Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Yanzhi Song"'
Autor:
Shiyu Zuo, Chuo Li, Xiaolei Sun, Biping Deng, Yibing Zhang, Yajing Han, Zhuojun Ling, Jinlong Xu, Jiajia Duan, Zelin Wang, Xinjian Yu, Qinlong Zheng, Xiuwen Xu, Jiao Zong, Zhenglong Tian, Lingling Shan, Kaiting Tang, Huifang Huang, Yanzhi Song, Qing Niu, Dongming Zhou, Sizhou Feng, Zhongchao Han, Guoling Wang, Tong Wu, Jing Pan, Xiaoming Feng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Chimeric antigen receptor (CAR) T cells show suboptimal efficacy in acute myeloid leukemia (AML). We find that CAR T cells exposed to myeloid leukemia show impaired activation and cytolytic function, accompanied by impaired antigen receptor
Externí odkaz:
https://doaj.org/article/44e53ade52754034b066beff90fa2b1b
Autor:
Zhihui Li, Lei Wang, Qinlong Zheng, Teng Xu, Keyan Yang, Xianxuan Wang, Xiaopei Wen, Caiyan Zhang, Jingjing Wang, Yanzhi Song, Yongqiang Zhao, Xiaoyu Zheng, Tong Wu
Publikováno v:
Cancer Reports, Vol 7, Iss 6, Pp n/a-n/a (2024)
Abstract Background In December 2022, a large‐scale epidemic occurred in China due to Omicron variant of SARS‐CoV‐2. This study explored risk factors for Omicron infection in transplant recipients at our institution and investigated the factors
Externí odkaz:
https://doaj.org/article/194abea39ddc4d65b5c91b75a94292bf
Autor:
Xueying Tang, Jiashuo Zhang, Dezhi Sui, Zihan Xu, Qiongfen Yang, Tianyu Wang, Xiaoya Li, Xinrong Liu, Yihui Deng, Yanzhi Song
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100988- (2024)
The Pegylated lipids in lipid nanoparticle (LNPs) vaccines have been found to cause acute hypersensitivity reactions in recipients, and generate anti-LNPs immunity after repeated administration, thereby reducing vaccine effectiveness. To overcome the
Externí odkaz:
https://doaj.org/article/8f0b3acc1ca24533802b1fb76504328c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPatients with relapsed/refractory (r/r) acute T-lymphoblastic leukemia (T-ALL) have a poor prognosis. We developed donor CD7 chimeric antigen receptor T (CAR-T) cells to salvage r/r T-ALL patients and obtained encouraging results. Patient
Externí odkaz:
https://doaj.org/article/e32a49f9fad9417586a7488977549dea
Publikováno v:
PeerJ Computer Science, Vol 9, p e1480 (2023)
Training deep neural networks requires a large number of labeled samples, which are typically provided by crowdsourced workers or professionals at a high cost. To obtain qualified labels, samples need to be relabeled for inspection to control the qua
Externí odkaz:
https://doaj.org/article/e87dfffc9f6944fd8e710ea49ed4422c
Autor:
Dezhi Sui, Changzhi Li, Xueying Tang, Xianmin Meng, Junqiang Ding, Qiongfen Yang, Zhaowei Qi, Xinrong Liu, Yihui Deng, Yanzhi Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 425-439 (2023)
Immunoscenescence plays a key role in the initiation and development of tumors. Furthermore, immunoscenescence also impacts drug delivery and cancer therapeutic efficacy. To reduce the impact of immunosenescence on anti-tumor therapy, this experiment
Externí odkaz:
https://doaj.org/article/9cd1bb234ebe40f0a8eaf923e64eb367
Autor:
Meng Chen, Zhaowei Qi, Xianmin Meng, Shuo Wang, Xueying Zheng, Miao Hu, Xinrong Liu, Yanzhi Song, Yihui Deng
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 2, Pp 100784- (2023)
Checkpoint inhibitors are designed to rejuvenate depleted or suppressed T cells in the tumor microenvironment, relying on the immune system to control and kill tumors. However, accumulating evidence indicates that tumor-infiltrating neutrophils imped
Externí odkaz:
https://doaj.org/article/0664d93898e44ffbacb30c7ee045a1b1
Autor:
Zhihui Li, Keyan Yang, Yanzhi Song, Yongqiang Zhao, Fan Wu, Xiaopei Wen, Jing Li, Xianxuan Wang, Teng Xu, Xiaoyu Zheng, Qinglong Zheng, Tong Wu
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundPatients with refractory/relapsed (r/r) acute B lymphocytic leukemia (B-ALL) can achieve complete response (CR) after chimeric antigen receptor T-cell (CAR-T) therapy, but recurrence occurs in the short term. To reduce recurrence and improv
Externí odkaz:
https://doaj.org/article/6b9e8277f780404b8bdf0840eea095de
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundReduced intensity conditioning (RIC) before allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been reported to have the same overall survival (OS) as myeloablative conditioning (MAC) for patients with acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/11f1ffd6b3334ce481519c9bd26b900e
Autor:
Chaoyang Lai, Cong Li, Mengyang Liu, Qiujun Qiu, Xiang Luo, Xinrong Liu, Ling Hu, Yihui Deng, Yanzhi Song
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 4, Pp 455-464 (2019)
Accelerated blood clearance (ABC) phenomenon is common in many PEGylated nanocarriers, whose mechanism has not been completely elucidated yet. In this study, the correlation between Kupffer cells (KCs) and ABC phenomenon has been studied by KCs-targe
Externí odkaz:
https://doaj.org/article/4ab3b855192140d19750ec167acfdee4