Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Yanzhi Qian"'
1
Akademický článek
The role of liver cancer stem cells in hepatocellular carcinoma metastasis
Autor: Qinghui Niu, Susu Ye, Liu Zhao, Yanzhi Qian, Fengchao Liu
Publikováno v: Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
ABSTRACTMetastasis accounts for the vast majority of cancer deaths; however, this complex process has yet to be fully explained. To form metastases, cancer cells must undergo a series of steps, known as the “Metastatic cascade”, each of which req
Externí odkaz: https://doaj.org/article/9e5d987a3c1749ddb0509cc861c7c5f4
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2
Akademický článek
Prolonged inhibition of class I PI3K promotes liver cancer stem cell expansion by augmenting SGK3/GSK-3β/β-catenin signalling
Autor: Fengchao Liu, Xiaoling Wu, Xin Jiang, Yanzhi Qian, Jian Gao
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Abstract Background Serum and glucocorticoid-regulated kinase 3 (SGK3) has been reported to play an important role in tumour progression, but its role in cancer stem cells (CSCs) remains obscure. The phosphoinositide 3-kinase (PI3K) pathway is consid
Externí odkaz: https://doaj.org/article/2716e170ad1c419c96c691c94bdf9262
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5
The role of CD133 in hepatocellular carcinoma
Autor: Fengchao Liu, Yanzhi Qian
Publikováno v: Cancer Biol Ther
Cancer stem cells (CSCs) represent a small subpopulation of cells found within tumors that exhibit properties of self-renewal, like normal stem cells. CSCs have been defined as a crucial factor involved in driving cancer relapse, chemoresistance and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be0c117cb70b54bfcfded7b378865fe
https://doi.org/10.1080/15384047.2021.1916381
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6
PIK3C3 regulates the expansion of liver CSCs and PIK3C3 inhibition counteracts liver cancer stem cell activity induced by PI3K inhibitor
Autor: Yanzhi Qian, Fengchao Liu, Yiying Wang, Xiaoling Wu, Xin Jiang, Jian Gao
Publikováno v: Cell Death and Disease, Vol 11, Iss 6, Pp 1-13 (2020)
Cell Death & Disease
The existence of cancer stem cells (CSCs) accounts for hepatocellular carcinoma (HCC) treatment resistance, relapse, and metastasis. Although the elimination of cancer stem cells is crucial for cancer treatment, strategies for their elimination are l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27303e3c5ba379356ca34b404323b251
http://link.springer.com/article/10.1038/s41419-020-2631-9
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7
Aquaporin-9, Mediated by IGF2, Suppresses Liver Cancer Stem Cell Properties via Augmenting ROS/β-Catenin/FOXO3a Signaling
Autor: Zhe-chuan Mei, Xi Zheng, Keqi Yu, Hongyu Chen, Shasha Shi, Yanzhi Qian, Chuanfei Li
Publikováno v: Molecular cancer research : MCR. 18(7)
Liver cancer stem cells (LCSCs) play a critical role in hepatocellular carcinoma (HCC) by virtue of their aggressive behavior and association with poor prognoses. Aquaporin-9 (AQP9) is a transmembrane protein that transports water and reportedly tran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487009163e1293b3260f3e98c821bf8f
https://pubmed.ncbi.nlm.nih.gov/32229502
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8
AQP9 suppresses hepatocellular carcinoma cell invasion through inhibition of hypoxia-inducible factor 1α expression under hypoxia
Autor: Shengtao Liao, Xi Zheng, Zhe-chuan Mei, Lin Lv, Fengchao Liu, Yanzhi Qian, Wenguang Zhang
Publikováno v: Journal of gastroenterology and hepatologyReferences. 35(11)
Background and aim Intratumor hypoxia is a hallmark of hepatocellular carcinoma (HCC) and is associated with an aggressive tumor phenotype. Although it has been shown that AQP9 plays an important role in HCC, the relevance between hypoxia and AQP9 is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618e13338c0507437df893482b3ae943
https://pubmed.ncbi.nlm.nih.gov/32115773
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10
Prolonged inhibition of class I PI3K promotes liver cancer stem cell expansion by augmenting SGK3/GSK-3β/β-catenin signalling
Autor: Xiaoling Wu, Fengchao Liu, Xin Jiang, Jian Gao, Yanzhi Qian
Publikováno v: Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)
Background Serum and glucocorticoid-regulated kinase 3 (SGK3) has been reported to play an important role in tumour progression, but its role in cancer stem cells (CSCs) remains obscure. The phosphoinositide 3-kinase (PI3K) pathway is considered a ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b896d423b2c85e6fce248a4ffe2ed38d
https://pubmed.ncbi.nlm.nih.gov/29940988
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