Zobrazeno 1 - 10 of 373 pro vyhledávání: '"Yao, Si"'
1
Akademický článek
Single cell analysis reveals the roles and regulatory mechanisms of type-I interferons in Parkinson’s disease
Autor: Pusheng Quan, Xueying Li, Yao Si, Linlin Sun, Fei Fan Ding, Yuwei Fan, Han Liu, Chengqun Wei, Ruihua Li, Xue Zhao, Fan Yang, Lifen Yao
Publikováno v: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract The pathogenesis of Parkinson’s disease (PD) is strongly associated with neuroinflammation, and type I interferons (IFN-I) play a crucial role in regulating immune and inflammatory responses. However, the specific features of IFN in differ
Externí odkaz: https://doaj.org/article/2d63cc2e150a4904a85ffec48e386de5
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2
Akademický článek
Mangiferin ameliorates polycystic ovary syndrome in rats by modulating insulin resistance, gut microbiota, and ovarian cell apoptosis
Autor: Zhang Yong, Chen Mimi, Li Yingjie, Guo Yichen, Yu Yansu, Zhou Zhi, Lu Hui, Yao Si, Wu Chongming, Zhang Xiaopo, Ma Ning, Lu Weiying
Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder characterized by hyperandrogenism, prolonged anovulation and polycystic ovaries. However, there are no effective interventions to treat this disorder. As previously shown,
Externí odkaz: https://doaj.org/article/f42896e85af446f79bbf572a535dca45
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4
Akademický článek
The microRNA-211-5p/P2RX7/ERK/GPX4 axis regulates epilepsy-associated neuronal ferroptosis and oxidative stress
Autor: Xueying Li, Pusheng Quan, Yao Si, Fei Liu, Yuwei Fan, Feifan Ding, Lina Sun, Han Liu, Shuo Huang, Linlin Sun, Fan Yang, Lifen Yao
Publikováno v: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Ferroptosis is an iron-dependent cell death mechanism involving the accumulation of lipid peroxides. As a critical regulator, glutathione peroxidase 4 (GPX4) has been demonstrated to be downregulated in epilepsy. However, the mechanism of fe
Externí odkaz: https://doaj.org/article/2953c029bf244ce0a230e142c21a2716
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