfeng Wang, Yao E. Wang, Su-Yang Liu, Chunfeng Li, Hsiang-Wen Chen, Taijiao Jiang, F. Xiao-Feng Qin, Ping Liu, Genhong Cheng, Natalie Quanquin, Aiping Wu, Lulan Wang, Hong Zhang
Publikováno v:
Journal of virology, vol 90, iss 6
Influenza virus mRNA synthesis by the RNA-dependent RNA polymerase involves binding and cleavage of capped cellular mRNA by the PB2 and PA subunits, respectively, and extension of viral mRNA by PB1. However, the mechanism for such a dynamic process i
Autor:
Terence E. Hill, Shannon M. Beaty, Tatyana Yun, Yao E. Wang, Benhur Lee, Frederic Vigant, Junling Gao, Lihong Zhang, Arnold Park, Terry L. Juelich, Alexander N. Freiberg, Olivier Pernet, Ping Wu, Jennifer K. Smith
Publikováno v:
Journal of Virology. 89:1242-1253
Nipah virus (NiV) and Hendra virus (HeV) are closely related henipaviruses of the Paramyxovirinae . Spillover from their fruit bat reservoirs can cause severe disease in humans and livestock. Despite their high sequence similarity, NiV and HeV exhibi
Autor:
Yingfang Liu, Genhong Cheng, Feng Feng, Yao E Wang, Lingmin Yuan, Su Zeng, Huanhuan Liang, Christopher S. Crowley, Jingjing Li, Zongyang Lv
Publikováno v:
Cell Research. 23:1055-1058
Autor:
Halmurat Upur, Zhi-Jie Liu, Genhong Cheng, Wei Ding, Yao E. Wang, Ping Zhu, Lianying Jiao, Fengfeng Niu, Neil Shaw, Songying Ouyang, Xiaomin Li
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9054-9059
Negative-stranded RNA viruses cover their genome with nucleoprotein (N) to protect it from the human innate immune system. Abrogation of the function of N offers a unique opportunity to combat the spread of the viruses. Here, we describe a unique fol
Autor:
Guiqin Wang, Paul Zhou, Tao Zhang, Barry R. Bloom, Xiaoli Tian, Robert L. Modlin, F. Xiao Feng Qin, Xu Juan, Yuying Liang, Zhanlong He, Maxime Chapon, Yao E. Wang, David Jesse Sanchez, Su-Yang Liu, Longding Liu, Genhong Cheng, Lulan Wang, Fan Zhou, Wenhai Yu, Jane C. Deng, Natalie Quanquin, Hsiang Wen Chen, Qihan Li, Taijiao Jiang
Publikováno v:
Cell host & microbe, vol 21, iss 3
Wang, Lulan; Liu, Su-Yang; Chen, Hsiang-Wen; Xu, Juan; Chapon, Maxime; Zhang, Tao; et al.(2017). Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets.. Cell host & microbe, 21(3), 334-343. doi: 10.1016/j.chom.2017.02.007. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2w18b918
Wang, Lulan; Liu, Su-Yang; Chen, Hsiang-Wen; Xu, Juan; Chapon, Maxime; Zhang, Tao; et al.(2017). Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets.. Cell host & microbe, 21(3), 334-343. doi: 10.1016/j.chom.2017.02.007. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2w18b918
New influenza vaccines that provide effective and broad protection are desperately needed. Live attenuated viruses are attractive vaccine candidates because they can elicit both humoral and cellular immune responses. However, recent formulations of l
Autor:
Tatyana Yun, Arnold Park, Ricardo Rajsbaum, Benhur Lee, Preeti Bharaj, Brian E. Dawes, Alexander N. Freiberg, Christopher F. Basler, Benjamin Yen, Yao E. Wang
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 9, p e1005880 (2016)
PLoS Pathogens, Vol 12, Iss 9, p e1005880 (2016)
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system. Nipah virus (NiV), a highly pathogenic member of the Paramyxoviridae family (genus Henipavirus),
Publikováno v:
Biology of the Cell
Nucleocytoplasmic trafficking of many cellular proteins is regulated by nuclear import/export signals as well as post-translational modifications such as covalent conjugation of ubiquitin and small ubiquitin-related modifiers (SUMOs). Ubiquitination