Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yanzhi, Yuan"'
Autor:
Limin Shang, Yuehui Zhang, Yuchen Liu, Chaozhi Jin, Yanzhi Yuan, Chunyan Tian, Ming Ni, Xiaochen Bo, Li Zhang, Dong Li, Fuchu He, Jian Wang
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 4, Pp 795-807 (2022)
Genome-wide physical protein–protein interaction (PPI) mapping remains a major challenge for current technologies. Here, we reported a high-efficiency BiFC-seq method, yeast-enhanced green fluorescent protein-based bimolecular fluorescence compleme
Externí odkaz:
https://doaj.org/article/e432f4cc46104e6b92fbee44a981d6dc
Autor:
Xiuyuan Zhang, Qijian Zheng, Xiuying Yue, Zhanna Yuan, Jiming Ling, Yanzhi Yuan, Yanying Liang, Aihua Sun, Yuchen Liu, Hui Li, Kaikun Xu, Fuchu He, Jian Wang, Jin Wu, Chunling Zhao, Chunyan Tian
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Dysfunctional p53 signaling is one of the major causes of hepatocellular carcinoma (HCC) tumorigenesis and development, but the mechanisms underlying p53 inactivation in HCC have not been fully clarified. The role of Krüppel-asso
Externí odkaz:
https://doaj.org/article/fa52a4bc588449718587dfde6445ffd8
Autor:
Juncheng Wei, Yanzhi Yuan, Lu Chen, Yuanming Xu, Yuehui Zhang, Yajun Wang, Yanjie Yang, Clara Bien Peek, Lauren Diebold, Yi Yang, Beixue Gao, Chaozhi Jin, Johanna Melo-Cardenas, Navdeep S. Chandel, Donna D. Zhang, Hui Pan, Kezhong Zhang, Jian Wang, Fuchu He, Deyu Fang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
HRD1 is an E3 ligase known to play a role in targeting degradation of misfolded proteins in the ER. Here the authors show that HRD1 interacts with metabolic enzymes and its liver specific deficiency results in lower body weight, blood glucose and pla
Externí odkaz:
https://doaj.org/article/dbba9017edc14c20b4a2be08a43dd76f
Publikováno v:
Forests; Volume 14; Issue 7; Pages: 1282
Bursaphelenchus xylophilus, also known as the pine wood nematode (PWD), which causes pine wilt disease (PWD), is one of the most devastating diseases affecting pine forests globally. G protein-coupled receptors (GPCRs) are crucial in many biological
Autor:
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-10 (2011)
Abstract Proteome‐scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. Howev
Externí odkaz:
https://doaj.org/article/0ead80b5675642dfaa3229842189f163
Autor:
Yanying, Liang, Xiuyuan, Zhang, Wenwen, Geng, Yun, Wang, Yue, Ding, Qin, Song, Yanzhi, Yuan, Chunling, Zhao, Zhaoju, Tian, Jian, Wang, Chunyan, Tian
Publikováno v:
Cellular Signalling. 98:110405
As one of the most important tumor suppressors, the activity of p53 is precisely regulated. However, the mechanism of p53 regulation is still being elucidated and new regulatory molecules for p53 have also been frequently identified. Our previous wor
Autor:
Li Zhang, Fuchu He, Jian Wang, Yanzhi Yuan, Ming Ni, Dong Li, Chunyan Tian, Chaozhi Jin, Yuehui Zhang, Yuchen Liu, Limin Shang, Xiaochen Bo
Genome-wide physical protein-protein interaction (PPI) mapping remains a major challenge for current technologies. Here, we reported a high-efficiency BiFC-seq method, yeast-enhanced green fluorescent protein-based bimolecular fluorescence complement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e259984b36c0e7c593248d393cd7171a
https://doi.org/10.1101/2020.06.16.154146
https://doi.org/10.1101/2020.06.16.154146
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49567 (2012)
STAT3 is a key transcription factor that mediates various cellular and organismal processes, such as cell growth, apoptosis, immune response and cancer. However, the molecular mechanisms of STAT3 regulation remain poorly understood. Here, we identifi
Externí odkaz:
https://doaj.org/article/a33299f283bd4500a0b40ec25864cc2c
Autor:
Fuchu He, Chaozhi Jin, Lauren Diebold, Yuehui Zhang, Kezhong Zhang, Juncheng Wei, Yanzhi Yuan, Yajun Wang, Yanjie Yang, Lu Chen, Clara Bien Peek, Donna D. Zhang, Beixue Gao, Navdeep S. Chandel, Yi Yang, Yuanming Xu, Jian Wang, Johanna Melo-Cardenas, Hui Pan, Deyu Fang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
The HMG-CoA reductase degradation protein 1 (HRD1) has been identified as a key enzyme for endoplasmic reticulum-associated degradation of misfolded proteins, but its organ-specific physiological functions remain largely undefined. Here we show that
Autor:
Chaozhi Jin, Yanzhi Yuan, Jian Wang, Fuchu He, Cheng Chang, Fangbing Liu, Yunping Zhu, Xiuyuan Zhang, Chunyan Tian, Yuehui Zhang
Publikováno v:
Journal of Proteome Research. 16:170-178
Exosomes are secreted small vesicles that mediate various biological processes, such as tumorigenesis and immune response. However, whether the inflammasome signaling leads to the change of constituent of exosomes and its roles in immune response rem